Results 161 to 170 of about 1,415,739 (335)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A Th1 but not a Th17 response is present in the gastrointestinal involvement of Behçet's disease [PDF]

open access: yes, 2010
OBJECTIVES: Behçet's disease has been historically classified as a Th1 disease. The recently described IL-17/IL-23 pathway seems to play an important role in many inflammatory diseases and in the intestinal abnormalities of AS and CD.
CICCIA, Francesco   +6 more
core  

The IL-23/Th17 Axis in the Immunopathogenesis of Psoriasis [PDF]

open access: bronze, 2009
Antonella Di Cesare   +2 more
openalex   +1 more source

IL-23 [PDF]

open access: yesScience-Business eXchange, 2014
openaire   +1 more source

IL-23 and Th17 cells in infections and psoriasis

open access: yesJapanese Journal of Clinical Immunology, 2011
IL-23 is produced by dendritic cells, and other antigen presenting cells. IL-23 is required for the induction, expansion, maintenance and downstream effector functions of Th17 cells. Th17 cells upregulate neutrophil chemokines, antimicrobial peptides, and other pro-inflammatory cytokines.
openaire   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

IL-22–producing neutrophils contribute to antimicrobial defense and restitution of colonic epithelial integrity during colitis [PDF]

open access: yes, 2013
IL-22 plays an important role in mucosal epithelial cell homeostasis. Using a dextran sodium sulfate-induced mouse model of acute colitis, we observed an IL-23–dependent up-regulation of IL-22 in the middle and distal colon at the onset of epithelial ...
Chaplin, David D.   +7 more
core  

IL-23 Receptor Regulation by Let-7f in Human CD4+ Memory T Cells [PDF]

open access: bronze, 2011
Zhaoxia Li   +3 more
openalex   +1 more source

Home - About - Disclaimer - Privacy