ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar +8 more
wiley +1 more source
Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis +9 more
wiley +1 more source
Possible Role of Interleukin-31/33 Axis in Imatinib Mesylate-Associated Skin Toxicity
Imatinib mesylate is a small-molecule tyrosine kinase inhibitor (TKi) designed to target c-ABL and BCR-ABL, approved for the treatment of chronic myeloid leukemia and gastrointestinal stromal tumors.
Caterina Musolino +7 more
doaj +1 more source
Summary: Background: Prurigo nodularis is a chronic skin disease characterised by intensely pruritic, hyperkeratotic nodules. Vixarelimab, a human monoclonal antibody, binds to the beta subunit of the oncostatin M receptor, inhibiting signalling of both
Howard Sofen +10 more
doaj +1 more source
Well-posed lateral boundary conditions for spectral semi-implicit semi-Lagrangian schemes : tests in a one-dimensional model [PDF]
The aim of this paper is to investigate the feasibility of well-posed lateral boundary conditions in a Fourier spectral semi-implicit semi-Lagrangian one-dimensional model.
Benard, Pierre +2 more
core +2 more sources
Politiche locali per i rom e i sinti, fra dinamiche di consenso e effettività eugenetica [PDF]
Il 6 giugno 2008, poco dopo le cinque di mattina, a Milano una cinquantina di agenti della polizia di stato, dei carabinieri e della polizia locale hanno eseguito un controllo e fotografato i documenti dei circa 35 cittadini italiani residenti al civico ...
Vitale, Tommaso
core +1 more source
Epidemiological changes of hepatocellular carcinoma at the beginning of the twenty-first century: from the emerging role of metabolic diseases as etiological factors to the need of a revision of the staging system [PDF]
Introduzione e scopo: la rapida diffusione delle malattie dismetaboliche sta modificando l’epidemiologia dell’epatocarcinoma (HCC). Scopo della tesi è, attraverso quattro studi, analizzare l’impatto di questi cambiamenti nella gestione clinica del ...
Pecorelli, Anna <1985>
core +1 more source
Increased levels of serum IL‐31 in chronic spontaneous urticaria* [PDF]
Please cite this paper as: Increased levels of serum IL‐31 in chronic spontaneous urticaria. Experimental Dermatology 2010; 19: 464–466. Abstract: IL‐31 represents a novel cytokine involved in pruritic skin diseases including atopic ...
Ulrike, Raap +6 more
openaire +2 more sources
Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus +6 more
wiley +1 more source
Escape from immunotherapy: possible mechanisms that influence tumor regression/progression [PDF]
Tumor escape is one major obstacle that has to be addressed prior to designing and delivering successful immunotherapy. There is compelling evidence to support the notion that immunogenic tumors, in murine models and cancer patients, can be rejected by ...
Ahmad, M, Ali, SA, Rees, RC
core +1 more source

