Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Predictive roles of serum IL-33/ST2 and BDNF in depressed patients with repetitive transcranial magnetic stimulation: a pilot study. [PDF]
Wu S, Zuo X, Liu L, Yang M, Li X, Li S.
europepmc +1 more source
IL-33-mediated mast cell and eosinophil function requires isoprenylation. [PDF]
Burchett JR +11 more
europepmc +1 more source
Circulating IL-33 as a sensitive alarmin in systemic lupus erythematosus: a biomarker for disease activity and skin-specific manifestations. [PDF]
Li L +7 more
europepmc +1 more source
Influenza A/PR8 virus infection in mice suppresses basal and Oncostatin M-induced IL-33 expression in vivo and in vitro. [PDF]
Somani-Davis L +6 more
europepmc +1 more source
M2 polarization of macrophage induced by IL-33 promotes mouse sciatic nerve regeneration. [PDF]
Xu D +11 more
europepmc +1 more source
IL-33-Driven Macrophage Reprogramming as a Potential Immunometabolic Strategy for Herpes Simplex Keratitis. [PDF]
He Y +8 more
europepmc +1 more source
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When discovered in the early 2000s, interleukin-33 (IL-33) was characterized as a potent driver of type 2 immunity and implicated in parasite clearance, as well as asthma, allergy, and lung fibrosis. Yet research in other models has since revealed that IL-33 is a highly pleiotropic molecule with diverse functions.
Johnny, Bou Saba, Hēth R, Turnquist
openaire +2 more sources
Thrombin cleaves IL‐33 and modulates IL‐33‐activated allergic lung inflammation
Allergy, 2022AbstractBackgroundOrganisms have orchestrated coagulation and immune systems. Although a link between inflammation and haemostasis has been reported in asthma, the interaction mechanism has not been completely elucidated. Here, we investigated the direct link between the mammalian immune and coagulation systems.MethodsMice were administered protease or
Yuying Huang +17 more
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IL-33 is alarmin the uterus for labor
Immunity, 2023Timely labor is critical for both infant and maternal health, yet the mechanisms underlying the initiation of childbirth remain unclear. In this issue of Immunity, Siewiera et al. demonstrate a vital role for innate type 2 immune responses in controlling uterus-intrinsic onset of labor in mice.1.
Elizabeth A, Kennedy, Kellie Ann, Jurado
openaire +2 more sources

