Results 101 to 110 of about 7,897,153 (261)
Scientific Reports, 2016 Cancer-associated fibroblasts (CAF) are recognized as one of the key determinants in the malignant progression of lung adenocarcinoma. And its contributions to chemoresistance acquisition of lung cancer has raised more and more attention.
Leilei Tao +7 more
semanticscholar +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objectives The association between exposure to dinutuximab beta (DB) and event‐free survival (EFS) or overall survival (OS) of neuroblastoma patients was assessed using data collected during three clinical trials (five cohorts). Methods A systematic review (March 2026) was conducted to identify relevant studies (prospective; registered DB ...
Przemysław Holko +19 more
wiley +1 more source
TMED3 promotes hepatocellular carcinoma progression via IL-11/STAT3 signaling
Scientific Reports, 2016 Transmembrane p24 trafficking protein 3(TMED3) is a metastatic suppressor in colon cancer, but its function in the progression of hepatocellular carcinoma (HCC) is unknown. Here, we report that TMED3 was up-regulated in HCC and portal vein tumor thrombus.
Hao Zheng +12 more
semanticscholar +1 more source
Targeting IL-11 signaling in colon cancer
Oncotarget, 2013 The development of Colorectal cancer (CRC), the fourth most common cause of malignancy worldwide, is driven by the sequential accumulation of genetic changes. In the Western world, more than 80% of sporadic CRC cases arise from aberrant activation of the WNT-pathway, including mutations in the adenomatous polyposis coli (APC) tumor suppressor gene and ...
Ernst, M, Putoczki, TL
openaire +3 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Results of COG ANBL1221 changed treatment paradigms for patients with relapsed/refractory neuroblastoma. Chemoimmunotherapy with irinotecan/temozolomide/dinutuximab is now used as both bridge therapy following suboptimal response to induction and as treatment in first relapse.
Elizabeth Sokol +6 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Medication nonadherence during the first 100 days after pediatric hematopoietic stem cell transplantation (HSCT) and during oncology treatment increases risk for complications. BMT4me is a caregiver‐facing mobile health (mHealth) application providing medication reminders, symptom tracking, and note‐taking features to support ...
Micah A. Skeens +4 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Survival after relapse in pediatric acute myeloid leukemia (AML) remains poor, highlighting the critical importance of identifying prognostic factors to guide optimal relapse management. Methods We investigated the prognostic impact of multiparameter flow cytometry (MFC) measurable residual disease (MRD) in 188 patients with first ...
Camilla Poulsen +21 more
wiley +1 more source
BMC Cancer, 2013 Background Interleukin (IL)-11, a cytokine produced by breast cancer, has been implicated in breast cancer-induced osteolysis (bone destruction) but the mechanism(s) of action remain controversial.
McCoy Erin M +3 more
doaj +1 more source
Journal of Indian Society of Periodontology, 2015 Context: Interleukin-11 (IL-11) is a multifunctional cytokine with a probable regulatory role in the inflamed periodontal tissue. It has also been shown to inhibit the production of potent proinflammatory cytokines like tumor necrosis factor-alpha, IL-6 ...
Rohit Prasad +5 more
doaj +1 more source
Emerging roles for IL-11 signaling in cancer development and progression: Focus on breast cancer.
Cytokine & growth factor reviews, 2015 Interleukin (IL)-11 is a member of the IL-6 family of cytokines that is defined by the shared use of the GP130 signal transducing receptor subunit. In addition of its long recognized activities as a hemopoietic growth factor, IL-11 has an emerging role ...
Cameron N. Johnstone +3 more
semanticscholar +1 more source