Results 91 to 100 of about 65,138,242 (275)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose To explore caregivers' experiences and perceptions of the nutritional challenges faced by children and adolescents undergoing cancer treatment, including oral intake and the use of nutritional support. Methods This was a qualitative study based on focus groups with parents and caregivers at a Brazilian pediatric oncology hospital ...
Danyelle Apparecida Balsamão Marques +5 more
wiley +1 more source
IL-21 effects on newly EBV infected primary B-cell EBNA2 target gene CD23 expression.
(A) Immunoblot analysis of WCL from primary human B cells at 7 DPI, which were then mock treated or stimulated with IL-21 for six days. (B) Immunoblot analysis of WCL from primary B cells at 10 DPI, mock treated or treated with IL-15 or IL-21 for six ...
Ethel Cesarman (57730) +5 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT The medical burdens of sickle cell disease (SCD) and transfusion‐dependent β‐thalassemia (TDT) are chronic and cumulative, even in children. Yet the effects expand beyond medications and healthcare visits due to their impacts on school attendance, academic performance, and peer engagement.
Mary Ann Etling +2 more
wiley +1 more source
Exhausted signature and regulatory network of NK cells in myasthenia gravis
Frontiers in ImmunologyIntroductionNK cells are dysfunctional in myasthenia gravis (MG), but the mechanism is unclear. This study aims to measure associations and underlying mechanisms between the NK cells and the development of MG.MethodsTwenty healthy controls (HCs) and 53 ...
Qing Zhang +15 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Heavy menstrual bleeding (HMB) is a common condition among adolescents and young adults (AYAs) and is the leading cause of iron deficiency anemia (IDA) in this population. Growing evidence suggests that social determinants of health (SDOH) influence menstrual bleeding patterns, access to care, and treatment. However, no studies have
Maria Carter‐Febres +6 more
wiley +1 more source
Mycobacterium tuberculosis-Specific IL-21+IFN-γ+CD4+ T Cells Are Regulated by IL-12. [PDF]
, 2016 In the current study of Mycobacterium tuberculosis (MTB)-specific T and B cells, we found that MTB-specific peptides from early secreted antigenic target-6 (ESAT-6) and culture filtrate protein-10 (CFP-10) induced the expression of IL-21 predominantly in
Suihua Lao +6 more
core +1 more source
Iranian Journal of Allergy, Asthma and Immunology, 2018 Asthma prevalence and severity are greater in women than in men, and mounting evidence suggests this is in part related to female steroid sex hormones. Conflicting data are reported regarding pro- and anti-inflammatory properties of estradiol. This study
Abbas Ahmadi-Vasmehjani +5 more
doaj
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye +33 more
wiley +1 more source
In vitro stimulation of purified naïve CD4 T cells with IL-6 or IL-21 drives high IL-21 expression.
, 2013 (A–D) Naïve sorted CD4 T cells (CD4+CD44−NK1.1−CD25−) were stimulated for 3 days on αCD3/αCD28 coated plates in the presence of αIFNγ, αIL-4, and αTGFβ (Th0) ± IL-6 or IL-21.
Burton Barnett (354729) +7 more
core +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola +4 more
wiley +1 more source