Results 31 to 40 of about 18,242,260 (289)

Cytokine Profiles and Antibody Response Associated to Choclo Orthohantavirus Infection

open access: yesFrontiers in Immunology, 2021
BackgroundNew World Hantaviruses (NWHs) are the etiological agent underlying hantavirus cardiopulmonary syndrome (HCPS), a severe respiratory disease with high mortality rates in humans.
Tybbysay P. Salinas   +16 more
doaj   +1 more source

Cytokine responses to Schistosoma haematobium in a Zimbabwean population: contrasting profiles for IFN-γ, IL-4, IL-5 and IL-10 with age [PDF]

open access: yes, 2007
Background The rate of development of parasite-specific immune responses can be studied by following their age profiles in exposed and infected hosts. This study determined the cytokine-age profiles of Zimbabweans resident in a Schistosoma haematobium ...
Mduluza Takafira   +17 more
core   +1 more source

Association of IL-4 with pachychoroid neovasculopathy

open access: yesScientific Reports, 2022
Abstract The purpose of this study was to identify inflammatory cytokines that are associated with pachychoroid neovasculopathy (PNV). Seventy-five eyes of 75 patients with PNV, 145 eyes of 145 patients with neovascular age-related macular degeneration without pachyvessels, and 150 eyes of 150 normal subjects were examined for the levels of ...
Takashi Baba   +10 more
openaire   +3 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

IL-4-mediated signaling controls macrophage phenotype.

open access: yes, 2019
Comparison between model simulations and literature experimental data on IL-4 induced (A) STAT6 phosphorylation [65], (B-C) IRF-4 upregulation (time-course and at 24 h) [66, 67], (D) AKT activation [68], (E) PPARγ expression at 18 h [69, 70], (F-G) Arg-1
Aleksander S. Popel (7878506)   +5 more
core   +1 more source

Interleukin 4 induces rapid mucin transport, increases mucus thickness and quality and decreases colitis and Citrobacter rodentium in contact with epithelial cells

open access: yesVirulence, 2019
Citrobacter rodentium infection is a murine model for pathogenic intestinal Escherichia coli infection. C. rodentium infection causes an initial decrease in mucus layer thickness, followed by an increase during clearance.
S. Sharba   +12 more
doaj   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan   +18 more
wiley   +1 more source

Targeting IL-4 for the Treatment of Atopic Dermatitis

open access: yesImmunoTargets and Therapy, 2020
Andrea Chiricozzi,1,2 Martina Maurelli,3 Ketty Peris,1,2 Giampiero Girolomoni3 1Dermatologia, Dipartimento Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A.
Chiricozzi A   +3 more
doaj  

Single-Chain Soluble Receptor Fusion Proteins as Versatile Cytokine Inhibitors

open access: yesFrontiers in Immunology, 2020
Cytokines are small secreted proteins that among many functions also play key roles in the orchestration of inflammation in host defense and disease.
Aurora Holgado   +15 more
doaj   +1 more source

Pathogenesis of Atopic Dermatitis: Current Paradigm [PDF]

open access: yesIranian Journal of Immunology, 2019
Atopic dermatitis (AD) is characterized by skin inflammation, barrier dysfunction and chronic pruritus. In this review, recent advances in the pathogenesis of AD are summarized.
Masutaka Furue   +5 more
doaj   +1 more source

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