Results 51 to 60 of about 524 (174)

Simple and Efficient Copper-Catalyzed Approach to 2,4-Disubstituted Imidazolones

, 2016
Some imidazolone derivatives are biological and pharmaceutical active molecules and the chromophores of the fluorescent proteins. In this communication, a simple and efficient approach to 4-arylidene-2-alkyl-4,5-dihydro-1H-imidazol-5-ones (2,4 ...
Haijun Yang (166821), Hua Fu (178428), Xiaoyu Gong (2284477), Hongxia Liu (1544371), Yufen Zhao (144572), Yuyang Jiang (158422)   +5 more
core   +1 more source

Engineered Living Energy Materials

Interdisciplinary Materials, Volume 4, Issue 3, Page 412-455, May 2025.
Engineered living energy materials (ELEMs) are nascent research frontier for enabling sustainable energy conversion and storage. These materials exhibit unique characteristics such as self‐regeneration, biodegradability, environmental response, and evolutionary adaptability. This paper overviews different energy conversion bio‐modules, summarizes their
Xinyi Yuan, Haiyi Xu, Xingwu Liu, Jicong Zhang, Jing Li, Qianyi Liang, Bolin An, Giuseppe Maria Paternò, Minyue Zhang, Yuqing Tang, Chen Zhang, Dake Xu, Chao Zhong, Ke Li, Xinyu Wang   +14 more
wiley   +1 more source

Insights from the fructose‐derived product glucoselysine: Revisiting the polyol pathway in diabetic complications

Journal of Diabetes Investigation, Volume 16, Issue 4, Page 569-577, April 2025.
This review focuses on the enhanced polyol pathway and the formation of glucoselysine and discusses its biochemical characteristics and clinical significance. ABSTRACT Advanced glycation end‐products (AGEs) have been extensively studied because of their close association with the onset and progression of diabetic complications.
Hiroko Yamaguchi, Ryoji Nagai
wiley   +1 more source

In silico evaluation of cis-dihydroxy-indeno[1,2-d]imidazolones as inhibitors of glycogen synthase kinase-3: synthesis, molecular docking, physicochemical data, ADMET,MD simulation, and DFT calculations

Journal of Saudi Chemical Society
A new series of cis-dihydroxy-indeno[1,2-d]imidazolone compounds with distinct structures were synthesized to investigate their potential as inhibitors of the Glycogen synthase kinase 3 (GSK-3).
Nahid Mahmoodi, Mohammad Bayat, Davood Gheidari, Zahra Sadeghian   +3 more
doaj   +1 more source

SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 1-(4-CHLOROPHENYL)-2-(3-SULPHOXYPHENYL-4-(4-SUBSTITUTED BENZYLIDENE)-5-IMIDAZOLONES

, 2017
Imidazolones are believed to be associated with several pharmacological activities. Their significance lies in the fact that they show diverse biological activities.
R. M. Kedar, S. A. Deshmukh
core   +1 more source

Identification and study of new NF‐κB‐inducing kinase ligands derived from the imidazolone scaffold

Archiv der Pharmazie, Volume 358, Issue 1, January 2025.
A new family of NF‐κB‐inducing kinase (NIK) ligands bearing an imidazolone moiety were synthesized. The best compound showed a dose‐dependent inhibition of p100 to p50 processing in cellular assays, a key step in nuclear factor κB (NF‐κB) activation. Based on computational techniques, a plausible binding mode is proposed.
Francisco Maqueda‐Zelaya, Lara Valiño‐Rivas, Ana Milián, Sara Gutiérrez, José Luis Aceña, Javier Garcia‐Marin, Mª Dolores Sánchez‐Niño, Juan J. Vaquero, Alberto Ortiz   +8 more
wiley   +1 more source

Rhodium Carbenoid N−H Insertion Reactions of Primary Ureas:  Solution and Solid-Phase Synthesis of Imidazolones

, 2016
The solution and solid-phase synthesis of imidazolones is reported. The key step for the preparation of these compounds is the N−H insertion reaction of primary ureas into highly reactive rhodium carbenoid intermediates.
Guido Koch (2700208), Jürg Zimmermann (2700205), Sang-Hyeup Lee (2648521), Kim D. Janda (163029), Bruce Clapham (2631298)   +4 more
core   +1 more source

Synthesis and direct, catalytic functionalization of the C-H bond of imidazolones : novel access towards GFP-like fluorophores

, 2017
Les imidazolones sont des molécules étudiées de longue date, soit en tant que molécules bioactives, soit pour leurs propriétés de fluorescence, l'exemple le plus connu étant la GFP.
Muselli, Mickaël
core  

Syntheses and functionalizations of imidazolones cores : innovatives uses of isocyanides and oxazolines

, 2020
A ce jour, les dérivés d’imidazolones-4-arylidènes et dialkyles-(4,4’)-imidazolones font l’objet de nombreuses convoitises pour les scientifiques tant sur le domaine des matériaux via ses propriétés de fluorescence, que sur celui du médical, en ...
Frippiat, Steven
core  

Charting the Chemical Reaction Space around a Multicomponent Combination: Controlled Access to a Diverse Set of Biologically Relevant Scaffolds. [PDF]

Angew Chem Weinheim Bergstr Ger, 2023
Nadal Rodríguez P, Ghashghaei O, Schoepf AM, Benson S, Vendrell M, Lavilla R.   +5 more
europepmc   +2 more sources