Results 221 to 230 of about 22,275 (301)

Erweiterung der Peptidligation auf Saure pH‐Bereiche und Schnittstellen mit Glykosylierten und Phosphorylierten Aminosäuren

Angewandte Chemie, EarlyView.
Ein pyridinhaltiges Ligationsauxiliar beseitigt einen wesentlichen Engpass der Peptidligationschemie. Der für die Ligation nutzbare pH‐Bereich von 2,0–7,5 hilft, Epimerisierung zu vermeiden. Die native chemische Ligation (NCL) verläuft an praktisch jeder Ligationsstelle, einschließlich Reaktionen an β‐verzweigten sowie O‑glykosylierten oder O ...
Sebastian Trunschke, Antonia Feida, Hendrik Hanebrink, Arseniy Galashov, Alina Herfort, Oliver Seitz   +5 more
wiley   +1 more source

Oxidative Potential of Atmospheric Particulate Matter: A Review of the Role of Metal-Organic Interactions, Mechanistic Insights, and Key Determinants. [PDF]

Environ Sci Technol
Lin M, Yu JZ.
europepmc   +1 more source

Synthesis of Large‐ and Medium‐Sized Heterobiaryl Atropisomeric Rings and Atropopeptides by Catalytic Intramolecular SNAr

Angewandte Chemie, EarlyView.
Catalytic, intramolecular N‐heterocycle arylation by nucleophilic aromatic substitution (SNAr) is now available for synthesis of highly strained macrocycles and medium‐sized heterobiaryl atropisomeric rings, including atropopeptides. Key to the approach is the ability to generate a strong base catalytically, taking advantage of base‐embedding ...
Alireza Abbasi Kejani, Paritosh Dey, Nicholas H. Stillman, Daniel M. Andrade, Michal Šimek, Martin Dračínský, Daniel Bím, Paulo H. S. Paioti   +7 more
wiley   +1 more source

Green synthesis of imidazole derivatives in a ternary deep eutectic solvent system. [PDF]

Sci Rep
Mohammad F, Azizi N, Mirjafari Z, Mokhtari J.   +3 more
europepmc   +1 more source

Exploring the potential of vamotinib in Ph+ leukemias: is it indeed a 3rd generation tyrosine kinase-inhibitor? [PDF]

J Hematol Oncol
Lucini C, Sponseiler I, Bandian AM, Senkiv J, Lion T.   +4 more
europepmc   +1 more source

Exacerbation of myasthenia gravis after zoledronic acid and denosumab: a novel clinical observation with therapeutic implications. [PDF]

BMC Neurol
Canneva S, De Giovanni A, Pagella F, Trompetto C, Grandis M, Mori L.   +5 more
europepmc   +1 more source

Near Infrared Photoswitching by Direct Excitation—A Next Frontier

Angewandte Chemie International Edition, EarlyView.
Molecular photoswitches finally enter the spectral realm of near‐infrared for their direct excitation. This minireview summarizes the current state‐of‐the‐art, the design principles for achieving such low‐energy light responsiveness, and the unique applications that are unlocked by it.
Diptiprava Sahoo, Elias Ciekalski, Henry Dube   +2 more
wiley   +1 more source

A Brønsted-based deep eutectic solvent as a green catalyst for the sustainable one-pot synthesis of 1,2,4,5-tetrasubstituted imidazole derivatives: <i>in vitro</i> cytotoxicity and <i>in silico</i> binding studies on HepG2 cells. [PDF]

RSC Adv
Ngoc Tran TA, Nguyen LD, Nguyen KN, Dang PH, Nguyen HT.   +4 more
europepmc   +1 more source

Aza‐Büchner–Curtius–Schlotterbeck Reaction Enables Selective Construction of Quaternary Carbon Centers

Angewandte Chemie International Edition, EarlyView.
We introduce the Aza‐Büchner–Curtius–Schlotterbeck (ABCS) reaction: A mild, catalyst‐free method for homologating aryl imines. Diverging from the traditional BCS mechanism, the diazo intermediate undergoes selective C─C insertion to form an all‐carbon quaternary center.
Simon O. Angerer, Vincent George, Aryaman Pattanik, Gaia Carpentiero, Tereza Morcinková, Julia Rehbein, Burkhard König   +6 more
wiley   +1 more source

Therapeutic drug monitoring guides personalized ponatinib dose reduction for chronic myeloid leukemia. [PDF]

Int J Hematol
Abumiya M, Takahashi N.
europepmc   +1 more source