Results 221 to 230 of about 141,877 (234)

Analysis of the tumor microenvironment using imaging mass cytometry data

The tumor microenvironment (TME) plays a pivotal role in tumor development, influencing interactions with immune cells, tumor progression, and responses to treatment. Understanding the heterogeneity of the TME is essential for uncovering the mechanisms underlying cell-to-cell interactions and their contribution to tumor dynamics. Recent advancements in
Zuzana, Loncova, Zlatko, Trajanoski, Dietmar, Rieder   +2 more
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Imaging Mass Cytometry to Decipher the Maturation of Tertiary Lymphoid Structures

In the realm of inflammation, including conditions like cancers, infections, and autoimmune diseases, the emergence of tertiary lymphoid structures (TLS) holds significant implications for prognosis and treatment response. Yet, traditional methodologies such as immunohistochemistry and immunofluorescence falter in capturing the nuanced complexities of ...
Le Rochais, Marion, Ghamry-Barrin, Sarah, Panouillot, Marylou, Hémon, Patrice, Garaud, Soizic   +4 more
openaire   +3 more sources

Computational Methods for the Integration and Analysis of Imaging Mass Cytometry and Mass Spectrometry Imaging

Advances in molecular biology are partially dependent on methodological innovation. Spatially resolved multi-omics, for example, promises to interrogate tissue architectures and mechanisms at unprecedented detail. However, these new experimental techniques introduce computational challenges in disentangling complex data into interpretable bits.
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Multiplexed In Situ Imaging Mass Cytometry Analysis of the Human Endocrine Pancreas and Immune System in Type 1 Diabetes

Cell Metabolism, 2019
Yue J Wang, Daniel Traum, Jonathan Schug   +2 more
exaly  

Imaging mass cytometry in preclinical studies of lung cancer

Over the past 50 years, lung cancer has been responsible for the greatest number of cancer-related deaths worldwide. Despite improvements in cancer management and a large research effort toward developing targeted therapies, the 5-year survival rate after a lung cancer diagnosis is still only 23% (Quaresma et al., 2015; Siegel et al., 2023).
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Mass Cytometry Imaging for the Study of Human Diseases—Applications and Data Analysis Strategies

Frontiers in Immunology, 2019
Heeva Baharlou, Nicolas P Canete, Anthony L Cunningham   +2 more
exaly  

Insights into highly multiplexed tissue images: A primer for Mass Cytometry Imaging data analysis

TrAC - Trends in Analytical Chemistry, 2022
exaly  

Simultaneous Multiplexed Imaging of mRNA and Proteins with Subcellular Resolution in Breast Cancer Tissue Samples by Mass Cytometry

Cell Systems, 2018
Daniel Schulz, Vito R T Zanotelli, Denis Schapiro   +2 more
exaly  

Use of Imaging Mass Cytometry in Studies of the Tissue Microenvironment

2022
Ida Herdlevær, Lucia Lisa Petrilli, Fatime Qosaj, Maria Vinci, Dario Bressan, Sonia Gavasso   +5 more
openaire   +1 more source

Tissue Immunostaining for Imaging Mass Cytometry

Journal of Visualized Experiments
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