Results 181 to 190 of about 17,201,482 (284)

Improved VO₂max following anti-IL-5 therapy in severe eosinophilic CRSwNP: exploratory associations with cardiac inflammatory biomarkers. [PDF]

Eur Clin Respir J
Tidemandsen J, Rossing K, Homøe AS, Hostrup M, Backer V.   +4 more
europepmc   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Tra il "facchino" e il "filosofo" : "il terzo istruito"

, 2016
BINANTI, Luigino, Istruito, Tra il “facchino” e. il “filosofo”: il “Terzo   +1 more
core  

Expression of IL-17 and IL-31 in Genital Lichen Sclerosus

reservedBackground Il Lichen sclerosus et atrophicus (LSA) è una malattia dermatologica immuno-mediata che colpisce la cute e le mucose, in particolar modo le aree genitali di femmine e maschi.
CHINELLATO, ALBERTO
core  

Proteomic Identification of Plasma Biomarkers of Response to IL-5 Inhibitor Biologics in Healthy Subjects. [PDF]

Clin Transl Sci
Chekka LMS, Samarth DP, Howard KE, Guo Y, Mohamed EG, Decker E, Wheeler W, Wommack J, Gogain J, Deering J, Schrieber SJ, Wang YM, Strauss DG, Florian J, Hyland PL.   +14 more
europepmc   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Anti-IL-5 and anti-IL-5 receptor therapy significantly improves quality of life and FEV1 values in patients with severe asthma. [PDF]

Allergy Asthma Clin Immunol
Alfaro AOV, Vargas HCG, Díaz JM, Pinto JA, Cambero DCG, Cuellar EH, Zapata JAP, Domínguez AEL, Zapata JP, Ponce-Campos SD.   +9 more
europepmc   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Monoclonal antibodies targeting IL-5/5R or IL-4/13 pathways in eosinophilic myocarditis: a single-centre experience and systematic literature review. [PDF]

Eur Heart J Cardiovasc Pharmacother
Giordani AS, Menghi C, Baritussio A, Scognamiglio F, Vicenzetto C, Davanzo F, Iorio L, Marcolongo R, De Gaspari M, Rizzo S, Basso C, Padoan R, Caforio ALP.   +12 more
europepmc   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source