Results 31 to 40 of about 1,650,706 (352)

Construction and validation of an immune infiltration-related risk model for predicting prognosis and immunotherapy response in low grade glioma

BMC Cancer, 2023
Background Low grade glioma (LGG) is considered a heterogeneous tumor with highly variable survival and limited efficacy of immunotherapy. To identify high-risk subsets and apply immunotherapy effectively in LGG, the status and function of immune ...
Jinna Li, Qing Guo, Rui Xing
doaj   +1 more source

New insights from integrated bioinformatics analysis: the role of circadian rhythm disruption and immune infiltration in obstructive sleep apnea disease

Frontiers in Immunology, 2023
BackgroundCircadian rhythm disruption and immune infiltration are both closely associated with the development of Obstructive sleep apnea (OSA) disease and a variety of cardiovascular and neurological complications, but their interactions with OSA ...
Xinyue Zhang, Yixuan Wang, Zhou Pan, Ke Hu   +3 more
doaj   +1 more source

Activated lymphocyte recruitment into the tumor microenvironment following preoperative sipuleucel-T for localized prostate cancer. [PDF]

, 2014
BackgroundSipuleucel-T is a US Food and Drug Administration-approved immunotherapy for asymptomatic or minimally symptomatic metastatic castration-resistant prostate cancer (mCRPC). Its mechanism of action is not fully understood.
Amling, Christopher L, Carroll, Peter, Chan, Stephen, Corman, John, Fong, Lawrence, Frohlich, Mark W, Lewis, Jera, Sheikh, Nadeem A, Simko, Jeffrey, Sims, Robert B, Small, Eric J, Stephenson, Robert A, Weinberg, Vivian   +12 more
core   +2 more sources

Sp1 induced gene TIMP1 is related to immune cell infiltration in glioblastoma

Scientific Reports, 2022
Tumor immune microenvironment exerts a profound effect on the population of infiltrating immune cells. Tissue inhibitor of matrix metalloproteinase 1 (TIMP1) is frequently overexpressed in a variety of cells, particularly during inflammation and tissue ...
Lu Liu, Shuyao Yang, Ke-chen Lin, Xiao-Ran Yu, Jiaqi Meng, Chaolong Ma, Zheng Wu, Yuchao Hao, Ning Chen, Qi Ge, Wenli Gao, Xiang Wang, E. Lam, Lin Zhang, Fangcheng Li, Bilian Jin, D. Jin   +16 more
semanticscholar   +1 more source

The Prognostic Value of GNG7 in Colorectal Cancer and Its Relationship With Immune Infiltration

Frontiers in Genetics, 2022
Background: G Protein Subunit Gamma 7 (GNG7) is an important gene that regulates cell proliferation and induces apoptosis. However, the correlation between GNG7 expression and immune infiltration as well as patient prognosis of colorectal cancer (CRC ...
Can Fang, Rulei Zhong, Chenyang Qiu, Bing-bing Zou   +3 more
doaj   +1 more source

The Heterogeneity of Immune Cell Infiltration Landscape and Its Immunotherapeutic Implications in Hepatocellular Carcinoma

Frontiers in Immunology, 2022
Immunotherapy, closely associated with immune infiltration and tumor mutation burden (TMB), is emerging as a promising strategy for treating tumors, but its low response rate in hepatocellular carcinoma (HCC) remains a major challenge. Herein, we applied
Yuanyuan Guo, Jing Yang, Kaidi Ren, Xueke Tian, Hua Gao, Xin Tian, Xiaojian Zhang, Q. Kan   +7 more
semanticscholar   +1 more source

SERPINE1 associated with remodeling of the tumor microenvironment in colon cancer progression: a novel therapeutic target

BMC Cancer, 2021
Background The change of immune cell infiltration essentially influences the process of colorectal cancer development. The infiltration of immune cells can be regulated by a variety of genes.
Shaokun Wang, Li Pang, Zuolong Liu, Xiangwei Meng   +3 more
doaj   +1 more source

Perivascular adipose tissue inflammation in vascular disease [PDF]

, 2017
Perivascular adipose tissue (PVAT) plays a critical role in the pathogenesis of cardiovascular disease. In vascular pathologies, perivascular adipose tissue increases in volume and becomes dysfunctional, with altered cellular composition and molecular ...
Guzik, Tomasz J., Nosalski, Ryszard
core   +1 more source

N6-Methyladenosine Modification Participates in the Progression of Hepatitis B Virus-Related Liver Fibrosis by Regulating Immune Cell Infiltration

Frontiers in Medicine, 2022
Aim N6-methyladenosine (m6A) modification has been demonstrated to play an important part in hepatitis B virus (HBV) infection and immune response. This study aims to further investigate whether m6A modification plays an important role in the progression
Tong Zhao, Jianni Qi, T. Liu, Hao Wu, Qiang Zhu   +4 more
semanticscholar   +1 more source

A Transendothelial Leukocyte Transmigration Model Based on Computational Fluid Dynamics and BP Neural Network

Frontiers in Bioengineering and Biotechnology, 2022
The mechanism of immune infiltration involving immune cells is closely related to various diseases. A key issue in immune infiltration is the transendothelial transmigration of leukocytes.
Qingjia Chi, Zichang Yang, Hua-Ping Liang   +2 more
doaj   +1 more source