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Zeitschrift für Rheumatologie, 2010
Interleukin (IL)-1 plays an important role not only in the mediation of inflammation but also in the destruction of cartilage and bone. Together with TNF-alpha it is one of the most important cytokines in the pathogenesis of rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA).
I. Kötter, G. Horneff
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Interleukin (IL)-1 plays an important role not only in the mediation of inflammation but also in the destruction of cartilage and bone. Together with TNF-alpha it is one of the most important cytokines in the pathogenesis of rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA).
I. Kötter, G. Horneff
openaire +1 more source
Induction of IL-1: independent production of IL-1 alpha and IL-1 beta.
Cytokine, 1992Lipopolysaccharide (LPS) either in its soluble form or associated with multilamellar phospholipid vesicles (liposomes) was investigated for its ability to induce human monocyte interleukin (IL)-1 alpha and IL-1 beta. When human monocytes were activated in vitro by LPS either in its soluble form or presented at the surface of lyophilized multilamellar ...
O, Bakouche, J L, Moreau, L B, Lachman
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2017
The family of IL-1 cytokines (IL-1F) encompasses eleven proteins that share similar structure and signaling mode (similar receptors, similar signaling pathways) (Dinarello 2013). IL-1F cytokines are involved in initiation as well as regulation of inflammation and are central players of innate immunity.
Boraschi, D.
openaire +2 more sources
The family of IL-1 cytokines (IL-1F) encompasses eleven proteins that share similar structure and signaling mode (similar receptors, similar signaling pathways) (Dinarello 2013). IL-1F cytokines are involved in initiation as well as regulation of inflammation and are central players of innate immunity.
Boraschi, D.
openaire +2 more sources
Zeitschrift fur Rheumatologie, 2011
Interleukin (IL)-1 plays an important role not only in the mediation of inflammation but also in the destruction of cartilage and bone. Together with TNF-alpha it is one of the most important cytokines in the pathogenesis of rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA).
I, Kötter, G, Horneff
openaire +1 more source
Interleukin (IL)-1 plays an important role not only in the mediation of inflammation but also in the destruction of cartilage and bone. Together with TNF-alpha it is one of the most important cytokines in the pathogenesis of rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA).
I, Kötter, G, Horneff
openaire +1 more source
2013
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openaire +1 more source
2014
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2015
We have investigated the effect of systemic therapy of obesity on regulation of cytokine IL-1?? synthesis in psoriasis patients produced by healthy donors??? keratinocytes through mononuclear leukocytes (leptin-induced) in vitro. It has been shown that the treatment course with use of acarbose results in a statistically significant reduction or ...
openaire +1 more source
We have investigated the effect of systemic therapy of obesity on regulation of cytokine IL-1?? synthesis in psoriasis patients produced by healthy donors??? keratinocytes through mononuclear leukocytes (leptin-induced) in vitro. It has been shown that the treatment course with use of acarbose results in a statistically significant reduction or ...
openaire +1 more source