Results 51 to 60 of about 18,242,260 (289)

PROGNOSIS FOR PREDISPOSAL TO DEVELOPMENT OF VIRAL HEPATITIS C BASED ON G-308A TNFА, T-330G IL-2, С-590Т IL-4, С-703Т IL-5, AND C-592A IL-10 GENE POLYMORPHISMS

Медицинская иммунология, 2014
. The main objective of this work was to identify allelic variants of cytokine genes at the polymorphic positions of G-308A TNFА, T-330G IL-2, С-590Т IL-4, С-703Т IL-5, and C-592A IL-10, and to assess their contribution to predisposition and resistance ...
V. V. Avdoshina, V. V. Dortman, V. I. Konenkov, E. V. Beloborodova, N. V. Ryasantseva, I. O. Naslednikova, V. V. Novitsky   +6 more
doaj   +1 more source

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source

IL-4/IL-13 independent goblet cell hyperplasia in experimental helminth infections-4

, 2011
Open bar) and IL-4/IL-13(gray bar) mice 7 days and 10 days PI in small intestine sections. B) Intestinal adult worm burden 7 and 10 days post infection. Data representative of two experiments are shown. Data are means of four mice per group ± SEM.
Lizette CE Fick (58853), Frank Brombacher (52142), Reece G Marillier (58850), William GC Horsnell (58855), Mosiuoa Leeto (58854), Elizabeth M Smith (58852), Chesney Michels (58851), Benjamin Dewals (40167)   +7 more
core   +1 more source

Association of the Expression of IL-4 and IL-13 Genes, IL-4 and IgE Serum Levels with Allergic Asthma

Iranian Journal of Allergy, Asthma and Immunology, 2007
Immune and inflammatory responses mediated by cytokines, play important roles in the pathophysiology of asthma. These responses are associated with overexpression of Th2 cytokines such as IL-4 and IL-13.
Jalil Tavakkol Afshari, Reza Farid Hosseini, Sara Hosseini Farahabadi, Farhad Heydarian, Mohammad Hossein Boskabady, Rasoul Khoshnavaz, Alireza Razavi, Ehsan Ghayoor Karimiani, Gholamreza Ghasemi   +8 more
doaj  

EFFECTS OF IL-4 UPON THE ACTIVITY OF STAT6 TRANSCRIPTION FACTOR IN PERIPHERAL BLOOD LYMPHOCYTES IN BRONCHIAL ASTHMA

Медицинская иммунология, 2014
. The aim of the study is to specify the levels of STAT6, and phospho-STAT6 under the influence of IL-4 in patients with bronchial asthma (BA). The samples from ten healthy controls and thirty-three BA patients with allergic and non-allergic clinical ...
V. N. Mineev, L. N. Sorokina, M. A. Nyoma   +2 more
doaj   +1 more source

The influence of sepsis as a complication after trauma on immune response to injury [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2011
Introduction. Mortality rate in trauma complicated with sepsis is exceeding 50%. Outcome is not determined only by infection or trauma, but also by the intensity of immuno-inflammatory response. Objective.
Šurbatović Maja, Mirković Darko, Radaković Sonja S., Jevtić Miodrag, Filipović Nikola S.   +4 more
doaj   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Ex Vivo Cytokine mRNA Levels Correlate with Changing Clinical Status of Ethiopian TB Patients and their Contacts Over Time [PDF]

, 2008
There is an increasing body of evidence which suggests that IL-4 plays a role in the pathogenesis of TB, but a general consensus on its role remains elusive.
Tilahun, Hiwot, VACSEL Study Group, Wassie, L, Lawrence Yamuah, T Mark Doherty, Abebe, Markos, Zumla, A, Doherty, T Mark, Demissie, Abebech, Yamuah, Lawrence, Graham Rook, Rook, G, Doherty, TM, Abebe, M, Beyene Petros, Yamuah, L, Wassie, Liya, Rook, Graham, Petros, B, Aseffa, Abraham, Abebech Demissie, Andersen, P, Peter Andersen, Petros, Beyene, Andersen, Peter, Demissie, A, Markos Abebe, Aseffa, A, Zumla, Alimuddin, Hiwot Tilahun, VACSEL Study Grp, Liya Wassie, Alimuddin Zumla, Tilahun, H, Abraham Aseffa   +34 more
core   +1 more source

IL-4 and IL-13 promote COL1A1 and αSMA co-expression and upregulate receptors inhibitors repress IL-4 and IL-13-mediated prostate myofibroblast phenoconversion.

, 2022
N1 prostate fibroblasts were treated with 20 ng/ml of IL-13 or IL- 4, or 4 ng/ml TGFβ1 (positive control) for 48 hr, then co-immunostained for COL1A1 (PE-cy5-conjugated Ab, red), αSMA (fluorescein-conjugated Ab, green), or counterstained with nuclear ...
Mehrnaz Gharaee-Kermani (118877), Quentin D’Arcy (13919516), Jill A. Macoska (118895), Alisa Zhilin-Roth (13919519)   +3 more
core   +1 more source

Pro-inflammatory and counter-regulatory modulators of interleukin-5–driven eosinophil programs: a framework for precision medicine in eosinophilic diseases

Frontiers in Immunology
Interleukin-5 (IL-5) is central to eosinophil differentiation, survival, and activation. Subsequent studies confirmed IL-5 receptor expression and mapped downstream signaling, showing that IL-5 promotes not only survival but also trafficking and effector
Hisashi Sasaki, Jun Miyata, Jun Miyata, Koichi Fukunaga, Koichi Fukunaga   +4 more
doaj   +1 more source