Results 171 to 180 of about 1,415,739 (335)

Novel anti-arthritic mechanisms of trans-cinnamaldehyde against complete Freund’s adjuvant-induced arthritis in mice: involvement of NF-кB/TNF-α and IL-6/IL-23/ IL-17 pathways in the immuno-inflammatory responses [PDF]

, 2022
Ghada S. El‐Tanbouly, Rehab S. Abdelrahman   +1 more
openalex   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Impact of IL-23 in prostate cancer

Asian Journal of Andrology, 2022
openaire   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

IL-22 Production Is Regulated by IL-23 During Listeria monocytogenes Infection but Is Not Required for Bacterial Clearance or Tissue Protection

, 2011
Amy C. Graham, Karen D. Carr, Amy N. Sieve, Mohanalaxmi Indramohan, Timothy J. Break, Rance E. Berg   +5 more
openalex   +2 more sources

IL-21/23 axis modulates inflammatory cytokines and RANKL expression in RA CD4 ⁺ T cells via p-Akt signaling [PDF]

, 2023
Gargee Bhattacharya, Soumya Sengupta, Rohila Jha, Shubham K. Shaw, Gajendra M. Jogdand, Prakash K. Barik, Prasanta Padhan, Jyoti Ranjan Parida, Satish Devadas   +8 more
openalex   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

23. PULCINELLA PRESENTA IL PUTIPÙ

Babel: Littératures Plurielles, 2017
Camillo De Felice
doaj   +1 more source

HMGB1 regulates Th17 cell differentiation and function in patients with psoriasis

Immunity, Inflammation and Disease
Background Psoriasis is an immune‐mediated chronic inflammatory skin disease, in which T helper 17 (Th17) cells and its effective cytokine interleukin (IL)‐17A play a pivotal pathogenic role.
Xiaofeng Zhu, Yue Dou, Yawen Lin, Gaoping Chu, Jing Wang, Lei Ma   +5 more
doaj   +1 more source

IL-23; CD40 [PDF]

Science-Business eXchange, 2014
openaire   +1 more source