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Ex Vivo and In Vitro Proteomic Approach to Elucidate the Relevance of IL-4 and IL-10 in Intervertebral Disc Pathophysiology. [PDF]
Bermudez-Lekerika P +9 more
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IL-4 drives exhaustion of CD8<sup>+</sup> CART cells. [PDF]
Stewart CM +20 more
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Early-life IL-4 administration induces long-term changes in microglia in the cerebellum and prefrontal cortex. [PDF]
Ferreira PA +9 more
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Effect of linex treatment on IFN-γ and IL-4 in mice infected with Trichinella. [PDF]
Atta SA +4 more
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The IL-4, IL-13 and IL-31 pathways in atopic dermatitis
Expert Review of Clinical Immunology, 2021Introduction: Atopic dermatitis (AD) is the most common inflammatory skin disease. It has a complex pathophysiology, with a combination of immune dysregulation and intrinsic barrier defects driving cutaneous inflammation and allergic symptomatology.
Celina Dubin +2 more
semanticscholar +1 more source
Science's STKE, 2005
Interleukin-4 (IL-4) is a cytokine produced by T H 2 type helper T cells and by mast cells, basophils, and eosinophils. This cytokine can elicit many responses, some of which are associated with allergy and asthma. Studies with long-term cell lines and primary cells have revealed differences in the signaling between
Ann, Kelly-Welch +2 more
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Interleukin-4 (IL-4) is a cytokine produced by T H 2 type helper T cells and by mast cells, basophils, and eosinophils. This cytokine can elicit many responses, some of which are associated with allergy and asthma. Studies with long-term cell lines and primary cells have revealed differences in the signaling between
Ann, Kelly-Welch +2 more
openaire +2 more sources
CD28 Costimulation Accelerates IL-4 Receptor Sensitivity and IL-4-Mediated Th2 Differentiation
The Journal of Immunology, 1999Abstract The development of Th1 and Th2 cells is determined by the type of antigenic stimulation involved in the initial cell activation step. Evidence indicates that costimulatory signals, such as those delivered by CD28, play an important role in Th2 development, but little is known about how CD28 costimulation contributes to Th2 ...
M, Kubo +6 more
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