Results 261 to 270 of about 1,536,578 (286)

Evidence for the expression of interleukin (IL)-18, IL-18 receptor and IL-18 binding protein in the human endometrium

MHR: Basic science of reproductive medicine, 2001
To see whether the interleukin (IL)-18 system is operative in the endometrium, we examined the expression of IL-18, IL-18 receptor (IL-18R) and IL-18 binding protein (IL-18BP), the substance known to neutralize IL-18 activity, in this tissue. Reverse transcription-polymerase chain reaction analyses showed that IL-18, IL-18R and IL-18BP mRNA were ...
O, Yoshino, Y, Osuga, K, Koga, O, Tsutsumi, T, Yano, T, Fujii, K, Kugu, M, Momoeda, T, Fujiwara, K, Tomita, Y, Taketani   +10 more
openaire   +2 more sources

[IL-18 and IL-18 receptor].

Nihon rinsho. Japanese journal of clinical medicine, 1998
Interleukin-18 (IL-18) is a recently cloned cytokine, produced from activated macrophages, including Kupffer cells. IL-18 is originally called interferon-gamma inducing factor (IGIF), due to its action to induce IFN-gamma production from Th 1 cells and NK cells.
S, Kashiwamura, H, Okamura
openaire   +1 more source

Expression of IL-18 in psoriasis

Archives of Dermatological Research, 2001
Interleukin-18 (IL-18) is a novel cytokine that plays an important role in the T-helper 1 (Th1) response, primarily via its ability to induce IFN-gamma production in T cells and NK cells. Human keratinocytes produce IL-18, as do monocytes and macrophages, which are the two major sources of this molecule.
Y, Ohta, Y, Hamada, K, Katsuoka
openaire   +2 more sources

Bovine Anterior Pituitary Progenitor Cell Line Expresses Interleukin (IL)‐18 and IL‐18 Receptor

Journal of Neuroendocrinology, 2008
In the anterior pituitary gland, inflammatory mediators regulate cell function through an immuno‐endocrine pathway. Recent studies have shown that undifferentiated stem cells act as immunomodulators. These studies prompted us to establish a progenitor cell line from the bovine anterior pituitary gland and to detail its function.
Y, Nagai, H, Ogasawara, Y, Taketa, H, Aso, S, Tanaka, T, Kanaya, K, Watanabe, S, Ohwada, Y, Muneta, T, Yamaguchi   +9 more
openaire   +2 more sources

Cellular localization of IL-18 and IL-18 receptor in pig anterior pituitary gland

Domestic Animal Endocrinology, 2006
Pro-inflammatory cytokine interleukin 18 (IL-18) has been proposed to have a role in modulating immuno-endocrine functions. Our previous study showed that IL-18 and IL-18 receptor (IL-18R) colocalized in somatotrophs of the bovine anterior pituitary gland, and the possibility that IL-18 acts on somatotrophs as an autocrine factor. In the present study,
Yasuhiro, Nagai, Kouichi, Watanabe, Hisashi, Aso, Shyuichi, Ohwada, Yoshihiro, Muneta, Takahiro, Yamaguchi   +5 more
openaire   +2 more sources

IL-18

Science-Business eXchange, 2012
G. Citerio, C. Giussani, Hugo Sax, Didier Pittet, Xiaoyan Wen, John A. Kellum, Angela M. Mills, Nova L. Panebianco, Stuart M. Flechner, Jean Carlet, Andie S. Lee, Stephan Jürgen Harbarth, Jason Ferries, Christian Sandrock, Daniel Scheurich, Hilary M. Babcock, Katherine Mandell, Gregory J. Jurkovich, Clay Cothren Burlew, Ernest E. Moore, Philip F. Stahel, Michael A. Flierl, Christoph E. Heyde, L. D. Britt, Howard R. Champion, Russ Hewson, Rupert M. Pearse, Martin Damm, Marcelo Gama de Abreu, Kevin W. Finkel, Manu L. N. G. Malbrain, Lewis J. Kaplan, J. Claude Hemphill, Jacob Freeman, Andrew M. Bauer, Daniel K. Resnick, Thomas Luecke, Jonathan I. Fischer, Anthony J. Dean, Christiane S. Hartog, Konrad Reinhart, Ryan P. Morrissey, Lewis S. Nelson   +42 more
  +4 more sources

Impact of IL-18 on inflammation.

Journal of biological regulators and homeostatic agents, 2011
IL-18 is produced by many cell types, such as Kupffer cells, keratinocytes, macrophages, dendritic cells, and activated T cells stimulated by LPS. It is an important regulator of both innate and acquired immune responses. IL-18 plays a central role in rheumatoid arthritis since the T cells and macrophages that invade the synovial. These finding support
Tripodi D, Maccauro G, Anogeianaki A, Castellani ML, Pandolfi F, Felaco P, Toniato E, De Lutiis MA, Fulcheri M, Tetè S, Galzio R, Salini V, CARAFFA, Auro, ANTINOLFI, PIERLUIGI, Frydas I, Sabatino G, Shaik Dasthagirisaheb YB   +16 more
openaire   +6 more sources

IL-18 in autoimmunity

2006
IL-18 is among the cytokines responsible for immune-mediated pathologies and is probably one of the factors that contribute to the pathogenesis of autoimmune diseases. Identification of the causes of uncontrolled IL-18 production and activity in autoimmunity would allow for novel therapeutic targets to effectively block autoimmune activation and ...
Boraschi D, Dinarello CA
openaire   +2 more sources

[Elevated IL-18, IL-18 binding protein and IL-18 receptor in eosinophil-enriched blood cells in patients with asthma].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2017
Objective To investigate the changes of interleukin-18 (IL-18), interleukin 18 binding protein (IL-18BP) and interleukin 18 receptor (IL-18R) expressions in eosinophil-enriched cells from asthmatic patients, and study the correlations among them. Methods Peripheral venous blood from asthmatic patients and normal subjects were collected and stimulated ...
Leilei, Yuan, Sijing, Lu, Huiyun, Zhang, Junling, Wang, Yalin, Hu, Ling, Wang, Shaoheng, He   +6 more
openaire   +1 more source

IL-18

2013
Wen Li, Yoshimasa Tanaka, Haruki Okamura
openaire   +1 more source