Results 121 to 130 of about 1,896,687 (246)

D113. Comparison of Methodologies for Craniofacial Soft-tissue Cephalometrics: The Value of Virtual Reality

Plastic and Reconstructive Surgery, Global Open, 2023
John Vandevender, BS, Akriti Choudhary, MBBS, Sobhi Kazmouz, BA, Marina A. Lentskevich, BS, Michael Edgar, DC, Christopher Juarez, BS, Julius Mendoza, Kevin Yang, MD, Kyle Bartelt, MD, Alvin Nguyen, BA, Chad A. Purnell, MD   +10 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

IL-1 delineates squalene-based adjuvant efficacy and reactogenicity in a cell-type-specific manner. [PDF]

NPJ Vaccines
Yoshioka Y, Nishinaka-Yoshioka A, Kobiyama K, Hayashi T, Kidani Y, Yanagida Y, Kasahara J, Tsujii K, Asaoka Y, Kuroda N, Kugimiya A, Osawa H, Yoshimura A, Onishi M, Nakagawa T, Ishida S, Omoto S, Nagira M, Coban C, Ishii KJ.   +19 more
europepmc   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Pro-Inflammatory Synergy Between IL-17, IL-1 and Hyperuricemia in Psoriatic Arthritis: Clinical Implications of a Pilot Study. [PDF]

Diseases
Suiu LI, Vreju FA, Turcu-Stiolica A, Bita CE, Boldeanu MV, Ciurea PL.   +5 more
europepmc   +1 more source

QS75. Bone Bending: Developing an Animal Model For Mechanical Properties of Human Infant Calvarium

Plastic and Reconstructive Surgery, Global Open, 2022
Devansh Saini, PhDc, Lee Alkureishi, MD, Russell Reid, MD, PhD, Pravin Patel, MD, Linping Zhao, PhD, Roberto Leonardo Diaz, PhD, Farid Amirouche, PhD   +6 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

The effect of IL-1 blockers on exertional leg pain in familial Mediterranean fever patients: an exploratory study. [PDF]

Rheumatology (Oxford)
Druyan A, Livneh A, Giat E, Ben-Zvi I, Lidar M.   +4 more
europepmc   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

IL-1 signaling and inflammasomes in acute myeloid leukemia: mechanisms and therapeutic opportunities. [PDF]

Cell Mol Life Sci
Mortellaro A, Mastaglio S, Muzio M.
europepmc   +1 more source