Results 261 to 270 of about 1,106,140 (286)

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

IL-33 as a biomarker for disease severity in COPD with lung cancer comorbidity. [PDF]

Am J Cancer Res
Ren H, Cui Y, Lv X.
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Simultaneous Investigation of sST2, IL-33, and Caspase-3 Serum Levels in Non-small Cell Lung Cancer. [PDF]

In Vivo
Akdeniz FT, Barut Z, Avşar O, Arinç S, Isbir T.   +4 more
europepmc   +1 more source

Autocrine activity of engineered IL-33 mRNA enhances adoptive T-cell therapy for peritoneal carcinomatosis and synergizes with IL-12 mRNA. [PDF]

Theranostics
Arrizabalaga L, Di Trani CA, Gomar C, Moreno-Luqui D, Ardaiz N, Belsue V, González-Gomariz J, Ruiz-Guillamon D, Risson A, Zheng Y, Huarte E, Matos I, Melero I, Berraondo P, Aranda F.   +14 more
europepmc   +1 more source

The IL-33/ST2 Axis Promotes Traumatic Heterotopic Ossification by Driving Macrophage and Mast Cell-Mediated Inflammation via Autophagy Defects. [PDF]

Int J Biol Sci
Chen Z, Xu Y, Qu C, Luo G, Cai Z, Liu H, Sun Z, Zhou C, Li J, Fan C.   +9 more
europepmc   +1 more source

Auranofin Ameliorates Gouty Inflammation by Suppressing NLRP3 Activation and Neutrophil Migration via the IL-33/ST2-CXCL1 Axis. [PDF]

Cells
Yoo H, Choi A, Kim M, Gye Y, Jo H, Kwok SK, Park Y, Lee JJ.   +7 more
europepmc   +1 more source

Differential Expression of IFI16, IL-33 and CD55 Link Potential Common Pathogenic Mechanisms for COVID-19 and Ulcerative Colitis. [PDF]

J Multidiscip Healthc
Zhang F, Di Q, Li Y, Ye J, Wang B, Ding Y.   +5 more
europepmc   +1 more source

Lactate attenuates hepatic ischemia-reperfusion injury by reducing intrahepatic inflammation and suppressing hepatocyte-neutrophil interaction via the IL-33/ST2 pathway. [PDF]

Cell Commun Signal
Fang P, Zhang Z, Zhu J, Xu H, Han X, Xu N, Wang X, Zhou L, Du X, Jin H, Zhang D, Sun G.   +11 more
europepmc   +1 more source