Results 151 to 160 of about 1,415,739 (335)

IL-23; IL-23 receptor [PDF]

open access: yesScience-Business eXchange, 2012
openaire   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

The relation of cytokines of IL-17/IL-23 axis to Th1/Th2 cytokines and disease activity in systemic lupus erythematosus [PDF]

open access: yes, 2010
INTRODUCTION: Interleukin (IL)-17 is recently linked to the pathogenesis of systemic lupus erythematosus (SLE) but its relation to disease activity has not been well characterised.
Lo, Y, Mok, MY, Wu, H
core  

W1257 The Arg381gln SNP in IL 23 R Does Not Influence Response to Immunomodulators in Ulcerative Colitis or Crohn's Disease

open access: bronze, 2008
Bijay Baburajan   +8 more
openalex   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

IL-23 Inhibitors for Moderate-to-Severe Plaque Psoriasis: A Review of Clinical Efficacy, Safety, and Tolerability

open access: yesEuropean Medical Journal Dermatology, 2019
Psoriasis is a chronic, immune-mediated skin condition with systemic involvement, frequently requiring long-term treatment. At present, there are 11 biologic agents available for the treatment of moderate-to-severe psoriasis, which target specific ...
Sima D. Amin   +4 more
doaj  

Pierre Jeanneret _ Progetti per Chandigarh [PDF]

open access: yes, 2009
gli studenti che intendono frequentare il corso opzionale (V° anno) "architettura e città della contemporaneità" tenuto dalla prof.ssa maristella casciato, sono pregati di inviare, entro il 23/02/2009, un messaggio email che esprima il loro interesse, a:
Casciato, Maristella
core  

Supplementary Figure 2 from Combined Anti-CD40 and Anti–IL-23 Monoclonal Antibody Therapy Effectively Suppresses Tumor Growth and Metastases

open access: gold, 2023
Bianca von Scheidt   +6 more
openalex   +1 more source

From Bed to Bench and Back: TNF-α, IL-23/IL-17A, and JAK-Dependent Inflammation in the Pathogenesis of Psoriatic Synovitis [PDF]

open access: gold, 2021
Ettore Silvagni   +10 more
openalex   +1 more source

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