Results 241 to 250 of about 30,850 (304)
Synthetic Strategies to Access Fluorinated Azoles. [PDF]
European J Org ChemEl-Gaber MKA +4 more
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Therapeutic Tools for Vulvovaginal Candidiasis: Current and Emerging Antifungal Agents. [PDF]
J Fungi (Basel)Quindós G +6 more
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Journal of Medicinal Chemistry, 1975
A series of analogs of N-benzylimidazole was prepared and tested for hypolipidemic activity. Both plasma cholesterol and triglyceride-lowering activity were found in several members of the series. The most active compounds were N-3-methoxy-, N-4-methoxy-, and N-4-methylbenzylimidazole. Structure-activity relationships are discussed.
K H, Baggaley +5 more
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A series of analogs of N-benzylimidazole was prepared and tested for hypolipidemic activity. Both plasma cholesterol and triglyceride-lowering activity were found in several members of the series. The most active compounds were N-3-methoxy-, N-4-methoxy-, and N-4-methylbenzylimidazole. Structure-activity relationships are discussed.
K H, Baggaley +5 more
openaire +2 more sources
American Pharmacy, 1991
Vaginal candidiasis is a common infection in women for which several effective therapeutic agents are currently available. Clotrimazole and miconazole were introduced in 1975, and both recently became available over the counter. These imidazole agents have largely replaced nystatin as primary therapy because of greater antifungal activity and shorter ...
C R, Lee, C A, McKenzie, A, Nobles
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Vaginal candidiasis is a common infection in women for which several effective therapeutic agents are currently available. Clotrimazole and miconazole were introduced in 1975, and both recently became available over the counter. These imidazole agents have largely replaced nystatin as primary therapy because of greater antifungal activity and shorter ...
C R, Lee, C A, McKenzie, A, Nobles
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THE UTILIZATION OF IMIDAZOLES BY YEASTS
Canadian Journal of Microbiology, 1967Eleven imidazoles were tested singly as nitrogen sources for 62 strains of yeast. L-Histidine and histamine were used by most strains, D-histidine by some, and histidinol only by a few. Four yeasts grew on compounds containing nitrogen only in the imidazole ring.
LaRue, T. A., Spencer, J. F. T.
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Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1984
Abstract Myoglobin is photooxidized when exposed to visible light in the presence of a sensitizer. In 8 M urea medium this photooxidation is followed by photodynamic interpeptide crosslinking. A partial inhibition of crosslinking is caused by lysine, mercaptoethanol and hydroxylamine, and by amidination of NH2 groups in the protein molecule. Complete
J. Van Steveninck +2 more
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Abstract Myoglobin is photooxidized when exposed to visible light in the presence of a sensitizer. In 8 M urea medium this photooxidation is followed by photodynamic interpeptide crosslinking. A partial inhibition of crosslinking is caused by lysine, mercaptoethanol and hydroxylamine, and by amidination of NH2 groups in the protein molecule. Complete
J. Van Steveninck +2 more
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Computational study of imidazole and methyl imidazoles
Journal of Molecular Structure: THEOCHEM, 1994Abstract A semiempirical and ab initio study of the structures of imidazole, methyl imidazoles and the corresponding protonated and deprotonated ions is presented. The energies of the different isomers and tautomers are discussed and the protonation and deprotonation energies are given.
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The Significance of the Imidazole Ring in Anticonvulsant Activity of (Arylalkyl)imidazoles
Archiv der Pharmazie, 1988AbstractThe imidazole ring in nafimidone [1‐(2‐naphthyl)‐2‐(1‐imidazolyl)ethanone] was substituted with various groups to investigate the significance of the imidazole ring in anticonvulsant activity. For this purpose, some 2‐acetylnaphthalene derivatives and their reduction products were synthesized. Several N‐alkylation methods were used to prepare 2‐
U, Caliş +3 more
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Stimulation of glycolysis by imidazole
Life Sciences, 1973Abstract Imidazole stimulated glycolysis by rat diaphragm homogenates; this effect increased as the concentration of imidazole was raised. The simultaneous changes in concentration of some of the glycolytic intermediates suggested an action of imidazole at a step between triose phosphate and pyruvate.
R, Parvin, N, Kalant
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