Results 61 to 70 of about 1,650,706 (352)

BIRC5 is a prognostic biomarker associated with tumor immune cell infiltration

Scientific Reports, 2021
BIRC5 is an immune-related gene that inhibits apoptosis and promotes cell proliferation. It is highly expressed in most tumors and leads to poor prognosis in cancer patients.
Linlong Xu, Wen-Hui Yu, Han Xiao, Kang Lin   +3 more
semanticscholar   +1 more source

Prognostic characteristics of immune subtypes associated with acute myeloid leukemia and their identification in cell subsets based on single-cell sequencing analysis

Frontiers in Cell and Developmental Biology, 2022
Immune genes play an important role in the development and progression of acute myeloid leukemia (AML). However, the role of immune genes in the prognosis and microenvironment of AML remains unclear.
Jie Lu, Guowei Zheng, Ani Dong, Xinyu Chang, Xiting Cao, Mengying Liu, Xuezhong Shi, Chunmei Wang, Yongli Yang, Xiaocan Jia   +9 more
doaj   +1 more source

Experimental rat models of chronic allograft nephropathy: a review [PDF]

, 2014
Chronic allograft nephropathy (CAN) is the leading cause of late allograft loss after renal transplantation (RT), which continues to remain an unresolved problem. A rat model of CAN was first described in 1969 by White et al. Although the rat model of RT
Haylor, John, Shrestha, Badri
core   +2 more sources

cGAS-STING pathway expression correlates with genomic instability and immune cell infiltration in breast cancer

npj Breast Cancer
Genomic instability, as caused by oncogene-induced replication stress, can lead to the activation of inflammatory signaling, involving the cGAS-STING and JAK-STAT pathways.
Mengting Chen, Shibo Yu, T. van der Sluis, M. Zwager, C. Schröder, B. van der Vegt, M. V. van Vugt   +6 more
semanticscholar   +1 more source

INHBA is a Prognostic Biomarker and Correlated With Immune Cell Infiltration in Cervical Cancer

Frontiers in Genetics, 2022
Background: Inhibin A (INHBA), a member of the TGF-β superfamily, has been shown to be differentially expressed in various cancer types and is associated with prognosis. However, its role in cervical cancer remains unclear.
Kaidi Zhao, Y. Yi, Zhou-Sheng Ma, Wei Zhang   +3 more
semanticscholar   +1 more source

Modulation of the host Th1 immune response in pigeon protozoal encephalitis caused by Sarcocystis calchasi [PDF]

, 2013
Pigeon protozoal encephalitis (PPE) is an emerging central-nervous disease of domestic pigeons (Columba livia f. domestica) reported in Germany and the United States.
Gruber, Achim D., Kaspers, Bernd, Klopfleisch, Robert, Lierz, Michael, Meyer, Anne, Olias, Philipp   +5 more
core   +3 more sources

NAT10-mediated upregulation of GAS5 facilitates immune cell infiltration in non-small cell lung cancer via the MYBBP1A-p53/IRF1/type I interferon signaling axis

Cell Death Discovery
Interactions of tumor cells with immune cells in the tumor microenvironment play an important role during malignancy progression. We previously identified that GAS5 inhibited tumor development by suppressing proliferation of tumor cells in non-small cell
Zimu Wang, Jing Luo, Hairong Huang, Li Wang, Tangfeng Lv, Zhao-feng Wang, Chuling Li, Yimin Wang, Jiaxin Liu, Qinpei Cheng, Xueying Zuo, Liwen Hu, Mingxiang Ye, Hongbing Liu, Yong Song   +14 more
semanticscholar   +1 more source

The immunopeptidome landscape associated with T cell infiltration, inflammation and immune editing in lung cancer

Nature Cancer, 2023
One key barrier to improving efficacy of personalized cancer immunotherapies that are dependent on the tumor antigenic landscape remains patient stratification.
Anne I. Kraemer, Chloé Chong, Florian Huber, HuiSong Pak, Brian J. Stevenson, Markus Müller, Justine Michaux, Emma Ricart Altimiras, S. Rusakiewicz, L. Simó-Riudalbas, E. Planet, M. Wiznerowicz, J. Dagher, D. Trono, G. Coukos, S. Tissot, M. Bassani-Sternberg   +16 more
semanticscholar   +1 more source

Characterizing the Tumor Microenvironment and Its Prognostic Impact in Breast Cancer

Cells
The tumor microenvironment (TME) is crucial in cancer development and therapeutic response. Immunotherapy is increasingly recognized as a critical component of cancer treatment.
Wenjuan Zhang, Alex Lee, Amit K. Tiwari, Mary Qu Yang   +3 more
doaj   +1 more source

JAM3 is a potential risk biomarker for predicting prognosis and immune cell infiltration by regulating epithelial-mesenchymal transition in bladder cancer.

Biomolecules & biomedicine
To identify novel biomarkers for predicting prognosis and immune function in bladder cancer (BC) patients, we combined weighted correlation network analysis (WGCNA) and least absolute shrinkage and selection operator (LASSO) regression analysis by using ...

semanticscholar   +1 more source