Results 71 to 80 of about 65,138,242 (275)

Higher efficacy of anti-IL-6/IL-21 combination therapy compared to monotherapy in the induction phase of Th17-driven experimental arthritis [PDF]

, 2017
Contains fulltext : 173198.pdf (Publisher’s version ) (Open Access)Th17 cells and their cytokines are linked to the pathogenesis of rheumatoid arthritis, a chronic autoimmune disease characterized by joint inflammation. Th17 development
Wim B. van den Berg (118337), Marijnissen, Renoud J., Walgreen, B., Peter L van Lent, van den Bersselaar, Liduine, Liduine van den Bersselaar (3716074), Helsen, Monique M., van de Loo, Fons A., Walgreen, Birgitte, Birgitte Walgreen, van Lent, Peter L., Lent, P.L.E.M. van, van der Kraan, Peter M., Renoud J. Marijnissen (158623), Roeleveld, Debbie M., Monique M Helsen, Marije I. Koenders (158627), Loo, F.A. van de, Fons A van de Loo, Birgitte Walgreen (3716071), Fons A. van de Loo (118339), Peter M. van der Kraan (714850), Kraan, P.M. van der, Renoud J Marijnissen, Peter L. van Lent (384303), Peter M van der Kraan, Berg, W.B. van den, Koenders, Marije I., Koenders, M.I., Wim B van den Berg, Bersselaar, L.A.M. van den, Liduine van den Bersselaar, Monique M. Helsen (3716077), Roeleveld, D.M., Debbie M Roeleveld, van den Berg, Wim B., Marije I Koenders, Marijnissen, R.J., Helsen, M.M.A., Debbie M. Roeleveld (3716080), Walgreen Birgitte, van den Berg Wim B., van Lent Peter L., van den Bersselaar Liduine, Roeleveld Debbie M., Marijnissen Renoud J., van de Loo Fons A., Helsen Monique M., van der Kraan Peter M., Koenders Marije I.   +49 more
core   +1 more source

Parents of Youth With Cancer Report on Their Psychosocial Care: iSTEPPP Survey Finds Alignment and Gaps With Standards

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families guide the provision of comprehensive psychosocial care. Parallel to research characterizing implementation of the Standards from the perspective of providers, this study examines implementation of the Standards from the perspective of parents of youth ...
Emily M. Pariseau, Kimberly Buff, Michele A. Scialla, Kimberly S. Canter, Lori Wiener, Victoria Sardi‐Brown, Julia B. Tager, Kamyar Arasteh, Anne E. Kazak   +8 more
wiley   +1 more source

CD4+ T Cells of Myasthenia Gravis Patients Are Characterized by Increased IL-21, IL-4, and IL-17A Productions and Higher Presence of PD-1 and ICOS

Frontiers in Immunology, 2020
Myasthenia gravis (MG) is an autoimmune disease mediated by autoantibodies predominantly against the acetylcholine receptor (AChR). Specific T cell subsets are required for long-term antibody responses, and cytokines secreted mainly from CD4+ T cells ...
Merve Çebi, Hacer Durmus, Fikret Aysal, Berker Özkan, Gizem Engin Gül, Arman Çakar, Mehmet Hocaoglu, Metin Mercan, Sibel P. Yentür, Melih Tütüncü, Vildan Yayla, Onur Akan, Öner Dogan, Yeşim Parman, Güher Saruhan-Direskeneli   +14 more
doaj   +1 more source

Assessment of sequence homology and immunologic cross-reactivity between tree shrew (Tupaia belangeri) and human IL-21. [PDF]

PLoS ONE, 2017
Many studies have indicated that the expression of interleukin-21 (IL-21) is associated with the pathogenesis of certain liver diseases. However, in alternative animal models of liver diseases, it remains unknown whether the tree shrew could be utilized ...
Rong Ding, Hui Zhang, Lihong Zhang, Wenwen Zhao, Yongyin Li, Jianyong Yang, Yuanxu Zhang, Shiwu Ma   +7 more
doaj   +1 more source

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess, Gustaf Glavå, Simon Skau, Hans‐Georg Kuhn, Maria Bäck, Marianne Jarfelt   +5 more
wiley   +1 more source

Autocrine regulation of IL-21 production in human T lymphocytes [PDF]

, 2008
IL-21 has pathologic function in immune-inflammatory diseases. IL-21 mediates its functions through a heterodimeric receptor, composed of a specific subunit, termed IL-21R, and the common gamma-chain.
PALLONE, FRANCESCO, Fina, D, G. Monteleone, MONTELEONE, GIOVANNI, M. Sarra, D. Fina, C. Stolfi, Stolfi, C, R. Caruso, Sica, G, G. Sica, MacDonald, TT, Caprioli, F, Caruso, R, SICA, GIUSEPPE, Monteleone, G, T. T. MacDonald, Pallone, F, F.A. Caprioli, F. Pallone, Sarra, M   +20 more
core   +1 more source

“We Cannot Talk as a Family”: Complexities of Survivorship Communication Among Hispanic/Latino Young Adult Survivors of Childhood Cancer, Parents, and Clinicians

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Young adult childhood cancer survivors (YA‐CCS) have an increased risk of treatment‐related health complications throughout their lives. Lifelong survivorship care is recommended, yet many YA‐CCS experience disruptions in care during pediatric‐to‐adult transitions and do not receive recommended survivorship care.
Kevin Shanchen Pu, Nicole Fernández‐Viña, Briana C. Martin‐Villa, Daniela Ramirez, Rebecca M. Lewinsohn, Mary Smith, Heidi Boynton, Lidia Schapira, Stephanie M. Smith   +8 more
wiley   +1 more source

Expression of KIR repertoire after culture of NK cells with IL-2 or IL-15 with/without IL-21

, 2011
Copyright information:Taken from "The proinflammatory cytokines IL-2, IL-15 and IL-21 modulate the repertoire of mature human natural killer cell receptors"http://arthritis-research.com/content/9/6/R125Arthritis Research & Therapy 2007;9(6):R125-R125 ...
Jean Villard (41257), Casimir de Rham (41253), Jean-Michel Dayer (10915), Sabrina Jendly (41255), Gregory Schneiter (41256), Sylvie Ferrari-Lacraz (41254)   +5 more
core   +1 more source

Increased serum concentrations of IL-1 beta, IL-21 and Th17 cells in overweight patients with rheumatoid arthritis

Arthritis Research & Therapy, 2017
Backgrounds Obesity is associated with worse disease activity and drug responses in patients with rheumatoid arthritis (RA). However, the immunological mechanisms responsible for the relationship between RA and obesity have not yet been clarified in ...
Hirofumi Shoda, Yasuo Nagafuchi, Yumi Tsuchida, Keiichi Sakurai, Shuji Sumitomo, Keishi Fujio, Kazuhiko Yamamoto   +6 more
doaj   +1 more source