Results 151 to 160 of about 95,350 (343)

Photo-induced decarboxylative radical cascade cyclization of unactivated alkenes: access to CF- and CF₂-substituted ring-fused imidazoles. [PDF]

RSC Adv
Wang H, Lin S, Hong H, Hu Z, Huang Y, Zhang X, Lin SN, Yang BM.   +7 more
europepmc   +1 more source

IL4I1⁺ Macrophages and TDO2⁺ Myofibroblasts Drive AhR‐Mediated Immunosuppression and Ferroptosis Resistance in Solid Predominant Lung Adenocarcinoma

Advanced Science, EarlyView.
Solid predominant lung adenocarcinoma exhibits an immune‐excluded, ferroptosis‐resistant niche enriched with IL4I1⁺ TAMs and TDO2⁺ myCAFs. Spatial and multi‐omics analyses reveal AhR‐driven crosstalk that promotes T cell exhaustion and therapy resistance. Blocking AhR with CH‐223191 restores ferroptosis sensitivity, and its combination with ferroptosis
Zhaoxuan Wang, Weijiao Xu, Lei Zhao, Lin Zhong, Wendan Yu, Shengmin Wang, Lu Sun, Tao Guo, Fengzhou Li, Zhuoshi Li, Lei Fang, Shiqing Wang, Guohui Zhang, Guoqing Xue, Wei Guo, Shilei Zhao, Chundong Gu   +16 more
wiley   +1 more source

Electrochemical cyclization of alkynes to construct five-membered nitrogen-heterocyclic rings. [PDF]

Beilstein J Org Chem
Peng L, Wang T, Yuan Z, Li B, Tang Z, Liu X, Li H, Jiang G, Zeng C, Wong HNC, Peng XS.   +10 more
europepmc   +1 more source

Imidazol-Lipide

, 2011
Zur chemischen Implementierung eines neuen Konzepts zu synthetischer Zellen - im Rahmen des EU-Projekts PACE - wurden zell-typische Reaktionssysteme (membranformendes-(1), metabolisches-(2) und genetisches-(3) Subsystem) umgesetzt und analysiert.
openaire   +1 more source

SODIUM BISULFITE AS AN EFFICIENT AND ECONOMICAL CATALYST FOR ONE-POT SYNTHESIS OF 2, 4, 5 TRISUBTITUTED IMIDAZOLES FROM BENZIL, AMMONIUM ACETATE AND AROMATIC ALDEHYDES BY MICROWAVE IRRADIATION

, 2018
Arvind Tapase Arvind Tapase, ijrbat
openalex   +1 more source

HSP70 Interactome‐Mediated Proteolysis Targeting Chimera (HSP70‐PROTAC) for Ferroptosis‐Driven Cancer Treatment

Advanced Science, EarlyView.
This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong, Yulong Li, Hui Liang, Zumei Wu, Shiqun Wang, Yichao Wang, Jieyu Xu, Yanning Lan, Maohua Cai, Guangzhao Pan, Haiyan Yang, Kai Miao, Zhe‐Sheng Chen, Fangfang Tao, Xuelei Ma, Jiang‐Jiang Qin   +15 more
wiley   +1 more source

Synthesis of 1-Fluoroalkyl-5-Substituted-1,2,3-Triazoles from Carbonyl-Stabilized Phosphonium Ylides. [PDF]

J Org Chem
Tichý D, Černý T, Filgas J, Voltrová S, Klepetářová B, Beier P.   +5 more
europepmc   +1 more source

ZIF‐67‐Confined Pd Single‐Atom Catalysts Implanted Into Polydopamine‐Modified Bamboo Microchannels for Robust Continuous‐Flow Hydrogenation

Advanced Science, EarlyView.
The report presents a facile room‐temperature method to stabilize Pd single‐atom catalysts within ZIF‐67 crystals during their formation. Despite an ultralow Pd loading (0.0014 wt%), the catalytic microreactor, featuring atomically dispersed Pd‐N4 sites in ZIF‐67, demonstrates superior robustness and maximized Pd utilization, significantly ...
Sisi Yao, Jiawei Han, Wenjun Zhang, Dengkang Guo, Shenjie Han, Yun Lu, Jingpeng Li   +6 more
wiley   +1 more source

Green synthesis of imidazole derivatives in a ternary deep eutectic solvent system. [PDF]

Sci Rep
Mohammad F, Azizi N, Mirjafari Z, Mokhtari J.   +3 more
europepmc   +1 more source

Pressure-induced amorphous zeolitic imidazole frameworks with reduced toxicity and increased tumor accumulation improves therapeutic efficacy In vivo

, 2020
Zhenqi Jiang, Yanying Li, Zhenni Wei, Bo Yuan, Yinjie Wang, Ozioma Udochukwu Akakuru, Yong Li, Juan Li, Aiguo Wu   +8 more
openalex   +1 more source