Results 11 to 20 of about 241,317 (354)

Filoviral Immune Evasion Mechanisms [PDF]

Viruses, 2011
The Filoviridae family of viruses, which includes the genera Ebolavirus (EBOV) and Marburgvirus (MARV), causes severe and often times lethal hemorrhagic fever in humans. Filoviral infections are associated with ineffective innate antiviral responses as a
Christopher F. Basler, Gaya K. Amarasinghe, Craig S. Brown, Reed S. Shabman, Parameshwaran Ramanan, Daisy W. Leung   +5 more
doaj   +3 more sources

Immune Evasion Strategies of Schistosomes [PDF]

Frontiers in Immunology, 2021
Human schistosomes combat the unique immune systems of two vastly different hosts during their indirect life cycles. In gastropod molluscs, they face a potent innate immune response composed of variable immune recognition molecules and highly phagocytic ...
Jacob R. Hambrook, Patrick C. Hanington
doaj   +3 more sources

Innate immune evasion by alphaviruses

Frontiers in Immunology, 2022
Alphaviruses contain many human and animal pathogens, such as CHIKV, SINV, and VEEV. Accumulating evidence indicates that innate immunity plays an important role in response to alphaviruses infection.
Yihan Liu, Yihan Liu, Yihan Liu, Yupei Yuan, Yupei Yuan, Leiliang Zhang, Leiliang Zhang, Leiliang Zhang   +7 more
doaj   +3 more sources

Immune Evasion Strategies of Glioblastoma [PDF]

Frontiers in Surgery, 2016
Glioblastoma (GBM) is the most devastating brain tumor, with associated poor prognosis. Despite advances in surgery and chemoradiation, the survival of afflicted patients has not improved significantly in the past three decades.
Seyed-Mostafa eRazavi, Karen E Lee, Benjamin E Jin, Parvir S Aujla, Sharareh eGholamin, Gordon eLi   +5 more
doaj   +3 more sources

Loss of histone macroH2A1 in hepatocellular carcinoma cells promotes paracrine-mediated chemoresistance and CD4+CD25+FoxP3+ regulatory T cells activation [PDF]

, 2020
Rationale: Loss of histone macroH2A1 induces appearance of cancer stem cells (CSCs)-like cells in hepatocellular carcinoma (HCC). How CSCs interact with the tumor microenvironment and the adaptive immune system is unclear. Methods: We screened aggressive
Drovakova A., Giallongo S., Li Volti G., Lo Re O., Mazza T., Rappa F., Roskams T., Sanna P., Tsochatzis E., Van Haele M., Vinciguerra M., Vinh Luong T.   +11 more
core   +1 more source

Predictive Virtual Infection Modeling of Fungal Immune Evasion in Human Whole Blood

Frontiers in Immunology, 2018
Bloodstream infections by the human-pathogenic fungi Candida albicans and Candida glabrata increasingly occur in hospitalized patients and are associated with high mortality rates.
Maria T. E. Prauße, Maria T. E. Prauße, Teresa Lehnert, Teresa Lehnert, Sandra Timme, Sandra Timme, Kerstin Hünniger, Kerstin Hünniger, Ines Leonhardt, Ines Leonhardt, Oliver Kurzai, Oliver Kurzai, Oliver Kurzai, Marc Thilo Figge, Marc Thilo Figge, Marc Thilo Figge   +15 more
doaj   +1 more source

Spirochetal Lipoproteins and Immune Evasion. [PDF]

, 2017
Spirochetes are a major threat to public health. However, the exact pathogenesis of spirochetal diseases remains unclear. Spirochetes express lipoproteins that often determine the cross talk between the host and spirochetes.
Boyadjian, Ani, Christodoulides, Alexei, Kelesidis, Theodoros   +2 more
core   +1 more source

Immune Evasion Mechanism and AXL

Frontiers in Oncology, 2021
Extensive interest in cancer immunotherapy is reported according to the clinical importance of CTLA-4 and (PD-1/PD-L1) [programmed death (PD) and programmed death-ligand (PD-L1)] in immune checkpoint therapies. AXL is a receptor tyrosine kinase expressed
Hye-Youn Son, Hwan-Kyu Jeong
doaj   +1 more source

Immune evasion of the CD1d/NKT cell axis [PDF]

, 2018
Many reviews on the CD1d/NKT cell axis focus on the ability of CD1d-restricted NKT cells to serve as effector cells in a variety of disorders, be they infectious diseases, cancer or autoimmunity.
Brutkiewicz, Randy R., Liu, Jianyun, Yunes-Medina, Laura   +2 more
core   +1 more source

Immune Evasion of G-CSF and GM-CSF in Lung Cancer [PDF]

Tuberculosis and Respiratory Diseases
Tumor immune evasion is a complex process that involves various mechanisms, such as antigen recognition restriction, immune system suppression, and T cell exhaustion.
Yeonhee Park, Chaeuk Chung
doaj   +1 more source