Results 31 to 40 of about 1,495,481 (236)

Regulation of IL-9 expression by IL-25 signaling [PDF]

Nature Immunology, 2010
The physiological regulation of the expression of interleukin (IL)-9, a cytokine traditionally regarded as being T(H)2 associated, remains unclear. Here, we show that IL-9-expressing T cells generated in vitro in the presence of transforming growth factor-beta and IL-4 express high levels of mRNA for IL-17 receptor B (IL-17RB), the receptor for IL-25 ...
Angkasekwinai, Pornpimon, Chang, Seon Hee, Thapa, Manoj, Watarai, Hiroshi, Dong, Chen   +4 more
openaire   +2 more sources

Street and Urban Muralism in Public Art: Conservation Between Evolution and Research in the Methods of the Istituto Centrale per Il Restauro

Heritage
This paper presents an overview of a research line developed at the Istituto Centrale per il Restauro within the CHANGES (Cultural Heritage Active Innovation for Next-Gen Sustainable Society) project, funded under the Italian National Recovery and ...
Paola Mezzadri, Sara De Angelis, Rebecca Picca Orlandi, Michela Renna, Giancarlo Sidoti   +4 more
doaj   +1 more source

New insights into the function of Interleukin-25 in disease pathogenesis

Biomarker Research, 2023
Interleukin-25 (IL-25), also known as IL-17E, is a cytokine belonging to the IL-17 family. IL-25 is abundantly expressed by Th2 cells and various kinds of epithelial cells.
Qingfang Yuan, Na Peng, Fan Xiao, Xiaofei Shi, Bo Zhu, Ke Rui, Jie Tian, Liwei Lu   +7 more
doaj   +1 more source

Revisiting the interleukin 17 family of cytokines in psoriasis: pathogenesis and potential targets for innovative therapies

Frontiers in Immunology, 2023
Psoriasis is a common chronic inflammatory skin disease, associated with substantial comorbidity. TH17 lymphocytes, differentiating under the influence of dendritic cell-derived IL-23, and mediating their effects via IL-17A, are believed to be central ...
Nicolo Costantino Brembilla, Wolf-Henning Boehncke, Wolf-Henning Boehncke   +2 more
doaj   +1 more source

Breast cancer therapy with IL-25 [PDF]

Science-Business eXchange, 2011
A U.S.-Taiwan team has shown that the proinflammatory cytokine IL-25 exerts potent cytotoxic effects in breast cancer cells and decreases mammary tumor growth in mice. The researchers and an undisclosed company will collaborate to develop systems for delivering IL-25 or its mimetics directly to tumors.
openaire   +1 more source

Synthetic small interfering RNAs selectively suppress the expression of proinflammatory cytokine genes (IL-25 and TSLP) in experiments in vitro

Медицинская иммунология
Allergic rhinitis (AR) is an inflammatory disease of the upper respiratory tract (nasal mucosa). AR affects up to 40% of the world’s population; in the Russian Federation, the incidence is 18% to 30%, depending on the region.
M. M. Kaganova, I. P. Shilovskiy, E. D. Timotievich, K. V. Yumashev, D. A. Gurskii, K. V. Vinogradova, M. V. Popova, M. R. Khaitov   +7 more
doaj   +1 more source

IL-25 Inhibits Atherosclerosis Development in Apolipoprotein E Deficient Mice [PDF]

PLOS ONE, 2015
IL-25 has been implicated in the initiation of type 2 immunity and in the protection against autoimmune inflammatory diseases. Recent studies have identified the novel innate lymphoid type 2 cells (ILC2s) as an IL-25 target cell population. The purpose of this study was to evaluate if IL-25 has any influence on atherosclerosis development in mice ...
Mantani, Polyxeni T., Duner, Pontus, Bengtsson, Eva, Alm, Ragnar, Ljungcrantz, Irena, Söderberg, Ingrid, Sundius, Lena, To, Fong, Nilsson, Jan, Björkbacka, Harry, Nordin Fredrikson, Gunilla   +10 more
openaire   +7 more sources

The Role of Airway Epithelial Cell Alarmins in Asthma

Cells, 2022
The airway epithelium is the first line of defense for the lungs, detecting inhaled environmental threats through pattern recognition receptors expressed transmembrane or intracellularly.
Christiane E. Whetstone, Maral Ranjbar, Hafsa Omer, Ruth P. Cusack, Gail M. Gauvreau   +4 more
doaj   +1 more source

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele, Calogero Virgone, Michaela Kuhlen, Sabine Irtan, Yves Reguerre, Malgorzata Krawczyk, Ewa Bien, Tal Ben‐Ami, Maja Cesen, Ricardo Lopez‐Almaraz, Andrea Ferrari, Gianni Bisogno, Dominik T. Schneider, Abbas Agaimy, Constantin Lapa, Hubert Ducou le Pointe, Rainer Claus, Catherine Daniel, Ines B. Brecht, Daniel Orbach   +19 more
wiley   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source