Results 31 to 40 of about 524 (174)
The palladium-catalyzed coupling of imines, chloroformates, organotin reagents, and carbon monoxide leads to the one-pot formation of ketocarbamates in good yields.
Bruce A. Arndtsen (1310721) +2 more
core +1 more source
ABSTRACT Aims Chronic kidney disease (CKD) is a major complication of type 2 diabetes mellitus (T2DM), driven in part by oxidative stress and the accumulation of advanced glycation end products (AGEs). Oleanolic acid (OA), a natural triterpene present in olive‐derived matrices, may modulate AGE metabolism.
Aída García‐González +14 more
wiley +1 more source
Recent Advances in Bioconjugation of Aromatic Amino Acid Residues by a Reactivity‐Guided Approach
This review highlights recent advances in the bioconjugation of aromatic amino acids residues, focusing on strategies that leverage their inherent chemical reactivity to enable precise and versatile modifications of biomacromolecules, illustrating relevant applications.
Bruno M. da S. Santos +3 more
wiley +1 more source
1,3-Dipolar cycloaddition reactions of nitrile imines are a powerful tool for the construction of spirocyclic frameworks, yet controlling chemoselectivity remains challenging when dipolarophiles contain multiple reactive sites.
Maria E. Filkina +4 more
doaj +1 more source
Intracellular Catalytic Photooxygenation of α‐Synuclein Amyloid
Amyloid‐selective catalytic photooxygenation reduces amyloid toxicity, aggregation tendencies, and seeding activities. Achieving therapeutic catalysis for intracellular amyloids is challenging due to conflicting oxygenation and reductive cellular environments.
Atsushi Iwai +11 more
wiley +1 more source
Up until now, arylidene-4-imidazolones and dialkyl-(4,4’)-imidazolones derivatives are subject of longing for scientists both in the field of materials with fluorescence properties, and medical area, in particular for the treatment of diseases such as ...
Frippiat, Steven
core +1 more source
Bioinspired Light‐Driven Organic Rotary Molecular Systems
This review explores the evolution of bioinspired light‐driven rotary molecular systems (RMSs), highlighting the integration of natural chromophore‐based fragments to enhance quantum efficiency, photostability, and biocompatibility. Key strategies to optimize photochemical performance and broaden functional applications are discussed, providing a ...
Lidia Hortigüela, Sara P. Morcillo
wiley +1 more source
Background and Purpose Methanobactins are peptides with high copper affinity and potential to treat Wilson disease. We examined how two methanobactins (ARBM101 and MB‐OB3b) affected copper handling in the LPP Atp7b−/− Wilson disease rat model, compared to penicillamine or saline, by 64Cu positron emission tomography/magnetic resonance imaging ...
Emilie Munk Lynderup +11 more
wiley +1 more source
A preorganized tetrapodal building block, incorporating α‐carboline units, self‐assembles to form a 3D hydrogen‐bonded organic framework (HOF). The expanded hydrogen bonding between the heteroaromatic substructures, along with intermolecular π–π interactions, spontaneously build up an interpenetrated architecture that bestows an extraordinary ...
Manuel Carrera +10 more
wiley +2 more sources
This multicenter study demonstrated that fingertip autofluorescence, measured non‐invasively, correlates with clinical risk factors and vascular complications in patients with type 2 diabetes. Our findings suggest that fingertip autofluorescence may serve as a convenient marker for evaluating both microvascular and macrovascular complications in ...
Minoru Takeshita +16 more
wiley +1 more source

