Results 71 to 80 of about 28,037,829 (342)

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis, Shauna R. Campbell, Jonathan Jang, Eashwar Somasundaram, Chandana A. Reddy, Jacob G. Scott, Lilyana Angelov, Peter M. Anderson, Matteo Trucco, Zachary Burke, Lukas Nystrom, Nathan Mesko, Anthony Magnelli, Erin S. Murphy   +13 more
wiley   +1 more source

Different effects of continuous infusion of interleukin-1 and interleukin-6 on the hypothalamic-hypophysial-thyroid axis [PDF]

, 1994
The cytokines interleukin-1 (IL-1) and IL-6 are thought to be important mediators in the suppression of thyroid function during nonthyroidal illness.
Greef, W.J. de, Haasteren, G.A.C. (Goedele) van, Hermus, A.R.M.M. (Ad), Kaptein, E. (Ellen), Klootwijk, W. (Willem), Linkels, E., Meer, M.J. van der, Sweep, C.G., Toor, H. (Hans) van, Visser, T.J. (Theo)   +9 more
core   +1 more source

Highlighting the Effect of Pro-inflammatory Mediators in the Pathogenesis of Periodontal Diseases and Alzheimer’s Disease

Journal of Pharmacy and Bioallied Sciences
Alzheimer’s disease (AD) is a neurological condition that is much more common as people get older. It may start out early or late. Increased levels of pro-inflammatory cytokines and microglial activation, both of which contribute to the central nervous ...
Babiker Rasha, Mohammed Riham, Chaitanya Nallan CSK, Rahman Muhammed M, Gismalla Bakri   +4 more
doaj   +1 more source

The IL-1-Like Cytokine IL-33 Is Constitutively Expressed in the Nucleus of Endothelial Cells and Epithelial Cells In Vivo: A Novel ‘Alarmin’?

PLoS ONE, 2008
Background Interleukin-33 (IL-33) is an IL-1-like cytokine ligand for the IL-1 receptor-related protein ST2, that activates mast cells and Th2 lymphocytes, and induces production of Th2-associated cytokines in vivo.
C. Moussion, N. Ortéga, J. Girard
semanticscholar   +1 more source

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li, Raquel Revuelta Iniesta, Alan R. Barker, Dimitris Vlachopoulos, Tomáš Sláma, Christina Schindera, Fabiën N. Belle   +6 more
wiley   +1 more source

Response of human engineered cartilage based on articular or nasal chondrocytes to interleukin-1? and low oxygen [PDF]

, 2011
Previous studies showed that human nasal chondrocytes (HNC) exhibit higher proliferation and chondrogenic capacity as compared to human articular chondrocytes (HAC).
Andrea Barbero, Andrea Osmokrovic, Celeste Scotti, Francine Wolf, Giuseppe M. Peretti, Ivan Martin, Matricali G.A., Sylvie Miot, Wendt D.   +8 more
core   +1 more source

Evaluación de polimorfismos en los genes de TNF-alfa, TNF-beta e IL-1beta y sus variantes alélicas en una población colombiana de pacientes con sepsis

Iatreia, 2010
La sepsis se define como un síndrome de respuesta sistémica en presencia,  confirmada o sospechada de infección. Se manifiesta  con uno o varios marcadores de enfermedad general, inflamación, anormalidad hemodinámica, disfunción orgánica o falla de ...
Carolina Montoya Ruiz, Maira Alegandra Diosa Toro, Paula Andrea Velilla, Fabián Jaimes Barragán   +3 more
doaj  

Interleukin-1 involved in Apoptosis of Beta-Thalassemia/Hemoglobin E Erythroid Progenitor Cells

Asian Journal of Medical Sciences, 2013
Objective: The major pathophysiological features of β-thalassemia are anemia and ineffective erythropoiesis. Ineffective erythropoiesis has been shown by an intense marrow erythroid hyperplasia and increased apoptosis during basophilic to orthochromatic ...
Umesh Prasad Gupta
doaj   +1 more source

Cerebrospinal Fluid Liquid Biopsy Enables Targeted Therapy Without Tissue Diagnosis in Pediatric Low‐Grade Gliomas With BRAF V600E Mutation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We present two pediatric cases of pediatric low‐grade gliomas (PLGG) with BRAF V600E mutations diagnosed and monitored using cerebrospinal fluid (CSF) liquid biopsy analyzed via digital droplet PCR (ddPCR), without tissue biopsy. Both patients were treated with dabrafenib and trametinib and monitored through clinical assessments, magnetic ...
Hannah Sultan, Damien Faury, Alexander G. Weil, Harrison J. Westwick, Nada Jabado, Sébastien Perreault   +5 more
wiley   +1 more source

The effect and mechanism of IL-1 R II / IL-1 RAcp in Autoimmune Myocarditis [PDF]

, 2016
【目的】白介素-1（IL-1）是一种T淋巴细胞激活因子，大量研究报道，在心肌炎急性期表达量明显升高。白介素1受体II型（IL-1RII）可以招募白介素1受体辅助蛋白（IL-1RAcp），从而拮抗IL-1β的作用。本课题目的为评估IL-1RII和IL-1RAcp的重组质粒对大鼠自身免疫性心肌炎（EAM）的作用，并进一步探讨其机制，为心肌炎的临床治疗提供理论基础。 【方法】首先在临床实验中，我们选取厦门市心血管病医院诊断明确的心肌炎住院患者28例，应用bio ...
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