Results 241 to 250 of about 30,622 (304)

One-Pot Telescoping S-Transfer and Trifluoromethylation for the Synthesis of 2-CF₃S-Imidazoles with N-Oxides as Convenient Precursors. [PDF]

J Org Chem
Poper WK, Ma JA, Jasiński M.
europepmc   +1 more source

Anodic Desulfurization of Heterocyclic Thiones - A Synthesis to Imidazoles and Analogues. [PDF]

Org Lett
Cesca D, Arnold P, Kaldre D, Falivene F, Sladojevich F, Puentener K, Waldvogel SR.   +6 more
europepmc   +1 more source

A simple patch test (empty tablet cover patch test) demonstrating ornidazone as offending agent in a patient of fixed drug eruption: Report of a clinical case, a new modified technique and systematic review of literature.

Indian J Pharmacol
Balamurugan R, Sarma P, Nagendran P, Nicodemus DS, Sharma S.   +4 more
europepmc   +1 more source

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Hypolipidemic imidazoles

Journal of Medicinal Chemistry, 1975
A series of analogs of N-benzylimidazole was prepared and tested for hypolipidemic activity. Both plasma cholesterol and triglyceride-lowering activity were found in several members of the series. The most active compounds were N-3-methoxy-, N-4-methoxy-, and N-4-methylbenzylimidazole. Structure-activity relationships are discussed.
K H, Baggaley, M, Heald, R M, Hindley, B, Morgan, J L, Tee, J, Green   +5 more
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Imidazoles forVaginitis

American Pharmacy, 1991
Vaginal candidiasis is a common infection in women for which several effective therapeutic agents are currently available. Clotrimazole and miconazole were introduced in 1975, and both recently became available over the counter. These imidazole agents have largely replaced nystatin as primary therapy because of greater antifungal activity and shorter ...
C R, Lee, C A, McKenzie, A, Nobles
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Imidazole: Fungitoxic Derivatives

Science, 1967
Study of several new types of fungitoxic derivatives of imidazole reveals that imidazoles substituted on the imine nitrogen atom are likely to be active if the substituent is electron-attracting, and if the atom connecting it to the imidazolyl moiety has tetrahedral geometry.
H, Tolkmith, J N, Seiber, P B, Budde, D R, Mussell   +3 more
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Synthesis of difluoromethylthio imidazole from methylthio imidazole

Journal of Fluorine Chemistry, 1996
Abstract Demethylation of methylthio imidazole 1 via a Pummerer rearrangement onto the corresponding sulfoxide 2 afforded imidazole thiol 4 which was then difluoromethylated with the sodium chlorodifluoroacetate/NaI system in 71% overall yield.
Pierre Deprez, Jean-Paul Vevert
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Imidazole–imidazole stacking in some inorganic complexes

Inorganica Chimica Acta, 2009
Abstract Reaction of CuCl2 · 2H2O with the 1:1 condensate (L) of 2-(2-aminoethyl)pyridine and 1-methyl-2-imidazolecarboxaldehyde in methanol yields monomeric CuLCl2.H2O (1). Recrystallisation of 1 from aqueous methanol medium containing excess of PF 6 − affords the 1D coordination polymer [CuLCl]n(PF6)n (2).
Senjuti De, Michael G.B. Drew, Núria Aliaga-Alcalde, Dipankar Datta   +3 more
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Imidazole anticonvulsants: structure-activity relationships of [(biphenylyloxy)alkyl]imidazoles

Journal of Medicinal Chemistry, 1987
The [(biphenylyloxy)alkyl]imidazoles were found to be potent anticonvulsants. The most potent compound of the series, 1-[2- ([1,1'-biphenyl]-2-yloxy)ethyl]-1H-imidazole (4), had an ED50 of 15.5 mg/kg against maximal-electroshock-induced seizures in mice after oral administration; the horizontal screen ED50 was 320 mg/kg, revealing that the compound has
D W, Robertson, E E, Beedle, R, Lawson, J D, Leander   +3 more
openaire   +2 more sources