Results 231 to 240 of about 9,970,140 (285)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Involvement of IL-13-Induced Dysregulation of BDNF-NTRK2 Pathway in Symptoms of Eosinophilic Esophagitis. [PDF]

Allergy
Osonoi K, Sawada A, Maekawa Y, Yamaguchi M, Yamada S, Matsuyama K, Rochman M, Rothenberg ME, Han X, Matsuda N, Suzuki I, Tanaka F, Fujiwara Y, Shoda T.   +13 more
europepmc   +1 more source

Tra il "facchino" e il "filosofo" : "il terzo istruito"

, 2016
BINANTI, Luigino, Istruito, Tra il “facchino” e. il “filosofo”: il “Terzo   +1 more
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

A First-in-Human, Single- and Multiple-Dose Study of APG777, a Half-Life-Extended Anti-IL-13 Monoclonal Antibody, in Healthy Volunteers. [PDF]

Clin Transl Sci
Lim XQ, Winter E, Nograles K, Xu J, Zhang ZQ, Thankamony S, Dillinger L, Dambkowski CL.   +7 more
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Exploration of novel therapeutic targets for keloids based on clinical and molecular data: the role of the IL-4/IL-13 signaling pathway. [PDF]

Eur J Med Res
Li X, Lan J, Liu R, Lin T, Li Z, Cheng B.   +5 more
europepmc   +1 more source

IL-25-ILC2-IL-13 axis improves traumatic brain injury by mediating CXCL-10-dependent regulation of blood brain barrier integrity. [PDF]

J Neuroinflammation
Peng M, Shu D, Chen Z, Yang Z, Zhang M, Wang Q, Shao X.   +6 more
europepmc   +1 more source

Vascular Immune Crosstalk in COVID-19: RAAS Biomarker Signature Linking Angiotensin II to Respiratory Compromise and Soluble ACE2 to IL-13 and FGF, Revealing Therapeutic Targets. [PDF]

Int J Mol Sci
Fernandes TFB, Araujo IL, Vianna PHO, Bonomo AC, Pilotto JH, Côrtes FH, Morgado MG, Giacoia-Gripp CBW, De Sá NBR, Ribeiro-Alves M, Ribeiro MPD, Cardoso SW, Veloso VG, Grinsztejn B, Saraiva RM, De Almeida DV.   +15 more
europepmc   +1 more source

Serum IL-13 and IL-31 Levels are not Attenuated upon Dupilumab Treatment: Lessons from a Prospective Cohort.

Acta Derm Venereol
Suleiman G, Boyango I, Dawood M, Mirmovitch-Morvay O, Avitan-Hersh E.   +4 more
europepmc   +1 more source