IL-1 family cytokines trigger sterile inflammatory disease [PDF]
Frontiers in Immunology, 2012 Inflammation plays vital roles in protective responses against pathogens and tissue repair, however improper resolution of inflammatory networks is centrally involved in the pathogenesis of many acute and chronic diseases.
John R Lukens +2 more
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New insights in the immunobiology of IL 1 family members [PDF]
Frontiers in Immunology, 2013 The interleukin-1 (IL 1) family of ligands is associated with acute and chronic inflammation, and plays an essential role in the non-specific innate response to infection.
Frank Van De Veerdonk, Mihai eNetea
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IL-1 Family Cytokine Regulation of Vascular Permeability and Angiogenesis [PDF]
Frontiers in Immunology, 2019 The IL-1 family of cytokines are well-known for their primary role in initiating inflammatory responses both in response to and acting as danger signals.
Erin Fahey +4 more
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Editorial: IL-1 Family Members in Health and Disease [PDF]
Frontiers in Immunology, 2019 PUBLISHED cited By 0 In 1985, two distinct cDNAs encoding proteins sharing human Interleukin-1 (IL-1) activity were described, thus defining the first two members of the IL-1 family—IL-1α and IL-1β. These potent pro-inflammatory cytokines have been the subject of much research in the area of fever and inflammation, as well as for their roles in a ...
Elizabeth Brint +4 more
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The Roles of IL-1 Family Cytokines in the Pathogenesis of Systemic Sclerosis [PDF]
Frontiers in Immunology, 2019 The IL-1 family consists of 11 cytokines, 7 ligands with agonist activity (IL-1α, IL-1β, IL-18, IL-33, IL-36α, IL-36β, IL-36γ) and four members with antagonistic activities [IL-1 receptor antagonist (IL-1Ra), IL-36Ra, IL-37, IL-38].
Dan Xu, Rong Mu, Xiaofan Wei
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Role of IL-1 Family Cytokines IL-36, IL-37, IL-38 in Osteoarthritis and Rheumatoid Arthritis: A Comprehensive Review [PDF]
Journal of Inflammation ResearchYuan Xu, Jing-Yan Wang, Yang Zou, Xue-Wei Ma, Tian Meng College of Health Industry, Sichuan Tourism University, Chengdu, Sichuan, 610100, People’s Republic of ChinaCorrespondence: Yuan Xu, Email 230973159@qq.comAbstract: Inflammatory cytokines ...
Xu Y, Wang JY, Zou Y, Ma XW, Meng T
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Profiling the Course of Resolving vs. Persistent Inflammation in Human Monocytes: The Role of IL-1 Family Molecules [PDF]
Frontiers in Immunology, 2020 Monocytes and macrophages have a central role in all phases of an inflammatory reaction. To understanding the regulation of monocyte activation during a physiological or pathological inflammation, we propose two in vitro models that recapitulate the ...
Paola Italiani +6 more
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Analysis of the role of IL-1 family and related genes in head and neck squamous cell carcinoma [PDF]
Brazilian Journal of OtorhinolaryngologyObjective: The Interleukin-1 (IL-1) family plays an important regulatory role in the development of tumors, but its function is still unclear in head and neck squamous cell carcinoma (HNSCC).
Gaofei Yin +6 more
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Divergent Roles for the IL-1 Family in Gastrointestinal Homeostasis and Inflammation [PDF]
Frontiers in Immunology, 2019 Inflammatory disorders of the gastro-intestinal tract are a major cause of morbidity and significant burden from a health and economic perspective in industrialized countries.
Craig P. McEntee +5 more
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PGD2, IL-1-Family Members and Mast Cells [PDF]
European Journal of Inflammation, 2010 Cytokines are immunomodulatory and inflammatory compounds produced by many different cell types. The IL-1 family consists of at least eleven cytokines including IL-18 and IL-13 and are essential to the host defence against severe infections and mediate ...
A. Anogeianaki +15 more
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