Results 41 to 50 of about 1,433,889 (243)

Clinical utility of ixekizumab in the treatment of moderate-to-severe plaque psoriasis

Psoriasis: Targets and Therapy, 2017
Sahil Sekhon, Caleb Jeon, Mio Nakamura, Di Yan, Ladan Afifi, Tina Bhutani, Ethan Levin Department of Dermatology, University of California, San Francisco, San Francisco, CA, USA Abstract: Psoriasis vulgaris is a chronic ...
Sekhon S, Jeon C, Nakamura M, Yan D, Afifi L, Bhutani T, Levin E   +6 more
doaj  

Results of the Childhood Cancer and Leukaemia Group's United Kingdom Relapsed Wilms Tumour Trial

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The United Kingdom relapsed Wilms tumour (UKW‐R) trial aimed to improve the historically low survival rates after relapse of Wilms tumour (WT) through a prospective national risk‐stratified protocol. The trial also evaluated efficacy and toxicity of high‐dose melphalan.
Sucheta J. Vaidya, Veronica Moroz, Juliet Hale, Vesna Pavasovic, Rachel Hobson, Patricia Sartori, Daniel Saunders, Mark Powis, Gordan M. Vujanic, Stephen Baker, Kathy Pritchard‐Jones   +10 more
wiley   +1 more source

Evaluation Of Cytokines Changes In Patients Infected With Giardia lamblia In Comparison With Healthy Subjects [PDF]

پیاورد سلامت, 2012
Background and Aim: Human Giardisis infection is caused by the flagellate protozoa. Giardia lamblia, which lives in the small intestine, causing damage and may also cause gastrointestinal symptoms.
Mitra Zarebavani, Nasrin Dashti, Nahid Einollahi, Arezoo Jamali   +3 more
doaj   +1 more source

A Reappraisal on the Potential Ability of Human Neutrophils to Express and Produce IL-17 Family Members In Vitro: Failure to Reproducibly Detect It

Frontiers in Immunology, 2018
Neutrophils are known to perform a series of effector functions that are crucial for the innate and adaptive responses, including the synthesis and secretion of a variety of cytokines.
Nicola Tamassia, Fabio Arruda-Silva, Fabio Arruda-Silva, Federica Calzetti, Silvia Lonardi, Sara Gasperini, Elisa Gardiman, Francisco Bianchetto-Aguilera, Luisa Benerini Gatta, Giampiero Girolomoni, Alberto Mantovani, Alberto Mantovani, Alberto Mantovani, William Vermi, Marco A. Cassatella   +14 more
doaj   +1 more source

Salt, inflammation, IL‐17 and hypertension [PDF]

British Journal of Pharmacology, 2018
Traditionally, arterial hypertension and subsequent end‐organ damage have been attributed to haemodynamic factors, but increasing evidence indicates that inflammation also contributes to the deleterious consequences of this disease. The immune system has evolved to prevent invasion of foreign microorganisms and to promote tissue healing after injury ...
Ulrich O Wenzel, Marlies Bode, Christian Kurts, Heimo Ehmke   +3 more
openaire   +2 more sources

Exploring Preferences for a Digital Single‐Session Intervention for Adolescent Siblings of Youth With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Adolescent siblings of children with cancer are at elevated risk for psychosocial problems. Unfortunately, various barriers such as limited family time and resources, conflicting schedules, and psychosocial staffing constraints at cancer centers hinder sibling access to support.
Christina M. Amaro, Sarah Silver, Prishi Patel, Meredith K. Reffner Collins, Kimberly S. Canter, Stephanie Fooks‐Parker, Michael Amylon, Shawna V. Hudson, Jessica L. Schleider, Melissa A. Alderfer, Katie A. Devine   +10 more
wiley   +1 more source

Increased Levels of Interleukin-17A Exosomes in Psoriasis

Acta Dermato-Venereologica, 2019
Exosomes are involved in modulating the immune system and mediating communication between cells. The aim of this study was to investigate the involvement of exosomes in psoriasis.
Claire Jacquin-Porretaz, Marine Cordonnier, Charlée Nardin, Laura Boullerot, Gaetan Chanteloup, Valentin Vautrot, Olivier Adotevi, Carmen Garrido, Jessica Gobbo, François Aubin   +9 more
doaj   +1 more source

Regulatory effects of C5a on IL-17A, IL-17F, and IL-23

Frontiers in Immunology, 2013
The complement anaphylatoxin, C5a, through binding to its receptors (C5aR or C5L2), has important biological properties for recruitment and activation of phagocytes.
Jamison J. Grailer, Markus eBosmann, Peter A. Ward   +2 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Proinflammatory IL-17 induces iBALT development [PDF]

Cellular & Molecular Immunology, 2011
The development of secondary lymphoid organs (SLOs) and tertiary lymphoid organs (TLOs) share many common mechanisms. Molecules of the tumor necrosis factor family, especially lymphotoxin, and the lymphoid homeostatic chemokines, such as CXCL13, CCL19 and CCL21, play important roles in the development of both SLOs and TLOs.1, 2, 3 This may be ...
Mingzhao, Zhu, Yangxin, Fu
openaire   +2 more sources