Results 51 to 60 of about 1,990,850 (192)
Respirology Case Reports, 2021 Dupilumab, a human monoclonal antibody against interleukin‐4 (IL‐4) and IL‐13, has been approved for treating severe asthma and eosinophilic chronic rhinosinusitis (ECRS).
Yoshiro Kai +6 more
doaj +1 more source
Biomedicines, 2023 Background: it has been suggested that chronic low-grade inflammation plays an important role in the pathogenesis of polycystic ovary syndrome (PCOS).
Elena Vasyukova +8 more
doaj +1 more source
Expression regulation of MAO isoforms in monocytic cells in response to Th2 cytokines [PDF]
, 2005 Background: Th2-cytokines, such as interleukins-4 and –13 (IL-4, IL-13), have been identified as alternative stimuli of monocytes/macrophages. We have recently profiled the gene-expression pattern of IL-4-teated human peripheral monocytes and found that ...
Billett, E +4 more
core
Pifu-xingbing zhenliaoxue zazhiObjective To investigate the expression levels of type 2 inflammatory cytokines, IL-4 and IL-13, in the serum and blister fluid of patients with bullous pemphigoid (BP).
Yao ZHOU +6 more
doaj +1 more source
IL‐4 induces proliferation in prostate cancer PC3 cells under nutrient‐depletion stress through the activation of the JNK‐pathway and survivin up‐regulation [PDF]
, 2012 Interleukin (IL)‐4 plays a critical role in the regulation of immune responses and has been detected at high levels in the tumor microenvironment of cancer patients where it correlates with the grade of malignancy.
Alva, Ajjai S. +10 more
core +1 more source
Manufacturing Dendritic Cells for Immunotherapy: Monocyte Enrichment [PDF]
, 2020 Dendritic cells play a key role in activation of the immune system as potent antigen-presenting cells. This pivotal position, along with the ability to generate dendritic cells from monocytes and ready uptake of antigen, makes them an intriguing vehicle ...
Cox, Cheryl, Hopewell, Emily L.
core +1 more source
Iranian Journal of Allergy, Asthma and Immunology, 2014 Human basophils play a key role in allergic diseases such as asthma and in a variety of immunological disorders. The generation of IL-4 and IL-13 can be induced from basophil by IgE-mediated and non-IgE-mediated mechanisms.
Nahid Eskandari +3 more
doaj
IL-4 Is a Key Requirement for IL-4- and IL-4/IL-13-Expressing CD4 Th2 Subsets in Lung and Skin
Frontiers in Immunology, 2018 Although IL-4 is long associated with CD4 Th2 immune responses, its role in Th2 subset development in non-lymphoid tissues is less clear. We sought to better define IL-4’s role in CD4 Th2 responses by using transgenic mice that express a dual IL-4 AmCyan/
Melanie Sarah Prout +3 more
doaj +1 more source
Tissue Cytokine Responses in Canine Visceral Leishmaniasis [PDF]
, 2001 To elucidate the local tissue cytokine response of dogs infected with Leishmania chagasi, cytokine mRNA levels were measured in bone marrow aspirates from 27 naturally infected dogs from Brazil and were compared with those from 5 uninfected control ...
Courtenay, O. +6 more
core +2 more sources
Iatreia, 1995 <p class="MsoNormal"><span style="font-size: 9pt; font-family: Arial">Interleukln 13 (IL-13) is a recently discovered cytokine produced by TH2 Iymphocytes. Its most important physiological activity relates with suppression of Inflammatory and
Leonardo Vargas
doaj