Results 81 to 90 of about 7,897,153 (261)

Expression of interleukin-11 (IL-11) and IL-11 receptor α in human gastric carcinoma and IL-11 upregulates the invasive activity of human gastric carcinoma cells

International Journal of Oncology, 2007
Previous investigations have shown that interleukin-11 (IL-11) and the IL-11 receptor (IL-11R) have been correlated with the regulation of tumor progression, cellular growth and differentiation in several malignant tumors. The objectives of this study were to clarify the role of IL-11 and IL-11Ralpha in human gastric carcinoma.
Toshiyuki, Nakayama, Ayumi, Yoshizaki, Seiya, Izumida, Tomoyuki, Suehiro, Shiro, Miura, Takashi, Uemura, Yuichi, Yakata, Kazuko, Shichijo, Shunichi, Yamashita, Ichiro, Sekin   +9 more
openaire   +3 more sources

Improved Early Referral in Long‐Term Survivor Care With Institutional Standardized Practice Among Childhood Leukemia Survivors#

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In 2018, the Texas Children's Cancer and Hematology Center Leukemia Program implemented a practice standard to support the transition from treatment to survivorship that includes shared, alternating care between leukemia and survivorship clinicians and a reminder to refer survivors to the long‐term survivor clinic (LTSC) 2 years after ...
Ji Yun Tark, Kayla L. Foster, Omar Shakeel, Mary C. Shapiro, Shawki L. Qasim, ZoAnn Dreyer, Eric S. Schafer, Ashley M. Butler, Austin L. Brown, Maria Monica Gramatges   +9 more
wiley   +1 more source

A ligand peptide motif selected from a cancer patient is a receptor-interacting site within human interleukin-11. [PDF]

PLoS ONE, 2008
Interleukin-11 (IL-11) is a pleiotropic cytokine approved by the FDA against chemotherapy-induced thrombocytopenia. From a combinatorial selection in a cancer patient, we isolated an IL-11-like peptide mapping to domain I of the IL-11 (sequence CGRRAGGSC)
Marina Cardó-Vila, Amado J Zurita, Ricardo J Giordano, Jessica Sun, Roberto Rangel, Liliana Guzman-Rojas, Cristiane D Anobom, Ana P Valente, Fábio C L Almeida, Johanna Lahdenranta, Mikhail G Kolonin, Wadih Arap, Renata Pasqualini   +12 more
doaj   +1 more source

Expression of interleukin (IL)-11 and IL-11 receptor in human colorectal adenocarcinoma: IL-11 up-regulation of the invasive and proliferative activity of human colorectal carcinoma cells

International Journal of Oncology, 2006
Previous investigations have shown that interleukin (IL)-11/IL-11 receptor alpha-chain (IL-11Ralpha), a member of the PI3K, MAPK and JAK-STAT activating family of cytokines/receptors, correlates with the regulation of tumor progression. In this study, we established the IL-11/IL-11Ralpha expression profile in human colorectal adenocarcinoma (CRC) and ...
Ayumi, Yoshizaki, Toshiyuki, Nakayama, Kazuyuki, Yamazumi, Yuichi, Yakata, Mitsuru, Taba, Ichiro, Sekine   +5 more
openaire   +3 more sources

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source

Autocrine activation of JAK2 by IL-11 promotes platinum drug resistance

Oncogene, 2018
Antineoplastic platinum agents are used in first-line treatment of ovarian cancer, but treatment failure frequently results from platinum drug resistance.
Wei Zhou, Wei Sun, Mingo M H Yung, S. Dai, Yihua Cai, Chi-Wei Chen, Yunxiao Meng, Jennifer Lee, J. Braisted, Yinghua Xu, Noel Southall, P. Shinn, Xuefeng Huang, Zhangfa Song, Xiulei Chen, Yan Kai, Xin Cai, Zongzhu Li, Q. Hao, A. Cheung, H. Ngan, Stephanie S Liu, S. Barak, Jing Hao, Zhijun Dai, A. Tzatsos, Weiqun Peng, Huadong Pei, Zhiyong Han, D. Chan, Wei Zheng, Wenge Zhu   +31 more
semanticscholar   +1 more source

An [Imperfect] Case for Dyadic Research in Pediatric Psychosocial Oncology

Pediatric Blood &Cancer, EarlyView.
Stephanie M. Nanos, Lindsay A. Jibb, Gary Rodin   +2 more
wiley   +1 more source

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source

Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge, Maite E. Houwing, Rowena L. Grohssteiner, Ferdows Atiq, Sonja A. M. C. Teuben, Mirjam P. Fransen, Marjon H. Cnossen   +6 more
wiley   +1 more source

Long noncoding RNA HEGBC promotes tumorigenesis and metastasis of gallbladder cancer via forming a positive feedback loop with IL-11/STAT3 signaling pathway

Journal of experimental & clinical cancer research : CR, 2018
Gallbladder cancer (GBC) is a highly malignant cancer with poor prognosis. Several long noncoding RNAs (lncRNAs) have been reported to be involved in the tumorigenesis and progression of GBC. However, the expressions, clinical significances, and roles of
Liang Yang, QingXiang Gao, Xiaoxiong Wu, F. Feng, Kaiyun Xu   +4 more
semanticscholar   +1 more source