Computer modeling of the peculiarities in the interaction of IL-1 with its receptors in schizophrenia [PDF]
One of the primary theories regarding the development of schizophrenia revolves around genetics, indicating the involvement of hereditary factors in various processes, including inflammation.
N. Yu. Chasovskikh +2 more
doaj +2 more sources
Association between vitamin D receptor gene polymorphisms, inflammatory cytokines (IL-1, IL-6, and IL-10), and fracture healing in sports-related injuries [PDF]
Background: In this study, we analysed the correlation between polymorphisms in the Vitamin D receptors (VDR) gene at the Apa I and FoK I loci and sports-related fractures (SRF).
Wang Dan
doaj +2 more sources
Low-level Laser Therapy and Changes in Salivary Proinflammatory Cytokines: A Systematic Review [PDF]
Background: The effect of laser on reducing inflammation has always been considered. The aim of this study was to evaluate the clinical studies on the effect of using low-power lasers on the production and activity of proinflammatory cytokines such as IL-
Fatemeh Baljani +4 more
doaj +1 more source
Anemia of inflammation in patients with colorectal cancer: Correlation with interleukin-1, interleukin-33 and galectin-1 [PDF]
Background: Patients with colorectal cancer (CRC) have anemia often present as a consequence of chronic bleeding from tumor. The exact role of lL-33, Galectin-l and IL-l in the pathological genesis of anemia in colorectal cancer patients has not been ...
Jocić Miodrag +8 more
doaj +1 more source
The complexity of diagnosing and predicting the course of TNF-receptor-associated periodic syndrome TRAPS determines the importance of studying the dependence of clinical manifestations on the variant of genetic mutation and the presence of modifier ...
E. V. Antsiferova +9 more
doaj +1 more source
Improving cancer immunotherapy by targeting IL-1
Interleukin-1 (IL-1) is an inflammatory cytokine associated with tumor invasiveness and metastasis. We recently found that baseline IL-1 in melanomas promoted resistance to immunotherapy by creating an immunosuppressive tumor microenvironment and that IL-
Zhilan Xiao +2 more
doaj +1 more source
Prediction of diacerein inhibition activity against interleukin-1 receptors through docking method and tracing of pharmacokinetic profiles and their toxicity [PDF]
IL-1 is one of the cytokines involved in joint diseases such as osteoarthritis. IL-1 plays a role in maintaining the balance of proteolytic proteins:MMPs and TIMPs inhibitors.
Frengki Frengki +5 more
doaj +1 more source
IL-1 and autoinflammatory disease: biology, pathogenesis and therapeutic targeting
Over 20 years ago, it was first proposed that autoinflammation underpins a handful of rare monogenic disorders characterized by recurrent fever and systemic inflammation.
L. Broderick, H. Hoffman
semanticscholar +1 more source
Background: Immunotherapy for wart employs ability of immune system to recognize certain viral, bacterial, and fungal antigens in previously sensitized individual inducing Type IV delayed-type hypersensitivity reaction (up-regulated Th1 cytokines IL-1 ...
Amrita Sil +5 more
doaj +1 more source
Alternative Pathways of IL-1 Activation, and Its Role in Health and Disease
Cytokines activate or inhibit immune cell behavior and are thus integral to all immune responses. IL-1α and IL-1β are powerful apical cytokines that instigate multiple downstream processes to affect both innate and adaptive immunity.
Katerina Pyrillou +2 more
semanticscholar +1 more source

