Results 251 to 260 of about 1,546,418 (287)

Dietary zinc deficiency promotes Acinetobacter baumannii lung infection via IL-13 in mice. [PDF]

Nat Microbiol
Palmer LD, Traina KA, Juttukonda LJ, Lonergan ZR, Bansah DA, Ren X, Geary JH, Pinelli C, Boyd KL, Yang TS, Skaar EP.   +10 more
europepmc   +1 more source

Adult Hymenolepis nana and its excretory-secretory products elicit mouse immune responses via tuft/IL-13 and FOXM1 signaling pathways. [PDF]

Parasit Vectors
Mou R, Cui XY, Luo YS, Cheng Y, Luo QY, Zhang ZF, Wu WL, Li JF, Zhang K.   +8 more
europepmc   +1 more source

Regulation of fibronectin and collagens type I, III and VI by TNF-α, TGF-β, IL-13, and tofacitinib. [PDF]

Sci Rep
Gillesberg FS, Pehrsson M, Bay-Jensen AC, Frederiksen P, Karsdal M, Deleuran BW, Kragstrup TW, Kubo S, Tanaka Y, Mortensen JH.   +9 more
europepmc   +1 more source

IL-4, IL-13, TNF-α and IFN-γ Downregulate CLDN8 Expression Through Activating JAK Signaling Pathway in HaCaT Cells. [PDF]

Clin Cosmet Investig Dermatol
Wang X, Mao D, Mu Z.
europepmc   +1 more source

IL-13 induces loss of CFTR in ionocytes and reduces airway epithelial fluid absorption. [PDF]

J Clin Invest
Romano Ibarra GS, Lei L, Yu W, Thurman AL, Gansemer ND, Meyerholz DK, Pezzulo AA, McCray PB, Thornell IM, Stoltz DA.   +9 more
europepmc   +1 more source

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Role of periostin, FENO, IL-13, lebrikzumab, other IL-13 antagonist and dual IL-4/IL-13 antagonist in asthma

Expert Opinion on Biological Therapy, 2013
Asthma markedly diminishes quality of life due to limited activity, absences from work or school and hospitalizations. Patients with severe asthma which are not controlled despite taking effective therapy are most in need of new treatment approaches.
Swati, Agrawal, Robert G, Townley
openaire   +2 more sources

IL-13 Effector Functions

Annual Review of Immunology, 2003
IL-13 was first recognized for its effects on B cells and monocytes, where it upregulated class II expression, promoted IgE class switching and inhibited inflammatory cytokine production. It was also thought to be functionally redundant with IL-4. However, studies conducted with knockout mice, neutralizing antibodies, and novel antagonists demonstrate ...
openaire   +2 more sources

Genetics of IL-13 and functional relevance of IL-13 variants

Current Opinion in Allergy and Clinical Immunology, 2002
Studies in both humans and mice clearly show that interleukin (IL)-13 is a central regulator of allergic inflammation. Numerous single nucleotide polymorphisms have been recently identified in the IL-13 gene and have been found to be associated with allergic and/or asthmatic phenotypes in different populations throughout the world.
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Opposing roles for IL‐13 and IL‐13 receptor α2 in health and disease

Immunological Reviews, 2004
Summary:  Interleukin (IL)‐13 is a key inducer of several type‐2 cytokine‐dependent pathologies. It regulates inflammation, mucus production, tissue remodeling, and fibrosis. Consequently, it has become an important therapeutic target for a number of debilitating illnesses, including asthma, idiopathic pulmonary fibrosis, ulcerative colitis, as well as
Margaret M, Mentink-Kane, Thomas A, Wynn
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Polymorphisms of IL–13 and IL–4–IL–13–SNPs in patients with penicillins allergy

European Journal of Clinical Pharmacology, 2005
Although IL-4 and IL-13 share many biologic activities, some are unique to IL-13. We genotype the IL-13 and IL-4-IL-13-SNPs genes for polymorphisms that could then be used to determine associations with IgE regulation as well as levels of IL-4 and IL-13.Eight kinds of IgE specific to penicillins were determined with radioallergosorbent test (RAST) in ...
Jing, Yang, Hai-Ling, Qiao, Zi-Ming, Dong   +2 more
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