Results 61 to 70 of about 1,825,564 (240)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Immunomodulatory effect of hepatitis B virus (HBV) antigens and MRSA antigens on immune response

Medical Journal of Babylon
Background: Methicillin-resistant Staphylococcus aureus is one of the most common human invaders and causes different types of illness worldwide.
Entidhar A. Hadi, Mohammad Abd-Kadhum Al-Saadi, Kaiser N. Madlum   +2 more
doaj   +1 more source

Depemokimab and the twice-yearly regimen: pharmacological implications and therapeutic positioning in severe eosinophilic respiratory diseases

Frontiers in Immunology
Type 2 inflammatory diseases (T2D), notably severe eosinophilic asthma (SEA) and chronic rhinosinusitis with nasal polyps (CRSwNP), represent a significant global health burden due to their high morbidity, frequent exacerbations and reliance on systemic ...
A. M. Marra, E. Bizzi, A. Gidaro, F. Bini, S. Rotunno, S. Modica, E. Greco, A. Mauro, R. Mascolo, E. Tombetti, M. Lazzeroni, F. Paciullo, G. Abatianni, C. Gagliardi, S. Damanti, P. Rovere Querini   +15 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Il funzionamento della personalità secondo il DSM-5: DPA e SCID-5-AMPD

Phenomena Journal, 2019
In 2013, with the latest edition of the Diagnostic and Statistical Manual of Mental Disorder, an alternative section was introduced that enriched the evaluation of a dimensional aspect and this, in addition to the unleashing of criticism, has also ...
1 Laura Rapanà, 2 Claudio Barbaranelli
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Pro-inflammatory and counter-regulatory modulators of interleukin-5–driven eosinophil programs: a framework for precision medicine in eosinophilic diseases

Frontiers in Immunology
Interleukin-5 (IL-5) is central to eosinophil differentiation, survival, and activation. Subsequent studies confirmed IL-5 receptor expression and mapped downstream signaling, showing that IL-5 promotes not only survival but also trafficking and effector
Hisashi Sasaki, Jun Miyata, Jun Miyata, Koichi Fukunaga, Koichi Fukunaga   +4 more
doaj   +1 more source

Combined IL-2 Immunocomplex and Anti-IL-5 mAb Treatment Expands Foxp3+ Treg Cells in the Absence of Eosinophilia and Ameliorates Experimental Colitis

Frontiers in Immunology, 2019
Interleukin (IL)-2 is expressed during T cell activation and induces the proliferation and differentiation of T cells. CD4+Foxp3+ regulatory T cells (Tregs) constitutively express the high affinity IL-2 receptor (CD25/IL-2Rα) and rapidly respond to IL-2 ...
Hirohito Abo, Kyle L. Flannigan, Duke Geem, Vu L. Ngo, Akihito Harusato, Timothy L. Denning   +5 more
doaj   +1 more source

Structure and Function of IL-5 Receptor

YAKUGAKU ZASSHI, 1995
Interleukin-5 (IL-5) regulates the production and function of B cells, eosinophils and basophils. In particular, IL-5 plays a critical role in the development of CD5-positive B (B-1) cells. The pleiotropic activity of IL-5 on target cells is directly dependent on the initial binding to IL-5 specific cell-surface receptor (IL-5R).
openaire   +3 more sources