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Children with chronic medical conditions often need multiple intravenous (IV) access instances during their hospitalizations, both peripheral and central. Obtaining a working IV in this patient population undergoing general anesthesia can be challenging.
Phat T. Dang, Binjon Sriratana
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Mouse monocytes express CD127 by immune cells, not LPS
The essential role of interleukin 7 (IL-7) signaling via its receptor (IL-7Rα; CD127) in T cell development and function has been well documented. However, CD127 expression and function in myeloid cells, including monocytes, are less clear, especially in
Reza Yazdani +7 more
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IL-27 regulates IL-18 binding protein in skin resident cells [PDF]
IL-18 is an important mediator involved in chronic inflammatory conditions such as cutaneous lupus erythematosus, psoriasis and chronic eczema. An imbalance between IL-18 and its endogenous antagonist IL-18 binding protein (BP) may account for increased ...
Wittmann, M +23 more
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The growth of T cells ex vivo for the purpose of T cell therapies is a rate-limiting step in the overall process for cancer patients to achieve remission. Growing T cells is a fiscally-, time-, and resource-intensive process. Cytokines have been shown to
Brooks Hopkins +6 more
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Soluble CD127 potentiates IL‐7 activity in vivo in healthy mice
Introduction Soluble forms of cytokine receptors can be involved in the endogenous regulation of cytokine activity. Soluble interleukin 7 receptor α (sCD127) naturally binds IL‐7, therefore there is interest in its potential application as an ...
Nawaf A. Aloufi +7 more
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Long-lived memory cell formation and maintenance are usually regulated by cytokines and transcriptional factors. Adjuvant effects of IL-7 have been studied in the vaccines of influenza and other pathogens.
Jiangyuan Han +10 more
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Pro-inflammatory signaling by IL-10 and IL-22: bad habit stirred up by interferons? [PDF]
Interleukin (IL)-10 and IL-22 are key members of the IL-10 cytokine family that share characteristic properties such as defined structural features, usage of IL-10R2 as one receptor chain, and activation of signal transducer and activator of ...
Heiko Mühl, Heiko eMühl, Mühl, Heiko
core +1 more source
IMMUNE PARAMETERS IN PATIENTS WITH BREAST CANCER AFTER RADIOTHERAPY AND SURGICAL TREATMENT
. Some immune parameters (cell subsets in peripheral blood, spontaneous and LPS-induce production of IL-1β, IL-5, IL-7, IL-12, IL-13, IL-17, G-CSF, MCP-1 and MIP-1β in whole blood cultures) were studied in fifty patients with breast cancer (T2-3, N0-3 ...
Yu. B. Selikhova +8 more
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(A) Gene expression profiling identified Mmp7 as one of the top up-regulated gene in Asc-/- and Nlrp3-/- mice with bladder pathology (CFT073 infected mice, 7 days). Log2 fold change of Mmp7 expression levels in individual mice are shown relative to the H&
Björn Wullt (243099) +10 more
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Characterization of lymph node stromal cells during Treg-mediated tolerance [PDF]
Solid organs transplantation is therapy of choice for several human diseases. The success of this treatment is determined by the recipientÕs ability to prevent rejection.
Broggi, Maria Anna Sofia
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