Results 251 to 260 of about 1,581,460 (288)

Evaluation of the levels of interleukins IL-4, IL-13, IL-5, IL-10 and IL-33 in atopic dermatitis patients with and without dupilumab therapy. [PDF]

Front Immunol
Čelakovská J, Čermáková E, Boudková P, Krejsek J.   +3 more
europepmc   +1 more source

Interleukin-4 and -13 Gene Expression Profiles in Immune-Related Bullous Pemphigoid Indicate Efficacy of IL-4/IL-13 Inhibitors. [PDF]

Cancers (Basel)
Arnold L, Morak M, Kramer N, Berking C, Schefzyk M, Hassel JC, Ziemer M, French LE, Gutzmer R, Nashan D, Heinzerling L.   +10 more
europepmc   +1 more source

Tartaric Acid Exacerbates DSS-Induced Colitis by Promoting Eosinophilic Inflammation via IL-13 and IL-5Rα Upregulation. [PDF]

Pathogens
Riaz B, Ryu HM, Choi B, Sohn S.
europepmc   +1 more source

Comprehensive single-cell RNA-sequencing study of Tollip deficiency effect in IL-13-stimulated human airway epithelial cells. [PDF]

BMC Res Notes
Lee GY, Schaunaman N, Nouri HR, Kraft M, Chu HW.   +4 more
europepmc   +1 more source

Excretory/secretory products from Hymenolepis nana adult worms alleviate ulcerative colitis in mice via tuft/IL-13 signaling pathway. [PDF]

Parasit Vectors
Mou R, Cui X, Wang H, Zhang Z, Cheng Y, Wu W, Li J, Zhang K.   +7 more
europepmc   +1 more source

IL-13 and IL-13-induced periostin levels are specifically decreased in patients following endoscopic sinus surgery for chronic rhinosinusitis. [PDF]

J Allergy Clin Immunol
Harmon R, Schneider AL, Bai J, Racette SD, Reddy AT, Huang JH, Lehmann DS, Price CPE, Rodeghiero S, Agarwal A, Eide JG, Dong S, Conley DB, Welch KC, Kern RC, Shintani-Smith S, Peters AT, Kato A, Stevens WW, Muhammad LN, Schleimer RP, Tan BK.   +21 more
europepmc   +1 more source

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Role of periostin, FENO, IL-13, lebrikzumab, other IL-13 antagonist and dual IL-4/IL-13 antagonist in asthma

Expert Opinion on Biological Therapy, 2013
Asthma markedly diminishes quality of life due to limited activity, absences from work or school and hospitalizations. Patients with severe asthma which are not controlled despite taking effective therapy are most in need of new treatment approaches.
Swati, Agrawal, Robert G, Townley
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IL-13 Effector Functions

Annual Review of Immunology, 2003
IL-13 was first recognized for its effects on B cells and monocytes, where it upregulated class II expression, promoted IgE class switching and inhibited inflammatory cytokine production. It was also thought to be functionally redundant with IL-4. However, studies conducted with knockout mice, neutralizing antibodies, and novel antagonists demonstrate ...
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Genetics of IL-13 and functional relevance of IL-13 variants

Current Opinion in Allergy and Clinical Immunology, 2002
Studies in both humans and mice clearly show that interleukin (IL)-13 is a central regulator of allergic inflammation. Numerous single nucleotide polymorphisms have been recently identified in the IL-13 gene and have been found to be associated with allergic and/or asthmatic phenotypes in different populations throughout the world.
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Opposing roles for IL‐13 and IL‐13 receptor α2 in health and disease

Immunological Reviews, 2004
Summary:  Interleukin (IL)‐13 is a key inducer of several type‐2 cytokine‐dependent pathologies. It regulates inflammation, mucus production, tissue remodeling, and fibrosis. Consequently, it has become an important therapeutic target for a number of debilitating illnesses, including asthma, idiopathic pulmonary fibrosis, ulcerative colitis, as well as
Margaret M, Mentink-Kane, Thomas A, Wynn
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