Results 101 to 110 of about 18,323,172 (295)

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source

IL-4 and IL-13 Receptor Signaling From 4PS to Insulin Receptor Substrate 2: There and Back Again, a Historical View

Frontiers in Immunology, 2018
In this historical perspective, written in honor of Dr. William E. Paul, we describe the initial discovery of one of the dominant substrates for tyrosine phosphorylation stimulated by IL-4.
Achsah D. Keegan, Achsah D. Keegan, Jose Zamorano, Aleksander Keselman, Nicola M. Heller   +4 more
doaj   +1 more source

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess, Gustaf Glavå, Simon Skau, Hans‐Georg Kuhn, Maria Bäck, Marianne Jarfelt   +5 more
wiley   +1 more source

“We Cannot Talk as a Family”: Complexities of Survivorship Communication Among Hispanic/Latino Young Adult Survivors of Childhood Cancer, Parents, and Clinicians

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Young adult childhood cancer survivors (YA‐CCS) have an increased risk of treatment‐related health complications throughout their lives. Lifelong survivorship care is recommended, yet many YA‐CCS experience disruptions in care during pediatric‐to‐adult transitions and do not receive recommended survivorship care.
Kevin Shanchen Pu, Nicole Fernández‐Viña, Briana C. Martin‐Villa, Daniela Ramirez, Rebecca M. Lewinsohn, Mary Smith, Heidi Boynton, Lidia Schapira, Stephanie M. Smith   +8 more
wiley   +1 more source

Interleukin-4 (IL-4) induces protein tyrosine phosphorylation of the IL-4 receptor and association of phosphatidylinositol 3-kinase to the IL-4 receptor in a mouse T cell line, HT2

Journal of Biological Chemistry, 1993
To study the signal transduction mechanism of interleukin-4 (IL-4), we have examined the effects of IL-4 on protein tyrosine phosphorylation in a mouse IL-2-dependent T cell line, HT2. Mouse IL-4 induces HT2 proliferation in a dose-dependent manner.
K, Izuhara, N, Harada
openaire   +2 more sources

Disordered IL-33/ST2 activation in decidualizing stromal cells prolongs uterine receptivity in women with recurrent pregnancy loss [PDF]

, 2012
Decidualization renders the endometrium transiently receptive to an implanting blastocyst although the underlying mechanisms remain incompletely understood.
Nicou, M, Zoe Webster, Emma S. Lucas (109222), Sean James, Keisuke Murakami, Mulac-Jericevic, B, Murakami Keisuke, Yazan Abdallah, Jaya Nautiyal (109208), Sandra Šućurović (109212), Salker Madhuri S., Abdallah, Y, Nautiyal, Jaya, Marilena Nicou, Jan J Brosens, Biserka Mulac-Jericevic (54989), Lucas Emma S., Jennifer H Steel, Mulac-Jericevic Biserka, Marilena Nicou (109216), Webster Zoe, Brosens, J J, James Sean, Croy, B. A. (B. Anne), Nautiyal Jaya, Lucas, E S, Siobhan Quenby, Yogesh Singh (109219), Yogesh Singh, Madhuri S. Salker (109206), Nicou, Marilena, Imperial College London, Quenby, Siobhan, Singh, Y, James, S, Nicou Marilena, Abdallah Yazan, Webster, Zoe, Croy, B A, Quenby Siobhan, Yazan Abdallah (109236), Brosens, Jan J., Christian Mark, Mark Christian (22637), Šućurović, Sandra, Madhuri S Salker, Croy B. Anne, Mark Christian, Steel Jennifer H., Singh Yogesh, Christian, M, Keisuke Murakami (109225), Warwick, Siobhan Quenby (109244), Biserka Mulac-Jericevic, Jan J. Brosens (109247), Lucas, Emma S., Queens University Canada, Singh, Yogesh, Dr., B. Anne Croy (109241), Rijeka, Šućurović Sandra, Jaya Nautiyal, Yi-Wah Chan, B Anne Croy, Murakami, K, Chan, Yi-Wah, James, Sean G., Brosens Jan J., Zoe Webster (109211), Sandra Sućurović, Murakami, Keisuke, Steel, Jennifer H., Nautiyal, J, Chan Yi-Wah, Quenby, S, Webster, Z, Salker, Madhuri S., Sean James (109232), Steel, J H, Sucurovic, S, Yi-Wah Chan (109228), Christian, Mark, Mulac-Jericevic, Biserka, Abdallah, Yazan, Chan, Y W, Emma S Lucas, Salker, M S, Jennifer H. Steel (109209)   +88 more
core   +2 more sources

Dupilumab as an adjuvant treatment for keloid-associated symptoms

JAAD Case Reports, 2021
Audrey Jia Shin Wong, BS, Eingun James Song, MD   +1 more
doaj   +1 more source

Interleukin-4 and its receptor alpha in paediatric uncomplicated malaria patients from a Ghanaian case-control study

BMC Research Notes
Objectives This study investigated gene polymorphisms in the interleukin-4 (IL-4) and its receptor alpha (IL-4Rα) gene regions in human hosts with uncomplicated malaria.
Patrick Diaba-Nuhoho
doaj   +1 more source

Identifying Patterns of Hospitalizations Among Childhood Cancer Survivors: A Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood cancer survivors (CCSs) experience more hospitalizations than the general population. We aimed to identify distinct hospitalization patterns among Queensland CCSs and the associated characteristics. Methods Cases (aged ≤14 years) diagnosed between 1995 and 2019 while residents of Queensland were identified through the ...
Hai Pham, Teyl Engstrom, Peter Baade, Natalie Bradford, Sarah Pont, Louise Marquart‐Wilson, Natasha Nassar, Jason D. Pole   +7 more
wiley   +1 more source

CpG oligonucleotide activates Toll-like receptor 9 and causes lung inflammation in vivo [PDF]

, 2007
Background Bacterial DNA containing motifs of unmethylated CpG dinucleotides (CpG-ODN) initiate an innate immune response mediated by the pattern recognition receptor Toll-like receptor 9 (TLR9).
Schwederski Markus, Koch, Alexander, Schwederski, Markus, Ehrentraut Heidi, Baumgarten, Georg, Ehrentraut, Heidi, Hoeft, Andreas, Velten, Markus, Knüfermann, Pascal, Zacharowski Kai, Hoeft Andreas, Mersmann Jan, Knuefermann Pascal, Meyer Rainer, Grohé Christian, Baumgarten Georg, Zacharowski, Kai, Koch Alexander, Meyer, Rainer, Grohé, Christian, Velten Markus, Mersmann, Jan   +21 more
core   +1 more source