Results 251 to 260 of about 2,293,083 (280)

A new nomenclature for IL-1-family genes

Trends in Immunology, 2001
of six novel members of the interleukin-1 (IL-1) gene family1–6 (see E. Dunn et al., pp. 533–536). The designation of these novel genes as relatives of the previously known family members encoding IL-1α, IL-1β, IL-1 receptor antagonist (IL-1ra) and IL-18 is based on their conservation of amino acid sequence, identity of gene structure, and (probable ...
John E Sims, Yang Pan, Dirk E Smith, Martin J.H Nicklin, Jenny L Barton, J.Fernando Bazan, Robert A Kastelein, Samantha J Busfield, John E Ford, Haishan Lin, Julio J Mulero, Sanjay Kumar, James (Guohua) Pan, Peter R Young   +13 more
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Association between the IL-1 family gene cluster and spondyloarthritis

Annals of the Rheumatic Diseases, 2012
Spondyloarthritis is a group of articular disorders sharing a genetic background. Polymorphisms in the IL-1 gene cluster have previously been associated with ankylosing spondylitis (AS), a subset of spondyloarthritis. This study examined the association between several of these polymorphisms and the whole spondyloarthritis.
Dominique, Monnet, Amir, Kadi, Brigitte, Izac, Nicolas, Lebrun, Franck, Letourneur, Elena, Zinovieva, Roula, Said-Nahal, Gilles, Chiocchia, Maxime, Breban   +8 more
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IL-1 Family Members in Inflammatory Skin Disease

2006
The cytokines IL-1α and IL-1β have long been known to play a profound role in inflammation, and in the past decade another cytokine, IL-18 (originally known as IGIF), has also been realized to be an IL-1 family member and to possess significant inflammatory activity.
J. Sims, J. Towne, H. Blumberg
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The role of IL-1 family cytokines in diabetic cardiomyopathy

Metabolism
Diabetic cardiomyopathy (DCM) is the primary cause of heart failure in patients with diabetes and is characterised by contractile dysfunction and left ventricular hypertrophy. The complex pathological and physiological mechanisms underlying DCM have contributed to a limited number of available treatment options.
Qi, Wu, Yan, Zeng, Kang, Geng, Man, Guo, Fang-Yuan, Teng, Pi-Jun, Yan, Yi, Lei, Yang, Long, Zong-Zhe, Jiang, Betty Yuen-Kwan, Law, Yong, Xu   +10 more
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The IL-1 family: The role of IL-1 and IL-18 in inflammation

2004
IL-1 and its related family member IL-18 are primarily proinflammatory cytokines by their ability to stimulate the expression of genes associated with inflammation and autoimmune diseases. The most salient and relevant properties of IL-1 in inflammation are the initiation of cyclooxygenase type 2 (COX-2), type 2 phospholipase A and inducible nitric ...
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IL-1 and IL-18 receptors, and their extended family

Current Opinion in Immunology, 2002
The cytokines IL-1 and IL-18 are key molecules in both the innate and the adaptive immune response. Recently, important insights have been gained into the regulation of their functions. Moreover, it has become apparent that they are members of a larger family of related receptors, some of which can also be shown to contribute to host defense.
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The IL-1 family and inflammatory diseases.

Clinical and experimental rheumatology, 2004
IL-1 and its related family member IL-18 are primarily proinflammatory cytokines by their ability to stimulate the expression of genes associated with inflammation and autoimmune diseases. For IL-1 (IL-1alpha and IL-1beta), the most salient and relevant properties are the initiation of cyclooxygenase type 2 (COX-2), type 2 phospholipase A and inducible
openaire   +1 more source

11 IL-1 family members in inflammatory skin disease.

Ernst Schering Research Foundation workshop, 2006
The cytokines IL-1alpha and IL-1beta have long been known to play a profound role in inflammation, and in the past decade another cytokine, IL-18 (originally known as IGIF), has also been realized to be an IL-1 family member and to possess significant inflammatory activity.
J, Sims, J, Towne, H, Blumberg
openaire   +1 more source

Genetic testing in prostate cancer management: Considerations informing primary care

Ca-A Cancer Journal for Clinicians, 2022
Veda N Giri, Jacob E Berchuck, Mary-Ellen Taplin   +2 more
exaly  

IL-1 family nomenclature (vol 11, pg 973, 2010)

2011
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Dinarello Charles, Arend William, Sims John, Smith Dirk, Blumberg Hal, O'Neill Luke, GoldbachMansky Raphaela, Pizarro Theresa, Hoffman H, Bufler Philip, Nold Marcel, Ghezzi Pietro, Mantovani Alberto, Garlanda Cecilia, Boraschi Diana, Rubartelli Anna, Netea Mihai, van der Meer Jos, Joosten Leo, MandrupPoulsen Tom, Donath Marc, Lewis Eli, Pfeilschifter Josef, Martin Michael, Kracht Michael, Muehl H, Novick Daniela, Lukic Miodrag, Conti Bruno, Solinger Alan, Kelk Peyman, van de Veerdonk Frank, Gabel Chiristopher   +32 more
openaire   +2 more sources