Results 251 to 260 of about 1,572,209 (287)

IL-13 and IL-13-induced periostin levels are specifically decreased in patients following endoscopic sinus surgery for chronic rhinosinusitis. [PDF]

J Allergy Clin Immunol
Harmon R, Schneider AL, Bai J, Racette SD, Reddy AT, Huang JH, Lehmann DS, Price CPE, Rodeghiero S, Agarwal A, Eide JG, Dong S, Conley DB, Welch KC, Kern RC, Shintani-Smith S, Peters AT, Kato A, Stevens WW, Muhammad LN, Schleimer RP, Tan BK.   +21 more
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Club cell-derived brain-derived neurotrophic factor regulates murine airway mechanics and mucin production in response to IL-13 in a sex-dependent manner. [PDF]

Front Physiol
Fagan A, Sponchiado M, Mata L, Amin S, Aguirre JI, Prabhakaran S, Reznikov LR.   +6 more
europepmc   +1 more source

Leptin augments IL-13-induced airway eotaxins and submucosal eosinophilia in obesity-associated asthma. [PDF]

J Allergy Clin Immunol
Ingram JL, McQuade VL, Weiss J, Womble JT, Ihrie MD, Zhao K, Francisco D, Theriot B, May K, Kim H, McCravy M, Sauler M, Lugogo NL, Sunday ME, Everitt J, Walker JKL, Tighe RM, Kraft M, Que LG.   +18 more
europepmc   +1 more source

Gut-derived IL-13 contributes to growth via promoting hepatic IGF-1 production. [PDF]

Microbiome
Ma N, Wang H, Li Q, Chang M, Zhu J, Nan S, Zhang Q, Li Q, Yang D, Ming K, Zhuang S, Guo P, Yin R, Sun J, Wang H, Lei Q, Liu Z, Ding M, Zhou X, Ding Y.   +19 more
europepmc   +1 more source

Dietary zinc deficiency promotes Acinetobacter baumannii lung infection via IL-13 in mice. [PDF]

Nat Microbiol
Palmer LD, Traina KA, Juttukonda LJ, Lonergan ZR, Bansah DA, Ren X, Geary JH, Pinelli C, Boyd KL, Yang TS, Skaar EP.   +10 more
europepmc   +1 more source

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Role of periostin, FENO, IL-13, lebrikzumab, other IL-13 antagonist and dual IL-4/IL-13 antagonist in asthma

Expert Opinion on Biological Therapy, 2013
Asthma markedly diminishes quality of life due to limited activity, absences from work or school and hospitalizations. Patients with severe asthma which are not controlled despite taking effective therapy are most in need of new treatment approaches.
Swati, Agrawal, Robert G, Townley
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IL-13 Effector Functions

Annual Review of Immunology, 2003
IL-13 was first recognized for its effects on B cells and monocytes, where it upregulated class II expression, promoted IgE class switching and inhibited inflammatory cytokine production. It was also thought to be functionally redundant with IL-4. However, studies conducted with knockout mice, neutralizing antibodies, and novel antagonists demonstrate ...
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Genetics of IL-13 and functional relevance of IL-13 variants

Current Opinion in Allergy and Clinical Immunology, 2002
Studies in both humans and mice clearly show that interleukin (IL)-13 is a central regulator of allergic inflammation. Numerous single nucleotide polymorphisms have been recently identified in the IL-13 gene and have been found to be associated with allergic and/or asthmatic phenotypes in different populations throughout the world.
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Opposing roles for IL‐13 and IL‐13 receptor α2 in health and disease

Immunological Reviews, 2004
Summary:  Interleukin (IL)‐13 is a key inducer of several type‐2 cytokine‐dependent pathologies. It regulates inflammation, mucus production, tissue remodeling, and fibrosis. Consequently, it has become an important therapeutic target for a number of debilitating illnesses, including asthma, idiopathic pulmonary fibrosis, ulcerative colitis, as well as
Margaret M, Mentink-Kane, Thomas A, Wynn
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Polymorphisms of IL–13 and IL–4–IL–13–SNPs in patients with penicillins allergy

European Journal of Clinical Pharmacology, 2005
Although IL-4 and IL-13 share many biologic activities, some are unique to IL-13. We genotype the IL-13 and IL-4-IL-13-SNPs genes for polymorphisms that could then be used to determine associations with IgE regulation as well as levels of IL-4 and IL-13.Eight kinds of IgE specific to penicillins were determined with radioallergosorbent test (RAST) in ...
Jing, Yang, Hai-Ling, Qiao, Zi-Ming, Dong   +2 more
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