Results 231 to 240 of about 3,545,338 (242)
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Journal of Investigative Dermatology, 2022
Atopic dermatitis (AD) is an inflammatory skin disease characterized by skin barrier dysfunction. Although Th2 cytokines downregulate the expression of epidermal barrier proteins, the signaling mechanism underlying these effects remains unclear. IL-33, a
X. Dai +6 more
semanticscholar +1 more source
Atopic dermatitis (AD) is an inflammatory skin disease characterized by skin barrier dysfunction. Although Th2 cytokines downregulate the expression of epidermal barrier proteins, the signaling mechanism underlying these effects remains unclear. IL-33, a
X. Dai +6 more
semanticscholar +1 more source
Brain, behavior, and immunity, 2022
Hyper-inflammatory reaction plays a crucial role in the pathophysiology of depression and anxiety disorders. However, the mechanisms underlying inflammation-induced anxiety changes remain poorly understood. Here, we showed that in the lipopolysaccharide (
Xiao Zhuang +16 more
semanticscholar +1 more source
Hyper-inflammatory reaction plays a crucial role in the pathophysiology of depression and anxiety disorders. However, the mechanisms underlying inflammation-induced anxiety changes remain poorly understood. Here, we showed that in the lipopolysaccharide (
Xiao Zhuang +16 more
semanticscholar +1 more source
Development of an interleukin (IL)-33 sandwich ELISA kit specific for mature IL-33
Journal of Immunoassay and Immunochemistry, 2016Interleukin (IL)-33 is an inflammatory cytokine and belongs to the IL-1 family of cytokines. There are eleven members of the IL-1 family of cytokines and all have important roles in host defense against infections. Their levels are increased during infection and in various auto-inflammatory diseases.
Eunsom, Kim +10 more
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Anti-fungal effect of IL-33: Regulation of neutrophil activities by IL-33
2012 7th International Forum on Strategic Technology (IFOST), 2012IL-33 is known to play an important role in Th2 immunity. In this study, we investigated the effect of IL-33 pretreatment on anti-fungal response using an acute Candida albicans peritoneal infection model. IL-33 pre-treatment induced a rapid fungal clearance and markedly reduced the C. albicans infection-associated mortality.
Hong Rae Cho, Byungsuk Kwon
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Role of IL-33 in transplant biology
European Cytokine Network, 2019Since the pro-inflammatory cytokine IL-33 and its receptor (ST2) are closely involved in regulating both innate and adaptive immune responses, it is conceivable that they may play an important role in organ transplantation. IL-33 is broadly expressed by multiple cell types such as fibroblasts, epithelial cells, and endothelial cells.
Ying, Jin +3 more
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IL-33: A Sheep in Wolf’s Clothing?
Science's STKE, 2007Cytokines are soluble factors that regulate intercellular communication by binding to specific cell-surface receptors and activating cellular responses. A small subset of cytokines, however, has been recognized to act in an intracrine manner without being secreted.
Massimo, Gadina, Caroline A, Jefferies
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Modern Rheumatology, 2011
To investigate the role of interleukin (IL)-33 in rheumatoid arthritis (RA) patients, we measured the serum levels of IL-33 in RA patients before and after the administration of etanercept. Twenty-four patients with RA were treated with etanercept. Clinical and laboratory examinations, including serum levels of C-reactive protein (CRP) and hemoglobin ...
Yasunori, Kageyama +3 more
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To investigate the role of interleukin (IL)-33 in rheumatoid arthritis (RA) patients, we measured the serum levels of IL-33 in RA patients before and after the administration of etanercept. Twenty-four patients with RA were treated with etanercept. Clinical and laboratory examinations, including serum levels of C-reactive protein (CRP) and hemoglobin ...
Yasunori, Kageyama +3 more
openaire +2 more sources
IL-33 meets allergens at the gate
Nature Immunology, 2018IL-33 is a mediator of allergic inflammation and is localized in mucosal tissues to respond rapidly to environmental insults. These include allergens themselves, which can directly activate IL-33 through their intrinsic proteolytic activity.
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The IL-33/ST2 Axis Is Not Required for the Profibrotic Effect of IL-33 in the Lungs
American Journal of Respiratory Cell and Molecular BiologySergei P, Atamas +3 more
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