The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Clinical Investigation of IL-31, TOS and GSH in the Sera of Gastric Cancer Females Patients In Iraq. [PDF]
Mahdi MA, Jumaa AH, Dawood YJ.
europepmc +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Il contributo analizza il rapporto tra i recenti cambiamenti demografici che l'Italia sta attraversando e la legge 194/1978 sull'interruzione volontaria di gravidanza, mettendo in luce l'incidenza dell'aborto sul calo demografico e soprattutto sull ...
Gambino, G, GAMBINO, GABRIELLA
core
IL-4, TSLP and IL-31 Cytokine Profiles as Related to Psychometric Measures in Patients with Mastocytosis. [PDF]
Romantowski J +5 more
europepmc +1 more source
IL-31 and IL-8 in Cutaneous T-Cell Lymphoma: Looking for Their Role in Itch. [PDF]
Abreu M +13 more
europepmc +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
La morte e il diritto: il problema dei trapianti d’organo (Profilo penalistico)
L’intervento è circoscritto ai casi di espianto d’organi dai defunti, con esclusione delle ipotesi di trapianti tra viventi. Dal punto di vista penalistico si esclude la tutelabilità del cadavere in quanto tale, che viene considerato solo come oggetto ...
ALESSANDRI, ALBERTO
core
WISIT vaccines based on IL-31-derived peptides as a novel therapeutic approach for chronic pruritic dermatoses. [PDF]
Schmidhuber S +5 more
europepmc +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source

