Results 91 to 100 of about 2,293,083 (280)
The IL-1 family cytokines and receptors in autoimmune diseases
Autoimmunity Reviews, 2020 The role of the cytokines and receptors of the IL-1 family in inflammation is well known. Several cytokines of the family have a powerful inflammatory activity, with IL-1β being the best-characterized factor. The inflammatory activity of IL-1 cytokines is regulated by other factors of the family, including receptor antagonists, soluble receptors and ...
Migliorini Paola +4 more
openaire +3 more sources
Aberrant Expression of Three New Members of IL-1 Family (IL-36α, IL-37 and IL-38) in Patients with Multiple Sclerosis [PDF]
Journal of Advanced Biomedical Sciences, 2023 Background & Objective: Multiple sclerosis (MS) is a neurodegenerative disease that is characterized by demyelination and neuronal dysfunction. The study of the expression of cytokine genes seems to be an appropriate option for assessing their potential ...
Forouzan Ahmadi Khoei +2 more
doaj
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Despite their increased risk for functional impairment resulting from cancer and its treatments, few adolescents and young adults (AYAs) with a hematological malignancy receive the recommended or therapeutic dose of exercise per week during inpatient hospitalizations.
Jennifer A. Kelleher +8 more
wiley +1 more source
Cell Reports, 2018 Summary: Neutrophil granule proteases are thought to function as anti-microbial effectors, cooperatively hydrolyzing microorganisms within phagosomes, or upon deployment into the extracellular space.
Danielle M. Clancy +7 more
doaj +1 more source
Interleukin-36 family as a novel regulator of inflammation in the barrier tissues
Медицинская иммунология, 2020 The interleukin-36 (IL-36) family was discerned in the superfamily of interleukin-1 (IL-1) ten years ago. This family includes three isoforms of IL-36α, IL-36β, IL-36γ, which have pro-inflammatory activity and a specific receptor antagonist, IL-36ra ...
S. V. Sennikova, A. P. Toptygina
doaj +1 more source
Identification of a gene for an ancient cytokine, interleukin 15-like, in mammals; interleukins 2 and 15 co-evolved with this third family member, all sharing binding motifs for IL-15Rα [PDF]
, 2013 Interleukins 2 and 15 (IL-2 and IL-15) are highly differentiated but related cytokines with overlapping, yet also distinct functions, and established benefits for medical drug use.
Dijkstra,JM +9 more
core +1 more source
Opposing functions of classic and novel IL-1 family members in gut health and disease
Frontiers in Immunology, 2013 In addition to their well-established role(s) in the pathogenesis of gastrointestinal (GI)-related inflammatory disorders, including inflammatory bowel disease (IBD) and inflammation-associated colorectal cancer (CRC), emerging evidence confirms the ...
Loris R. Lopetuso +4 more
doaj +1 more source
Full length interleukin 33 aggravates radiation-induced skin reaction [PDF]
, 2017 The interleukin (IL)-1 family member IL-33 has been described as intracellular alarmin with broad roles in wound healing, skin inflammation but also autoimmunity.
Adam, Susanne +13 more
core +3 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Psychological safety (PS) is essential for teamwork, communication, and patient safety in complex healthcare environments. In pediatric oncology, interprofessional collaboration occurs under high emotional and organizational demands. Low PS may increase stress, burnout, and adverse events.
Alexandros Rahn +4 more
wiley +1 more source
Cross-disease innate gene signature: Emerging diversity and abundance in RA comparing to SLE and SSc [PDF]
, 2019 Overactivation of the innate immune system together with the impaired downstream pathway of type I interferon-responding genes is a hallmark of rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and systemic sclerosis (SSc).
Fillerová, Regina +8 more
core +1 more source