Results 261 to 270 of about 34,732,115 (289)
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Targeting IL-1 in depression

Expert Opinion on Therapeutic Targets, 2012
Depression is associated with inflammation, Th1 and Th17 responses, oxidative and nitrosative stress (O&NS), autoimmune responses against neoantigenic determinants, and neuroprogression (i.e., neurodegeneration, impaired plasticity and reduced neurogenesis).
Michael, Maes, Cai, Song, Raz, Yirmiya
openaire   +2 more sources

IL-1 induces rapid phosphorylation of the IL-1 receptor.

The Journal of Immunology, 1989
Abstract The IL-1R on murine T cells is a Mr = 80,000 plasma membrane glycoprotein. cDNA cloning and transfection experiments have shown that this is an integral membrane protein, which binds both IL-1 alpha and IL-1 beta and transduces the IL-1 signal.
B, Gallis   +6 more
openaire   +2 more sources

Species-specific binding of IL-1, but not the IL-1 receptor antagonist, by fibroblasts

Cytokine, 1994
Our laboratory previously reported that bovine thymocytes and fibroblasts proliferated only in response to bovine IL-1, whereas proliferation of murine thymocytes was augmented equally well by murine, human, and bovine IL-1. In this study, we used direct and competitive receptor binding assays to determine whether differential binding of homologous ...
J A, Lederer, C J, Czuprynski
openaire   +2 more sources

Out of many, IL-1

Immunity
Sick animals often show reduced social engagement, a form of adaptive behavioral distancing thought to limit pathogen transmission beyond the infected individual. In a recent issue of Cell, Yang et al. identified a defined molecular and anatomical pathway through which inflammatory signals are sensed by the brain and translated into active social ...
Jinsu Lee, Michael A. Wheeler
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IL-1 Receptor Family

2017
IL-1 receptor ...
openaire   +3 more sources

??????????????-???????????????????????????? ???????????? ???????????????????????????????????? ???????????????? IL-1?? ?????????????????????????????? ?????????????????????? ?????? ?????????????????????? ?????????????????? ?? ?????????????????????? ???????????????? ?????????????????????????????? ?? ?????????????? ?? ???????????????????? ???????????? ??????????????????????????

2013
?? ???????????? ???? ?????? ?? ?????? ?????????????? ???????????? ?????????????????? ?? ???????????????????????????? ???????????????????? ???????????????? ???????????????????????????? ???????????????????? ???? ??????????????????????, ???? ???????????????? ???????? ?????????????????????????? ???????????????????????????????? ???????????????????? ?????????
openaire   +1 more source

???????????????? ???????????? ???????????????????????????????????? ???????????????? IL-1?? ?? ???????????????????????????? ?????????????? ?????? ???????????????? ?????????????????? ???????? ?????????????? ???????????????????? ???????? ?? ??????, ???????????????????? ???????????????????? ????????????

2014
?? ???????????? ???? ?????????????????? ?????????????????????????? ?????????????????????????? ???????????? (????????), ?????? ?????????????????? ?????????????????????? (??????) ????????????, ?????????????? ?????????? ???????????? ???????? ?????????????????? ???? ?????????????????????? (?? ???????????????????????? ????????????????????) ???????????? ?????
openaire   +1 more source

?????????????? ???????????????????? ??????????-?????????????????????? ???? ???????????????? IL-1?? ?? ?????????????? ?????????????????? ?? ??????????????????

2015
We have investigated the effect of systemic therapy of obesity on regulation of cytokine IL-1?? synthesis in psoriasis patients produced by healthy donors??? keratinocytes through mononuclear leukocytes (leptin-induced) in vitro. It has been shown that the treatment course with use of acarbose results in a statistically significant reduction or ...
openaire   +1 more source

IL-1

2021
openaire   +1 more source

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