Intelectin contributes to allergen-induced IL-25, IL-33 and TSLP expression and type 2 response in asthma and atopic dermatitis [PDF]
Mucosal Immunology, 2017 The epithelial and epidermal innate cytokines IL-25, IL-33, and thymic stromal lymphopoietin (TSLP) have pivotal roles in the initiation of allergic inflammation in asthma and atopic dermatitis (AD).
L. Yi +12 more
semanticscholar +3 more sources
IL-25 blockade inhibits metastasis in breast cancer [PDF]
Protein & Cell, 2016 Metastasis is the leading cause of death in breast cancer patients. However, the mechanisms underlying metastasis are not well understood and there is no effective treatment in the clinic.
Zhujun Jiang +5 more
doaj +3 more sources
Intestinal IL-25 prevents high-fat diet-induced obesity by modulating the cholesterol transporter NPC1L1 expression in the intestinal epithelial cells [PDF]
Scientific ReportsThe intestine is essential for digestion and nutrient absorption, and its altered function contributes to metabolic dysregulation and obesity-induced intestinal inflammation.
Siranart Jeerawattanawart +1 more
doaj +2 more sources
IL-1β suppresses innate IL-25 and IL-33 production and maintains helminth chronicity. [PDF]
PLoS Pathogens, 2013 Approximately 2 billion people currently suffer from intestinal helminth infections, which are typically chronic in nature and result in growth retardation, vitamin A deficiency, anemia and poor cognitive function.
Mario M Zaiss +5 more
doaj +5 more sources
Медицинская иммунология, 2021 Atopic dermatitis is one of the most common chronic inflammatory skin diseases caused by both terminal defects in keratinocyte differentiation, and pronounced type 2 immune responses.
M. B. Drozhdina, E. V. Suslova
doaj +1 more source
Interleukin 25 and its biological features and function in intestinal diseases
Central European Journal of Immunology, 2023 Interleukin 25 (IL-25), also known as IL-17E, is a member of the IL-17 cytokine family and an important regulator of the type 2 immune response. Accumulating evidence suggests that IL-25 interacts with diverse immune as well as non-immune cells and plays
Wei Jiang +3 more
doaj +1 more source
Epithelial cell alarmin cytokines: Frontline mediators of the asthma inflammatory response
Frontiers in Immunology, 2022 The exposure of the airway epithelium to external stimuli such as allergens, microbes, and air pollution triggers the release of the alarmin cytokines IL-25, IL-33 and thymic stromal lymphopoietin (TSLP). IL-25, IL-33 and TSLP interact with their ligands,
Marc Duchesne, Isobel Okoye, Paige Lacy
doaj +1 more source
Konsep Demokrasi Politik Dalam Islam [PDF]
, 2015 Coexistence of chronic rhinosinusitis (CRS) with asthma appears to impair asthma control. Type-2 innate lymphoid cells (ILC2s) respond to the cytokines of thymic stromal lymphopoietin (TSLP), interleukin (IL)-25 and IL-33, thus contributing to airway ...
Chi-Che Huang +9 more
core +12 more sources
Differential Effects of Alarmins on Human and Mouse Basophils
Frontiers in Immunology, 2022 Epithelial-derived alarmins (IL-33, TSLP, and IL-25) play an upstream role in the pathogenesis of asthma. Basophil-derived cytokines are a pivotal component of allergic inflammation.
Adriana R. Gambardella +17 more
doaj +1 more source
Interleukin‐25: New perspective and state‐of‐the‐art in cancer prognosis and treatment approaches
Cancer Medicine, 2021 Cancer is a leading cause of death which imposes a substantial financial burden. Among the several mechanisms involved in cancer progression, imbalance of immune cell‐derived factors such as cytokines and chemokines plays a central role.
Arezoo Gowhari Shabgah +7 more
doaj +1 more source