Results 201 to 210 of about 2,266,569 (385)

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

open access: yesAdvanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun   +7 more
wiley   +1 more source

Immune checkpoint TIM-3 in tumor immunotherapy. [PDF]

open access: yesActa Biochim Biophys Sin (Shanghai)
Ma S, Zhu M, Ma C, Li C.
europepmc   +1 more source

Soluble immune checkpoint factors reflect exhaustion of antitumor immunity and response to PD-1 blockade

open access: gold
Hidetoshi Hayashi   +28 more
openalex   +1 more source

The pattern of tumor progression on first-line immune checkpoint inhibitor-based systemic therapy for Chinese advanced hepatocellular carcinoma –CLEAP 004 study [PDF]

open access: gold
Chao-Xu Yang   +13 more
openalex   +1 more source

FAPα+ Macrophages Orchestrate Immune Evasion in Multiple Myeloma by Dual Regulation of PD‐L1 and T Cell Senescence

open access: yesAdvanced Science, EarlyView.
Fibroblast activation protein alpha‐positive (FAPα+) macrophages, a distinct subset of multiple myeloma (MM)‐associated macrophages, drive immune evasion in MM through multi‐faceted mechanisms. FAPα physically interacts with vimentin (VIM) and triggers its phosphorylation at the S72 residue, which in turn induces PD‐L1 transcription. Additionally, FAPα
Huiyao Gu   +15 more
wiley   +1 more source

The role of immune checkpoint molecules in cancers. [PDF]

open access: yesFront Immunol
Zhang M   +7 more
europepmc   +1 more source

Data from A Dual PI3K/HDAC Inhibitor Induces Immunogenic Ferroptosis to Potentiate Cancer Immune Checkpoint Therapy

open access: gold, 2023
Fushun Fan   +11 more
openalex   +1 more source

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