Results 21 to 30 of about 1,850,686 (245)

Type I IL-1 Receptor Mediates IL-1 and Intracellular IL-1 Receptor Antagonist Effects in Skin Inflammation [PDF]

Journal of Investigative Dermatology, 2007
The IL-1 system plays a key role in skin physiology and pathology. In this study, we used mutant mice lacking the type I IL-1 receptor (IL-1RI), lacking IL-1 receptor antagonist (IL-1Ra), or overexpressing the human intracellular (ic) IL-1Ra1 isoform, as well as combinations thereof, to dissect the role of the IL-1 system in phorbol 13-myristate 12 ...
Palmer, Gaby, Talabot-Ayer, Dominique, Kaya, Gürkan, Gabay, Cem   +3 more
openaire   +2 more sources

Effects of short- and long-term regular exercise on reproductive tissue in streptozotocin-induced diabetic male Wistar rats

Endocrine Regulations, 2018
Objective. Reproductive disorders are one of the complications of diabetes mellitus. Since conflicting results have been obtained from different studies, which examined serum levels of cytokines in patients with diabetes, and considering the fact that ...
Mogaddami Zahra, Sheikhzadeh Farzam, Hatami Homeira, Khojasteh Seyed Mahdi Banan, Khajehnasiri Nazli, Hemmati Ali Reza Ali, Dastranj Ali   +6 more
doaj   +1 more source

Application of anakinra in inflammatory dermatoses

Pifu-xingbing zhenliaoxue zazhi
Interleukin 1(IL-1) is an important cytokine, which is involved in the development of many inflammatory diseases. IL-1 inhibitors have become an effective approach in the treatment of these diseases.
Xiaomei YOU, Ganlin GU, Yanyun JIANG, Liangchun WANG   +3 more
doaj   +1 more source

IL-1 and Allergy

Allergology International, 2010
IL-1 is a well-characterized proinflammatory cytokine that is involved in host defense and autoimmune diseases. IL-1 can promote activation of T cells, including Th1 cells, Th2 cells and Th17 cells, and B cells, suggesting that IL-1 may contribute to the development of various types of T-cell-mediated diseases.
Aya, Nambu, Susumu, Nakae
openaire   +2 more sources

The Effect of D-Peptide-B and B.Bifidum Probiotic Lysate on the Expression of TNF-α and IL-1 Genes in AGS Cancer Cell Line Compared to Healthy HEK Cells [PDF]

پیاورد سلامت, 2023
Background and Aim: Today, natural compounds such as peptides and probiotics can be mentioned as a supplement to the treatment of diseases such as cancer.
Shima Derakhshan, Negar Yavari Tehrani Fard, Nahid Abotalbe, Maryam Naseroleslami   +3 more
doaj  

Communication and Language Profiles of Children Treated for Posterior Fossa Brain Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cognitive and language deficits are frequently reported sequelae of posterior fossa brain tumors (PFBT). Typically, delayed onset impedes prompt assessment and early intervention. This has devastating implications for quality of life.
Zara Sved, Meghan Hesse, Jennie Cusiter, Annabel Webb, Kimberley Docking   +4 more
wiley   +1 more source

SPECIFIC STAGE-DEPENDENT FEATURES OF CYTOKINE CASCADE IN THE PATIENTS WITH BRONCHIAL ASTHMA

Медицинская иммунология, 2014
. A study of leukocyte regulation system in patients with exacerbated bronchial asthma (BA) was performed by means of measuring spontaneous and induced production of certain cytokines (IL-4, IL-1b, IL-10 and IFNg) in whole blood, and drawing some ...
L. V. Ryabova, A. V. Zurochka
doaj   +1 more source

The HIT Network for Children and Adolescents With CNS Tumors Facilitates Improvements of Diagnostic Assessments, Multimodal Treatments, Individual Counseling, and Research in Germany, Austria, and Switzerland

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The HIT network was established in 2000 to create a population‐based structure aiming to improve survival rates and reduce late effects for children with central nervous system (CNS) tumors by conducting comprehensive clinical trials.
Stefan Rutkowski, Michael C. Frühwald, Gudrun Fleischhack, Stephan Tippelt, Pablo Hernáiz‐Driever, Olaf Witt, Astrid Gnekow, Christof Kramm, Matthias Eyrich, Johannes E. A. Wolf, Hermann Müller, Carsten Friedrich, Uwe R. Kordes, Denise Obrecht‐Sturm, Petra Ketteler, Barbara von Zezschwitz, Pascal Johann, Dominik Sturm, Karoline Nemes, Stefan Schönberger, Till Milde, Brigitte Bison, Monika Warmuth‐Metz, Torsten Pietsch, Ulrich Schüller, Arend Koch, David Capper, Martin Hasselblatt, Christian Thomas, Christian Hagel, Stefan M. Pfister, Felix Sahm, David T. W. Jones, Martin U. Schuhmann, Jürgen Krauss, Pedram Emami, Ahmed El Damaty, Rolf D. Kortmann, Rudolf Schwarz, Jürgen Debus, Mechthild Krause, Fabian Pohl, Holger Ottensmeier, Lisa Bußenius, Katja Baust, Andreas Faldum, Cecile Ronckers, Desiree Grabow, Martin Benesch, Thomas Perwein, Karin Dieckmann, Irene Slavc, Johannes Gojo, Nicolas U. Gerber, André O. von Bueren, Katrin Scheinemann, Gabriele Calaminus, Beate Timmermann, Ulrich‐Wilhelm Thomale, Martin Mynarek   +59 more
wiley   +1 more source

Stressful Events Reported by Childhood Cancer Survivors and Community Controls From the St. Jude Lifetime (SJLIFE) Cohort: A Mixed Method Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Characterizing stressful events reported by childhood cancer survivors experienced throughout the lifespan may help improve trauma‐informed care relevant to the survivor experience. Methods Participants included 2552 survivors (54% female; 34 years of age) and 469 community controls (62% female; 33 years of age) from the St.
Megan E. Ware, Colter K. Clayton, Fang Wang, Sedigheh Mirzaei, Kyla Shelton, Tara M. Brinkman, Victoria Willard, Katianne M. Howard Sharp, Kevin Krull, Lindsay F. Schwartz, Melissa M. Hudson, Gregory T. Armstrong, Kirsten K. Ness, Rachel T. Webster   +13 more
wiley   +1 more source

Optimization of Zebrafish Larvae Sectioning for Mass Spectrometry Imaging

Pharmaceuticals, 2022
The utility of zebrafish is becoming more frequent due to lower costs and high similarities to humans. Zebrafish larvae are attractive subjects for drug screening and drug metabolism research. However, obtaining good quality zebrafish larvae sections for
Junhai Yang, Lauren Rendino, Steven Cassar, Wayne Buck, James Sawicki, Nari Talaty, David Wagner   +6 more
doaj   +1 more source