Results 131 to 140 of about 1,896,687 (246)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Age- and Genotype-Associated Specific Expression of IL-1 and TNF Receptors on Immunocompetent Cells. [PDF]

Int J Mol Sci
Zhukova J, Lopatnikova J, Vasilyev F, Alshevskaya A, Lipa D, Sennikov S.   +5 more
europepmc   +1 more source

ACTH Regulation and IL-1 [PDF]

Science, 1988
openaire   +2 more sources

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

TAFRO syndrome requiring combined IL 6 and IL 1 inhibition: a case report. [PDF]

Front Immunol
Sultan AW, Grießhammer E, Hinrichs C, Trenkmann L, Oschlies I, Hanitsch LG, Haibel H, Schneider T, Leistner R.   +8 more
europepmc   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

IL-1 Receptor Antagonist Antibodies in Idiopathic Recurrent Pericarditis. [PDF]

JAMA Netw Open
Wu MA, Kessel C, Fadle N, Regitz E, Fuehner S, Negro E, Berra S, Pfeifer J, Ceriani E, Thurner B, Klingel K, Caforio A, Imazio M, Brucato A, Thurner L.   +14 more
europepmc   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Early IL-1 Inhibition in Still's Disease: A Window of Opportunity for Improving Outcomes. [PDF]

ACR Open Rheumatol
Bindoli S, Cadore C, Guidea I, Doria A, Ramonda R, Sfriso P.   +5 more
europepmc   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source