Results 11 to 20 of about 80,108,489 (239)

IL-7 Induces an Epitope Masking of γc Protein in IL-7 Receptor Signaling Complex [PDF]

open access: yesMediators of Inflammation, 2017
IL-7 signaling via IL-7Rα and common γ-chain (γc) is necessary for the development and homeostasis of T cells. Although the delicate mechanism in which IL-7Rα downregulation allows the homeostasis of T cell with limited IL-7 has been well known, the ...
Tae Sik Goh   +11 more
doaj   +2 more sources

IL-7-dependent maintenance of ILC3s is required for normal entry of lymphocytes into lymph nodes

open access: yes, 2021
IL-7 is essential for the development and homeostasis of T and B lymphocytes and is critical for neonatal lymph node organogenesis because Il7-/- mice lack normal lymph nodes.
Natalie Papazian (11282574)   +7 more
core   +1 more source

Flip the coin: IL-7 and IL-7R in health and disease [PDF]

open access: yes, 2019
The cytokine IL-7 and its receptor, IL-7R, are critical for T cell and, in the mouse, B cell development, as well as differentiation and survival of naive T cells, and generation and maintenance of memory T cells.
Benedict Seddon   +8 more
core   +1 more source

Interleukin 7 from maternal milk crosses the intestinal barrier and modulates T-cell development in offspring [PDF]

open access: yes, 2011
Background Breastfeeding protects against illnesses and death in hazardous environments, an effect partly mediated by improved immune function. One hypothesis suggests that factors within milk supplement the inadequate immune response of the offspring,
Andrew M Prentice   +11 more
core   +2 more sources

Characterization of lymphoid tissue inducer cells and lymphoid tissue development in adult interleukin 7 transgenic mice [PDF]

open access: yes, 2008
During embryogenesis, the development of secondary lymphoid organs (SLOs) such as lymph nodes (LNs) and Peyer’s patches (PPs) requires the cellular crosstalk between vascular cell adhesion molecule (VCAM)-1+ mesenchymal organizer cells and CD45+CD4 ...
Schmutz, Sandrine
core   +1 more source

Network-Based Assessment of Minimal Change Disease Identifies Glomerular Response to IL-7 and IL-12 Pathways Activation as Innovative Treatment Target

open access: yesBiomedicines, 2023
Background: Minimal change disease (MCD), a major cause of nephrotic syndrome, is usually treated by corticosteroid administration. MCD unresponsiveness to therapy and recurrences are nonetheless frequently observed, particularly in adults.
Øystein Eikrem   +12 more
doaj   +1 more source

Comparative analysis of the lambda-interferons IL-28A and IL-29 regarding their transcriptome and their antiviral properties against hepatitis C virus. [PDF]

open access: yes, 2010
Specific differences in signaling and antiviral properties between the different Lambda-interferons, a novel group of interferons composed of IL-28A, IL-28B and IL-29, are currently unknown.
Ralf Bartenschlager   +28 more
core   +1 more source

Il PCI, Autonomia Operaia e l'emergenza terrorismo: il caso 7 aprile 1979

open access: yesStoricamente, 2017
The article analyzes the positions of the Italian Communist Party towards the large political movement that took action on its left, especially “Autonomia Operaia”, in the late seventies, during the terrorism emergency and the crisis of ...
Giulia Pacifici
doaj   +1 more source

Immunomodulation with IL-7 and IL-15 in HIV-1 infection

open access: yesJournal of Virus Eradication, 2023
Immunomodulating agents are substances that modify the host immune responses in diseases such as infections, autoimmune conditions and cancers. Immunomodulators can be divided into two main groups: 1) immunostimulators that activate the immune system ...
Jesper D. Gunst   +3 more
doaj   +1 more source

Management Behaviors of Illness at Type 2 Diabetes Patients

open access: yesAhi Evran Medical Journal, 2023
Purpose: The aim of the study is to reveal the knowledge level about the diseases of type 2 diabetics and their knowledge and application of tertiary prevention practices and related factors.
Seçkin ÖZSAYDI , Arda BORLU, Hasan BAL
doaj   +1 more source

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