Results 201 to 210 of about 22,275 (301)

Formal Markovnikov Hydroazolation of Alkenes via Reductive Activation of Alkylthianthrenium Salts. [PDF]

J Am Chem Soc
Matthews AD, Lorenz JR, Wickens ZK.
europepmc   +1 more source

Accelerating Biosensor Discovery: A Computationally‐Driven Pipeline for Microplastics Monitoring

Advanced Intelligent Discovery, EarlyView.
A computationally guided pipeline unites molecular simulation, synthetic biology, electrochemical engineering, and machine learning to accelerate biosensor discovery. A Bacillus anthracis carbohydrate‐binding module is used to develop a high‐performance micro‐ and nanoplastics sensor with greatly reduced error and variability.
Gabriel X. Pereira, Marcos de C. Leite, Pedro H. M. Zanineli, Juliana N. Y. Costa, Débora M. Cunha, Sophia P. Serra, Pedro H. Sophia, Flávio M. Shimizu, Yasmin W. Moura, Célio C. Oliveira, Gabriel R. Schleder, Gabriela F. Persinoti, Leandro Merces, Renato S. Lima   +13 more
wiley   +1 more source

1‐Azabicyclo[1.1.0]butanes (ABBs) on the Map: Mechanistic Pathways for Catalytic Ring Opening and Functionalizations

Angewandte Chemie, EarlyView.
Catalytic strain‐release ring opening and functionalizations of 1‐azabicyclo[1.1.0]butanes (ABBs) represent a promising strategy for accessing diverse azetidine products. These transformations proceed via polar pathways, radical pathways, and hybrid mechanisms that combine both.
James Shao‐Jiun Yang, Hsuan‐Hung Liao   +1 more
wiley   +2 more sources

The Phosphatidylinositol 3-Kinase (PI3K) Inhibitor Inavolisib Has Breast-cancer Synergy Combined With Recombinant Methioninase But Not on Normal Cells. [PDF]

In Vivo
Kim J, Han Q, Li S, Miyashi Y, Ishiguro T, Bouvet M, Hoffman RM.   +6 more
europepmc   +1 more source

Recurrent Neurodevelopmental Disorder Associated With a Dominant‐Negative TOP2B H63Y Variant

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT We describe a 7 year‐old boy with severe neurodevelopmental disorder, medically‐refractory epileptic encephalopathy, hyperkinetic movement disorder, hypotonia, cerebral and cerebellar atrophy and hypomyelination who was found to have a heterozygous de novo TOP2B NM_001330700.2:c.187C>T, p.(His63Tyr) variant.
Zong Yi Ha, Leticia Dinatto, Kirsten Meagher, Colleen Guimond, Jan M. Friedman, Peter C. Stirling, Millan S. Patel   +6 more
wiley   +1 more source

SESMic: A Reagent for the Synthesis of 5-Membered Heteroaryl Masked Sulfinates. [PDF]

Org Lett
Chi Y, Chan GH, Moschitto MJ.
europepmc   +1 more source

Privileged nitrogen heterocycles in anticancer drug discovery: recent advances on imidazole, indole, and pyrimidine scaffolds. [PDF]

RSC Adv
Govindarajan M, Maji L, Mannathan S, Kumaradoss KM, Chowdhury A, Jois SD, Baskar B.   +6 more
europepmc   +1 more source

Cobalt‐Catalyzed C─N Bond Formation via Metal‐Hydride Hydrogen Atom Transfer (MHAT)

Angewandte Chemie, EarlyView.
Cobalt‐catalyzed metal‐hydride hydrogen atom transfer (Co‐MHAT) converts simple alkenes into C─N bonds under mild, near‐neutral conditions. A shared Co─H‐initiated radical/organocobalt intermediate is channeled into radical trapping, radical‐polar crossover, or radical ligand transfer, unifying hydroamination, hydroazidation, hydroamidation, and remote
Arman Khosravi, Ming‐Yu Ngai
wiley   +2 more sources

Nahinfrarot‐Photoschalten durch direkte Anregung—die nächste Herausforderung

Angewandte Chemie, EarlyView.
Molekulare Photoschalter können endlich direkt mit Licht aus dem Nahinfrarotbereich angeregt werden. Dieser Kurzaufsatz fasst den derzeitigen Entwicklungsstand, die Designprinzipien für niedrigenergetische Lichtresponsivität und die dadurch möglichen außergewöhnlichen Anwendungen zusammen.
Diptiprava Sahoo, Elias Ciekalski, Henry Dube   +2 more
wiley   +1 more source