Results 51 to 60 of about 6,883,971 (302)
Group 2 Innate Lymphoid Cells Are Redundant in Experimental Renal Ischemia-Reperfusion Injury. [PDF]
, 2019 Acute kidney injury (AKI) can be fatal and is a well-defined risk factor for the development of chronic kidney disease. Group 2 innate lymphoid cells (ILC2s) are innate producers of type-2 cytokines and are critical regulators of homeostasis in ...
Cameron, Guy JM +9 more
core +4 more sources
IL-25 regulates Th17 function in autoimmune inflammation [PDF]
The Journal of Experimental Medicine, 2007 Interleukin (IL)-25 is a member of the IL-17 family of cytokines. However, unlike the other members of this family, IL-25 promotes T helper (Th) 2 responses. We now show that IL-25 also regulates the development of autoimmune inflammation mediated by IL-17–producing T cells.
Kleinschek, Melanie A. +11 more
openaire +2 more sources
Codon optimization, expression, purification, and functional characterization of recombinant human IL-25 in Pichia pastoris [PDF]
, 2013 Interleukin (IL)-25 (also known as IL-17E) is a distinct member of the IL-17 cytokine family which induces IL-4, IL-5, and IL-13 expression and promotes pathogenic T helper (Th)-2 cell responses in various organs.
Chengsheng Wu +4 more
core +1 more source
Type 2 Innate Lymphoid Cells in Allergic Disease. [PDF]
, 2013 Type II innate lymphoid cells (ILC2) are a novel population of lineage-negative cells that produce high levels of Th2 cytokines IL-5 and IL-13. ILC2 are found in human respiratory and gastrointestinal tissue as well as in skin.
Doherty, Taylor A +2 more
core +2 more sources
Evaluation of Sensitivity and Specificity of Interleukins 25 and 33 in Diagnosis of Pediatric Asthma
Journal of Pure and Applied Microbiology, 2021 The roles of interleukin 25 (a member of the interleukin 17 family) and interleukin 33 (a member of the interleukin 1 family) in asthma and airway hyperresponsiveness are yet to be fully understood.
Abeer Thaher Naji AL-Hasnawi
doaj +1 more source
OncoImmunology, 2018 Interleukin (IL)-25, a member of the IL-17 cytokine superfamily, is produced by immune and non-immune cells and exerts type 2 pro-inflammatory effects in vitro and in vivo. The IL-25 receptor(R) is composed of the IL-17RA/IL-17RB subunits.
Elisa Ferretti +9 more
doaj +1 more source
The IL-17 Family of Cytokines in Psoriasis: IL-17A and Beyond
Frontiers in Immunology, 2018 Psoriasis is a frequent chronic inflammatory skin disease, nowadays considered a major global health problem. Several new drugs, targeting the IL-23/IL-17A pathway, have been recently licensed or are in clinical development.
Nicolo Costantino Brembilla +3 more
doaj +1 more source
Cytokine and Lipid Mediator Regulation of Group 2 Innate Lymphoid Cells (ILC2s) in Human Allergic Airway Disease. [PDF]
, 2017 The recent discovery of group 2 innate lymphoid cells (ILC2s) has caused a paradigm shift in the understanding of allergic airway disease pathogenesis.
Cavagnero, Kellen, Doherty, Taylor A
core +2 more sources
Parasites & Vectors, 2017 Background Liver fibrosis is an excessive wound-healing reaction that requires the participation of inflammatory cells and hepatic stellate cells (HSCs).
Lina Zhou +10 more
doaj +1 more source
BATF acts as an essential regulator of IL-25–responsive migratory ILC2 cell fate and function
Science immunology, 2020 BATF-deficient mice lack iILC2 cells, which serve as an important early source of IL-4/IL-13 upon helminth infection. Early epithelial responder Innate lymphoid cell 2 (ILC2) cells can be defined as two distinct cell subsets based on responsiveness to IL-
Mindy M. Miller +5 more
semanticscholar +1 more source