Results 161 to 170 of about 1,433,889 (243)

Intestinal homeostasis alteration toward mucosal inflammation with blocking IL-17 in psoriasis patients: a case series. [PDF]

Transl Gastroenterol Hepatol
Shimodaira Y, Fukuda S, Takahashi S, Yamakawa T, Kono M, Iijima K.   +5 more
europepmc   +1 more source

IL-17 (IL-17A) [PDF]

Science-Business eXchange, 2011
openaire   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

IL-17-producing γδ T cells in the tumor microenvironment promote radioresistance in mice. [PDF]

J Clin Invest
Deng Y, Liu X, Yang X, Wei W, Wang J, Yang Z, Sun Y, Hu Y, Zhang H, Wang Y, Zhang Z, Wen L, Huang F, Yang K, Wan C.   +14 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Pharmacological Mechanisms of CheReCunJin Formula in Ameliorating Sjögren's Syndrome: Suppression of IL-17 Signal-Mediated Inflammatory Cascade. [PDF]

J Inflamm Res
Gan Y, Du L, Sun Y, Li F, Chen H, Yan S, Xiao X, Li S, Wu B.   +8 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Oxytocin Modulates Microglial IL-17-Linked Inflammatory Pathways Through the IL-6/COX-2. [PDF]

Life (Basel)
Hwang W, Jang YH, Hong J, Kang S, Hur JK, Lee HJ.   +5 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Expression and clinical significance of IL-17 and its receptor in bacterial pneumonia before and after treatment. [PDF]

Am J Transl Res
Zhang X, Zhou D, Chu J.
europepmc   +1 more source