Results 21 to 30 of about 4,157 (168)

Substrate selectivity of human histidine methyltransferase METTL9. [PDF]

Protein Sci
Abstract Methylation of histidine residues in zinc transporters by histidine methyltransferase METTL9 plays an important role in modulating their metal‐binding properties. Here, we report synthetic, enzymatic, and computational studies on human METTL9‐catalyzed Nπ‐methylation of His375 in zinc transporter SLC39A5‐derived peptides in which the histidine
Ahmad S, Moesgaard L, Tornøe CW, Emmel P, Slusarczyk K, Drozak J, Kongsted J, Mecinović J.   +7 more
europepmc   +2 more sources

Daily carnosine and anserine supplementation alters verbal episodic memory and resting state network connectivity in healthy elderly adults

Frontiers in Aging Neuroscience, 2015
Carnosine and anserine are strong antioxidants, previously demonstrated to reduce cognitive decline in animal studies. We aimed to investigate their cognitive and neurophysiological effects, using functional MRI, on humans.Thirty-one healthy participants
Jaroslav eRokicki, Jaroslav eRokicki, Lucia eLi, Jun eKaneko, Etsuko eImabayashi, Tatsuhiro eHisatsune, Hiroshi eMatsuda   +6 more
doaj   +1 more source

Carnosine induces intestinal cells to secrete exosomes that activate neuronal cells.

PLoS ONE, 2019
Recently, we showed that imidazole dipeptide such as carnosine contained abundantly in chicken breast meat improves brain function in a double-blind randomized controlled trial. However, the underlying molecular mechanisms remain unknown.
Yuka Sugihara, Shiori Onoue, Kosuke Tashiro, Mikako Sato, Takanori Hasegawa, Yoshinori Katakura   +5 more
doaj   +1 more source

How change in chirality prevents β-amyloid type interaction in a protonated cyclic dipeptide dimer

, 2022
International audienceThe protonated dimers of the diketopiperazine dipeptide cyclo (LPhe-LHis) and cyclo (LPhe-DHis) are studied by laser spectroscopy combined with mass spectrometry to shed light on the influence of stereochemistry on the clustering ...
Lepère, Valéria, Le Barbu-Debus, Katia, Pérez-Mellor, Ariel, Zehnacker, Anne   +3 more
core   +1 more source

Determination of Imidazole Dipeptides and Related Amino Acids in Natural Seafoods by Liquid Chromatography–Tandem Mass Spectrometry Using a Pre-Column Derivatization Reagent

Foods
Imidazole dipeptides (IDPs) and taurine (Tau) have several health benefits and are known to be contained in natural seafoods. However, their levels vary widely in different natural seafoods, making their simultaneous determination desirable.
Mayu Onozato, Minori Horinouchi, Yuki Yoshiba, Tatsuya Sakamoto, Hiroshi Sugasawa, Takeshi Fukushima   +5 more
doaj   +1 more source

The reactions of [Au(dien)Cl]²⁺ with L-histidine-containing dipeptides. Dependence of complex formation on the dipeptide structure

, 2013
Reactions between the monofunctional [Au(dien)Cl] 2+ complex with L-histidine-containing dipeptides, L-histidyl-glycine (L-His-Gly), and glycyl-L-histidine (Gly-L-His) were studied by H NMR spectroscopy.
Glišić, Biljana, Rajković, Snežana, Djuran, Miloš   +2 more
core   +1 more source

Structure and collision-induced dissociation of the protonated cyclo His-Phe dipeptide: mechanistic studies and stereochemical effects

, 2021
The role of stereochemical factors on the structure and the fragmentation paths of the protonated cyclic dipeptide cyclo histidine–phenylalanine is studied under ion traps conditions by combining tandem mass spectrometry, laser spectroscopy, quantum ...
Ivan Alata, Pérez-Mellor, Ariel, Le Barbu-Debus, Katia, Lepere, Valeria, Ariel Pérez-Mellor, Anne Zehnacker, Alata, Ivan, Katia Le Barbu-Debus, Riccardo Spezia, Valeria Lepere, Spezia, Riccardo, Zehnacker, Anne   +11 more
core   +1 more source

Streptavidins Coordinate Biotin Sequestration and Self‐Resistance Within a Biotin‐Pathway Antibiotic Network

Advanced Science, EarlyView.
A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa, Jingjun Mo, Xiaotong Diao, Feng Xie, Tingting Wang, Haowen Zhao, Dalei Wu, Rolf Müller, Chengzhang Fu   +8 more
wiley   +1 more source

Dynamic Control of Nucleic Acids Self‐Assembly and Expression Using Photoswitches

Chemistry – A European Journal, EarlyView.
We review here the recent progress made in the design of molecular photoswitches, and highlight their implementation for the dynamic control over nucleic acids self‐assembly and expression. ABSTRACT Synthetic nucleic acids have become readily available and now constitute versatile building blocks in materials science—where they can be used to engineer ...
Noemí Nogal, Hugo Laigle, Maxime Mansy, Sébastien Ulrich, Mathieu Surin   +4 more
wiley   +1 more source

Electrochemical studies of ternary complexes of copper (II) with dipeptide or histidine and an amino acid [PDF]

, 1993
424-427The reduction steps of ternary complexes of Cu(II) with dipeptide, glycylglycine (gg) and amino acids ɑ-alanine (ala); tyrosine (tyr); and histidine and the amino acids ɑ-alanine (ala), tyrosine (tyr), phenylalanine (phe) and tryptophan (trp) have
Bhattacharya, Pabitra K, Chakraborty, Debjani   +1 more
core