Results 11 to 20 of about 121,779 (302)
Immune Evasion Strategies of Schistosomes [PDF]
Human schistosomes combat the unique immune systems of two vastly different hosts during their indirect life cycles. In gastropod molluscs, they face a potent innate immune response composed of variable immune recognition molecules and highly phagocytic ...
Jacob R. Hambrook, Patrick C. Hanington
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Filoviral Immune Evasion Mechanisms [PDF]
The Filoviridae family of viruses, which includes the genera Ebolavirus (EBOV) and Marburgvirus (MARV), causes severe and often times lethal hemorrhagic fever in humans. Filoviral infections are associated with ineffective innate antiviral responses as a
Christopher F. Basler+5 more
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Innate immune evasion by alphaviruses
Alphaviruses contain many human and animal pathogens, such as CHIKV, SINV, and VEEV. Accumulating evidence indicates that innate immunity plays an important role in response to alphaviruses infection.
Yihan Liu+7 more
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Immune Evasion Strategies of Glioblastoma [PDF]
Glioblastoma (GBM) is the most devastating brain tumor, with associated poor prognosis. Despite advances in surgery and chemoradiation, the survival of afflicted patients has not improved significantly in the past three decades.
Seyed-Mostafa eRazavi+5 more
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Viral mechanisms of immune evasion [PDF]
During the millions of years they have coexisted with their hosts, viruses have learned how to manipulate host immune control mechanisms. Viral gene functions provide an overview of many relevant principles in cell biology and immunology. Our knowledge of viral gene functions must be integrated into virus-host interaction networks to understand viral ...
Antonio Alcamı́, Ulrich H. Koszinowski
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Immune Evasion of Mycoplasma bovis [PDF]
Mycoplasma bovis (M. bovis) causes various chronic inflammatory diseases, including mastitis and bronchopneumonia, in dairy and feed cattle. It has been found to suppress the host immune response during infection, leading to the development of chronic ...
Hussam Askar+6 more
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Pathogen evasion of social immunity
AbstractTreating sick group members is a hallmark of collective disease defence in vertebrates and invertebrates alike. Despite substantial effects on pathogen fitness and epidemiology, it is still largely unknown how pathogens react to the selection pressure imposed by care intervention.
Miriam Stock+8 more
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Overcoming Immune Evasion in Melanoma [PDF]
Melanoma is the most aggressive and dangerous form of skin cancer that develops from transformed melanocytes. It is crucial to identify melanoma at its early stages, in situ, as it is “curable” at this stage. However, after metastasis, it is difficult to treat and the five-year survival is only 25%.
Kevinn Eddy, Suzie Chen
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Spirochetal Lipoproteins and Immune Evasion [PDF]
Spirochetes are a major threat to public health. However, the exact pathogenesis of spirochetal diseases remains unclear. Spirochetes express lipoproteins that often determine the cross talk between the host and spirochetes. Lipoproteins are pro-inflammatory, modulatory of immune responses, and enable the spirochetes to evade the immune system. In this
Christodoulides, Alexei+2 more
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Evasion of immune responses by Trypanosoma cruzi, the etiological agent of Chagas disease
Infection with the protozoan parasite Trypanosoma cruzi leads to Chagas disease, which affects millions of people in Latin America. Infection with T. cruzi cannot be eliminated by the immune system.
G.A. DosReis
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